1986
DOI: 10.1111/j.1748-1716.1986.tb07849.x
|View full text |Cite
|
Sign up to set email alerts
|

Pilocarpine‐stimulated salivary flow rate and salivary glucose concentration in alloxan diabetic rats. Influence of severity and duration of diabetes

Abstract: Pilocarpine-stimulated salivary flow rate and glucose concentration were estimated in short-term (1 month) and long-term (12 months) alloxan diabetic rats and in age-matched nondiabetic controls. Diabetic rats had significantly decreased salivary flow rate which was negatively correlated to blood glucose concentration. They also had increased salivary glucose levels, which were positively correlated to blood glucose values, when the blood glucose values were above 15 mmol l-1, suggesting a threshold mechanism … Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1
1

Citation Types

7
40
3
8

Year Published

1991
1991
2020
2020

Publication Types

Select...
9
1

Relationship

0
10

Authors

Journals

citations
Cited by 47 publications
(60 citation statements)
references
References 11 publications
7
40
3
8
Order By: Relevance
“…In contrast, Belazi et (10) did not find any difference between normal and diabetic children regarding calcium concentrations in saliva. There are reports indicating that diabetic patients have more acidic saliva (8,11,13), whereas others have not reported this difference (10,12). It is still not clear whether caries risk can be higher in diabetic pediatric patients due to affected salivary factors as compared to controls (9,14).…”
Section: Introductionmentioning
confidence: 97%
“…In contrast, Belazi et (10) did not find any difference between normal and diabetic children regarding calcium concentrations in saliva. There are reports indicating that diabetic patients have more acidic saliva (8,11,13), whereas others have not reported this difference (10,12). It is still not clear whether caries risk can be higher in diabetic pediatric patients due to affected salivary factors as compared to controls (9,14).…”
Section: Introductionmentioning
confidence: 97%
“…The salivary glucose concentration was observed lower during the period of better metabolic control in patients with diabetes mellitus in an earlier study [9].…”
Section: Discussionmentioning
confidence: 62%
“…Lower salivary flow rates in diabetic than non-diabetic patients has been reported (Ben-Aryeh et al 1988, Thorstensson et al 1989a), but there are contradictory results by Belazi et al (1998). Poor control of diabetes relates to a decreased flow of saliva (Harrison & Bowen 1987, while the association between the blood glucose and salivary glucose levels is quite inconsistent (Sharon et al 1985, Reuterving et al 1987, Ben-Aryeh et al 1988, Darwazeh et al 1991. A high glucose level in the oral cavity is proposed as a reason for dental caries, but the results concerning the salivary glucose level are not consistent (Sharon et al 1985, Ben-Aryeh et al 1988, Thorstensson et al 1989b, Darwazeh et al 1991, Belazi et al 1998.…”
Section: Dental Cariesmentioning
confidence: 99%