Phytol – A biosurfactant from the aquatic weed Hydrilla verticillata

Prabha, Shashi; Karthik, C.; Chandrika, S. Hema

doi:10.1016/j.bcab.2019.01.026

Cited by 17 publications

(6 citation statements)

References 31 publications

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“…The bioactive molecule n -Hexadecanoic acid has reported to have multiple biological properties in Vitex negundo (Kumar et al 2019 ; Enerijiofi et al 2021 ). The phytol, a bioactive compound reported earlier in several species like Hydrilla verticillate, Gracilaria edulis and Carissa carandas with diversified medicinal uses (Prabha et al 2019 ; Rao et al 2019 ). The compound 9,12,15-Octadecatrienoic acid was known to possess several biological properties like analgesic, anesthetic, anticonvulsant, anti-inflammatory, antioxidant, anti-pyretic, antibacterial (Kalaivani et al 2012 ); anticancer, antihistaminic, hepatoprotective, hypocholesterolemic, nematicide (Rao et al 2019 ) in Andrographis paniculata and Carissa carandas and also known to reduce complications in Covid-19 patients (Weill et al 2020 ).…”

Section: Discussionmentioning

confidence: 99%

GC–MS profiling and antibacterial activity of Solanum khasianum leaf and root extracts

2022

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Background Solanum khasianum is an important medicinal herb of the Solanaceae family. The present study was focused to determine the bioactive compounds in S. khasianum leaf and root extract by GC–MS analysis and their antibacterial activity by agar well diffusion method. Results Sixteen bioactive compounds were detected in leaf extract and thirty-two compounds in root methanolic extract by GC–MS. The major potent compounds identified in leaf and root extracts were heptadecane 9-hexyl (43.65%) and stigmasterol (23.18%). The root extract showed increased antibacterial activity than leaf extract. Conclusion These extracts possessed significant antibacterial activity against the tested bacterial isolates in dose-dependent manner. This study provides the phytoconstituents, antibacterial property and scientific evidence for the traditional claim and use of S. khasianum.

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Section: Discussionmentioning

confidence: 99%

GC–MS profiling and antibacterial activity of Solanum khasianum leaf and root extracts

2022

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“…pyogenes is attributed to the presence of α-pinene and linalool in the EOs [ 15 ]. Strong antibacterial activity is reported for phytol [ 69 ]. The antibacterial and anti-biofilm effects of α-humulene extracted from plants have been proven [ 70 ].…”

Section: Resultsmentioning

confidence: 99%

A GC-MC analysis of chemical compounds and identification of the antibacterial characteristics of the essential oil of two species exclusive to Iranian habitats: New chemotypes

Ghavam

2022

PLoS ONE

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Background The diversity found in the chemical compounds of a single species in different regions results in different biologic characteristics which can be considered as a strong source for identifying new chemotypes. Hymenocrater incanus Bunge and Dracocephalum kotschyi Boiss. are exclusive species of the Lamiaceae family which grow in the western and central habitats of Iran. This study was designed and carried out to determine the yield, identify the chemical compounds, and evaluate the antimicrobial characteristics of the essential oil (EO) of these two species in Iran for the first time. Methods The flowering twigs of the species D. kotschyi and H. incanus were collected from the villages of Totmach and Kamu in Isfahan province respectively, in May 2019. The EO of these plants was extracted and separated using the water distillation method, utilizing the Clevenger device. The EO compounds were analyzed using a gas chromatograph coupled with a mass spectrometer (GC-MS). The evaluation of antimicrobial characteristics was carried out by determining the growth inhibition zone implementing the Agar method, the minimum inhibition concentration (MIC), and the minimum bactericidal/fungicidal concentration (MFC/MBC) utilizing liquid dilution culture. Results The results indicated that the highest yield belonged to the EO of D. kotschyi at %2.6 (w/w). In this EO there were citral (%25.44), neral (%20.87), α-pinene (%14.48), trans-geranic acid methyl ester (%9.74), and D-limonene (%6.87). Moreover, H. incanus had the dominant compounds (-)-Spathulenol (%12.61), caryophyllene (%10.00), linolenic acid (%8.54), 1,8-cineole (%5.95), palmitic acid (%5.35), and α-cadinol (%5.17). The largest diameter of growth inhibition zone belonged to the H. incanus EO against the Gram-positive bacteria S. pyogenes (~17.67mm). The strongest inhibition activities in the form of growth inhibition diameter exhibited by the D. kotschyi EO were against the Gram-negative bacteria S. paratyphi-A serotype (~ 12 mm), K. pneumoniae, and Sh. dysenteriae (~ 11 mm) which was significant compared to the Gram-positive rifampin (~ 8 mm). Conclusions It can be seen that these species are new chemotypes with special and novel chemical compounds which can potentially be used to manufacture natural antibiotics against some bacterial strains.

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“…The antibacterial activity of ethanolic extract may be related to the high level of known components with antibiotic properties as phytol against E. coli, S. typhimurium, S. aureus, antifungicidal viz. C. albicans, A. niger [23][24][25][26]; squalene against S. aureus [27]; β-amyrin against B. subtilis, S. aureus, E. coli, S. typhimurium, in total they make up 15.44 % [28,29].…”

Section: Resultsmentioning

confidence: 99%

“…Their secondary metabolites often have multiple effects and can be widely used. Apparently the antioxidant components of ethanolic extract, capable of scavenging free radicals, were β-amyrin [28,29], squalene [39], phytol [24][25][26], scopoletin [40,41]. These compounds reached 19.62 % of the total amount.…”

Section: Resultsmentioning

confidence: 99%

Phytochemical Contents, Antimicrobial and Antioxidant Properties of Gnaphalium uliginosum L. Ethanolic Extract and Essential Oil for Agricultural Uses

et al. 2019

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Gnaphalium uliginosum L. (Asteraceae) is widely used in phytotherapy and has a potential for agricultural utilization. The ethanolic extract was obtained from the maceration of air-dried plants, and the extract was then filtered and concentrated using a rotary evaporator. The essential oil was pressed from freshly harvested and crushed, aerial part of plants. The chemical compositions of ethanolic extract and essential oil of G. uliginosum L. (EOG) were investigated using gas chromatography/mass spectrometry (GC/MS). Nine constituents accounted for 77.3 % of the total detected components were determined at the ethanolic extract with a high proportion of sterols 42.8%, fatty acids 24.1 %, triterpenes 14.4 %. Twenty constituents were identified in essential oil of G. uliginosum L.; with α-pinene and estragole accounting for 54.0 %. The ethanolic extract was found to have a moderate antimicrobial activity (MIC values varied from 125 to 500 μg/mL), for S. aureus, B. cereus and A. solani significant activity (less than 62.5 μg/mL). The essential oil was found to have a moderate (MICs 500-1000 μg/mL) and strong activities (31.3-250 μg/mL). The antioxidant activity was evaluated using chemiluminescent assay. The ethanolic extract of G. uliginosum L. acted as a medium-strength antioxidant at concentrations of less than 0.1 mg/mL. The essential oil made be regarded as a weak strength antioxidant.

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Phytol – A biosurfactant from the aquatic weed Hydrilla verticillata

Cited by 17 publications

References 31 publications

GC–MS profiling and antibacterial activity of Solanum khasianum leaf and root extracts

GC–MS profiling and antibacterial activity of Solanum khasianum leaf and root extracts

A GC-MC analysis of chemical compounds and identification of the antibacterial characteristics of the essential oil of two species exclusive to Iranian habitats: New chemotypes

Phytochemical Contents, Antimicrobial and Antioxidant Properties of Gnaphalium uliginosum L. Ethanolic Extract and Essential Oil for Agricultural Uses

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