Phytochemistry and Pharmacological Studies ofCitrus macroptera: A Medicinal Plant Review

Abstract

Citrus macroptera (family Rutaceae), commonly known as Sat Kara, is a pharmacologically diverse medicinal plant. Various parts of this plant, specifically fruit, have an immense range of medicinal uses in folk medicine directed for a number of ailments. A plethora of active phytochemical constituents of this plant have been revealed so far, namely, limonene, beta-caryophyllene, beta-pinene, geranial edulinine, ribalinine, isoplatydesmine, and so forth. Several studies demonstrated the exploration of pharmacological potential of various parts such as fruits, leaves, and stems of C. macroptera as antioxidant, cytotoxic, antimicrobial, thrombolytic, hypoglycemic, anxiolytic, antidepressant, cardioprotective, and hepatoprotective. Furthermore, inhibition of in vitro α-amylase, inhibition of paracetamol induced hepatotoxicity, and potentiation of brain antioxidant enzyme are also ascertained. In present review, comprehensive study focused on knowledge regarding several phytopharmacological activities of Citrus macroptera has been described.

A systematic review on the neuroprotective perspectives of beta‐caryophyllene

“…Search for medicines to relieve pain and cure various neurological diseases is an ancient (up to 60,000 years ago) process and is still ongoing (Summer, ). Plants are a source of numerous bioactive compounds with pharmaceutical importance, which also have both chemopreventive and therapeutic effects against various ailments (Aktar & Foyzun, ). Use of medicinal plants and/or plant‐derived natural products is gaining interest from scientists owing to their safety profile, higher efficacy, and age‐old use in various traditional practices.…”

Screening of Antibacterial, Thrombolytic, Membrane Stabilizing, Anti-inflammatory and Antitumor Activity of <i>Citrus assamensis</i> Leaf Extracts

“…A number of research works have been conducted to discover the plants and natural food sources and their supplements having antithrombotic effect and there is indication that consuming such food leads to prevention of coronary events and stroke [60][61][62][63][64][65][66]. From the literature review it was also observed that the C. hystrix (Leaf), C. macroptera (Fruit), C. sinensis (Peel oil) has a significant thrombolytic effect [67][68][69][70]. From the present study, it can be concluded that the different leaf extracts of C. assamensis is able to lyse clot by disrupting the fibrinogen and fibrin…”

Green Synthesis of Iron Nanoparticles for Investigation of Biofilm Inhibition Property

“…[26] Citrus macroptera (CM), a rarely available fruit in North-Eastern part of India, has huge medicinal values. [35][36][37] Here, we report the green synthesis of FeNPs using Citrus mercroptera (CM) fruit extract and the biofilm inhibition property of such particles (CM-FeNPs) against a nosocomial infection causing bacteria Pseudomonas aeruginosa (P. aeruginosa). The study also includes two interesting findings: one, the test of CM-FeNPs in combination with azithromycin (AZI), a conventional antibiotic, in order to evaluate their combo effect in improving biofilm inhibition and second, the in silico interactions of biomolecules present in C. macropetera fruit extract with bacterial proteins, associated to biofilm formation.…”