Phytochemical screening of Leucaena leucocephala leaf essential oil and its antibacterial potentials

Abstract

Objective: The study aimed to identify the phytochemical composition of Leucaena leococephala leaf and evaluate the antimicrobial potential of the essential oil from the leaf. Material and Methods: The sample was subjected to Clevenger apparatus to extract the oil. The essential oil was characterized by chromatography method (GC-MS). The GC-MS was performed on Perkin Elmer gas chromatography model Clarus 680 equipped with HP-5 fused capillary column (5%) phenylmethyl polysiloxane stationary phase with 30m length, 0.25µm of film thickness and 0.25oc and 280oc respectively. Antibacterial activity using Agar Disc Method. Result: The result obtained from the GC-MS presented thirty phytochemicals of which Neophytadiene (9.48%), Octadecane (3.15%), 1-Octadecyne (3.85%), Phytol (52.51%) and Hexacosane (7.26%) are major. The antibacterial potential activities were observed in various ways with zone of inhibition diameters ranging from 0.70±0.00mm to1.27±0.06mm for staphylococcus aureus and Klebsielia pneumonia respectively among the six-concentration selected (25, 50, 100, 250, 500, and 1000ppm). Conclusion: It is investigated in this present studies that Leucaena leococephala essential oil can be utilized against the management of antibacterial diseases particularly Klebsielia pneumonia and Staphylococcus aureusas well as used in the Pharmaceutical and Cosmetics industry.

The Volatile Organic Compounds of Streptomyces spp.: An In-Depth Analysis of Their Antifungal Properties

“…As expected, 2-methylisoborneol and geosmin were detected. Likewise, different compounds with antimicrobial activity were detected, such as furanones, dimethyl disulfide, 2,6,6-trimethyl-1-Cyclohexene-1-acetaldehyde, and muurola derivatives [53,57,58]. It is worth highlighting the production of caryophyllenyl alcohol, identified in several samples in both media and associated with several applications in cosmetics and derivatives in the drug industry (hypolipidemic, anti-inflammatory properties [59][60][61][62].…”

“…2,6,6-Trimethyl (beta-homocyclocitral)1-cyclohexene-1-acetaldehyde [51] and 1,3,3trimethyl-tricyclo [2.2.1.0(2,6)] heptane (cyclofenche) [52] are compounds with antifungal activities present in essential oils. Similarly, 4,8-dimethylnona-1,3,7-triene is also described as a monoterpene part of plant essential oils with antifungal activities [53]. 3-Octanone has been described as an antifungal cetone [54].…”

Current State of Knowledge Regarding WHO High Priority Pathogens—Resistance Mechanisms and Proposed Solutions through Candidates Such as Essential Oils: A Systematic Review

“…Propolis extract has been shown to exhibit antimicrobial activity against ciprofloxacinsensitive and ciprofloxacin-resistant N. gonorrhoeae strains, in a study by Vică et al; depending on the harvesting region, the extracts presented with various inhibition zone diameters and MICs [130] (Appendix B, Table A5). Umaru et al studied the effect of Molineria capitulate fruit EO on various pathogens and showed that both M. capitulate EO and its major component, myrcene, displayed antimicrobial activity against N. gonorrhoeae strains [131]. Soliman et al investigated the antimicrobial properties of two guava (Psidium spp.)…”

Potential of Syzygnium polyanthum as Natural Food Preservative: A Review

“…Sygzinium polyanthum with its synonym Eugenia Polyantha contain active compounds as antioxidants [121]. Compounds in S. polyanthum acting as antioxidants are pyrogallol, gallic acid, myrecitin, farnesol, phytol, and tocopherol [122,123]. The antioxidant compounds in S. polyanthum are shown in Figure 5.…”