Phytochemical screening, antioxidant, antifungal potentials of Acacia auriculiformis floral Scent composition

Samling, Benedict; Umaru, Isaac John

doi:10.15406/japlr.2018.07.00296

Cited by 6 publications

(4 citation statements)

References 7 publications

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“…Phytol is a well-known antiinflammatory agent (28). Neophytadiene has been reported to have an inhibitory effect against several microbes (29). Di-methyl palmitamine is also antioxidant along with antifungal properties (30).…”

Section: Gc-ms Of Methanolic Extract Of the Leaves Of Micropropagated And Mother Plantmentioning

confidence: 99%

Complete plant regeneration of Valeriana wallichii DC. on auxin enriched medium and phytochemical analysis

et al. 2020

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Valeriana wallichii DC. (Valerianaceae) is a well-known medicinal herb distributed in Northwest Himalayas. The herb is utilized in the treatment of numerous ailments and diseases such as diarrhoea, diabeties, gastrospans, ulcer and wound healing, etc. Overexploitation, especially collection of rhizomes on a large scale for the medicinal purpose has significantly declined the availability of the herb in natural stands. Hence, there is a requirement of development of cultivation practices and protocol for mass propagation to achieve sustained utilization along with conservation of the species. In the present study, in-vitro culture of nodal segments on MS+2iP+IAA+2,4-D and MS+2iP+IAA+NAA resulted in multiple shoot induction along with regeneration of in-vitro roots on the same medium making the protocol cost-effective, efficient and comparatively less time-consuming. Moreover, the regeneration of adventitious roots from regenerated shoots enhanced the total number of plants obtained per explant as shoots with adventitious roots were individually excised and were transferred to natural conditions through the process of acclimatization. GC-MS analysis of a methanolic extract of leaves of the mother plant and micropropagated plant revealed the presence of 37 and 36 phytocompounds respectively. Phytocompounds including eucalyptol, neophytidiene, hexadecenoic acid, dimethyl palmitamine were identified to be present in the leaves of both mother and micropropagated plants whereas other compounds such as eicosyne, lilial, behenic alcohol were confined to be present in extract prepared from leaves of mother plant. Similary some phytocompounds (phytol, vinicizer, retinol) were detected in methanolic extract prepared from leaves of micropropagated plants.

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Section: Gc-ms Of Methanolic Extract Of the Leaves Of Micropropagated And Mother Plantmentioning

confidence: 99%

Complete plant regeneration of Valeriana wallichii DC. on auxin enriched medium and phytochemical analysis

et al. 2020

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“…1,3-Cyclohexadiene, 5-(1,5-dimethyl-4-hexenyl)-2-methyl-, [S-(R*,S*)]- was identified in the methanol extract of Zingiber officinale , and this compound had pharmacological properties such as antioxidant, anti-inflammatory, and antinociceptive activities [ 53 ]. 1-Octadecanesulphonyl chloride was previously isolated from the volatile floral extract of Acacia auriculiformis, which exhibited antioxidant and antifungal activity [ 54 ]. Oxalic acid, allyl pentadecyl ester was identified in the methanol extract of red alga Laurencia brandenii , which showed anti-pest, antimicrobial, termiticidal, and maggoticidal activity [ 55 ].…”

Section: Resultsmentioning

confidence: 99%

Breynia cernua: Chemical Profiling of Volatile Compounds in the Stem Extract and Its Antioxidant, Antibacterial, Antiplasmodial and Anticancer Activity In Vitro and In Silico

et al. 2023

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Breynia cernua has been used as an alternative medicine for wounds, smallpox, cervical cancer, and breast cancer. This plant is a potential source of new plant-derived drugs to cure numerous diseases for its multiple therapeutic functions. An in vitro study revealed that the methanol extract of B. cernua (stem) exhibits antioxidant activity according to DPPH and SOD methods, with IC50 values of 33 and 8.13 ppm, respectively. The extract also exerts antibacterial activity against Staphylococcus aureus with minimum bactericidal concentration of 1875 ppm. Further analysis revealed that the extract with a concentration of 1–2 ppm protects erythrocytes from the ring formation stage of Plasmodium falciparum, while the extract with a concentration of 1600 ppm induced apoptosis in the MCF-7 breast cancer cell line. GC–MS analysis showed 45 bioactive compounds consisting of cyclic, alkyl halide, organosulfur, and organoarsenic compounds. Virtual screening via a blind docking approach was conducted to analyze the binding affinity of each metabolite against various target proteins. The results unveiled that two compounds, namely, N-[β-hydroxy-β-[4-[1-adamantyl-6,8-dichloro]quinolyl]ethyl]piperidine and 1,3-phenylene, bis(3-phenylpropenoate), demonstrated the best binding score toward four tested proteins with a binding affinity varying from −8.3 to −10.8 kcal/mol. Site-specific docking analysis showed that the two compounds showed similar binding energy with native ligands. This finding indicated that the two phenolic compounds could be novel antioxidant, antibacterial, antiplasmodial, and anticancer drugs. A thorough analysis by monitoring drug likeness and pharmacokinetics revealed that almost all the identified compounds can be considered as drugs, and they have good solubility, oral bioavailability, and synthetic accessibility. Altogether, the in vitro and in silico analysis suggested that the extract of B. cernua (stem) contains various compounds that might be correlated with its bioactivities.

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“…Other investigators have also reported on the variable antifungal activity of plant extracts. The flower of Acacia auriculiformis was analyzed against Aspergillus niger and Candida tropicallis and its antifungal activity was confirmed at 1000 ppm concentration (Samling et al, 2018). Kim et al (2004) testified that 33 (18%) out of 183 plant species displayed strong in vivo antifungal properties against at least one of six plant pathogenic fungi.…”

Section: Discussionmentioning

confidence: 99%

Comparative Study on the Antimicrobial Activity in Various Solvent Extracts of Garcinia gummi-gutta (L.) Roxb and Solanum betaceum Cav. Fruits Against Major Fish Pathogens

M.T.¹,

Nisha²,

Preethi³

et al. 2022

IJZI

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The present study aimed to evaluate the antimicrobial activity of the extracts from the fruits of Garcinia gummi-gutta and Solanum betaceum using the standard Agar well diffusion method. Three concentrations (25, 50,and 75 µl/ml) of various extracts such as aqueous, ethanol, petroleum ether, and chloroform were tested against six fish pathogens such as Aeromonas hydrophila, Vibrio cholerae, Streptococcus agalactia, Streptococcus iniae Pseudomonas aeruginosa, and Klebsiella pneumoniae. Amoxiclav 10 mcg was used as the positive control (Disc). Three major fungal species Aspergillus niger, Aspergillus flavus, and Candida albicans were used to determine the fruit extracts' antifungal activity at three different concentrations (25, 50, 100 µl/ml). Amphotericin B (100 units) was used as a positive control. Both plant extracts showed dose-dependent antimicrobial activity against the tested pathogens. The crude ethanol and petroleum ether extracts of G. gummi-gutta and S. betaceum displayed more potential against all strains at higher concentrations. However, G. gummi-gutta showed better efficacy against microbes when compared to S. betaceum. The findings of present study will be valuable for future identification, quality control, and pharmacological studies of natural chemicals derived from these plants especially in aquaculture.

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Phytochemical screening, antioxidant, antifungal potentials of Acacia auriculiformis floral Scent composition

Cited by 6 publications

References 7 publications

Complete plant regeneration of Valeriana wallichii DC. on auxin enriched medium and phytochemical analysis

Complete plant regeneration of Valeriana wallichii DC. on auxin enriched medium and phytochemical analysis

Breynia cernua: Chemical Profiling of Volatile Compounds in the Stem Extract and Its Antioxidant, Antibacterial, Antiplasmodial and Anticancer Activity In Vitro and In Silico

Comparative Study on the Antimicrobial Activity in Various Solvent Extracts of Garcinia gummi-gutta (L.) Roxb and Solanum betaceum Cav. Fruits Against Major Fish Pathogens

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