Phytochemical Screening and Pharmacological Evaluation of Different Extracts of Plant Casearia Tomentosa Leaves

Tyagi, Ritu; Shukla, Alok Kumar; Shukla, Rishi

doi:10.22159/ijpps.2017v9i4.16816

Cited by 4 publications

(5 citation statements)

References 18 publications

(19 reference statements)

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“…The presence of secondary metabolites including alkaloids, saponins, flavonoids in the plant may be are responsible for its potential antibacterial activity [17]. The reason for a greater activity of hexane extract could be attributed to the non-polar nature of the solvent which may be responsible for the extraction of a wide range of phytoconstituents that potentiates the activity of extract [18].…”

Section: Discussionmentioning

confidence: 99%

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Impact of Solvent Types on Antimicrobial Activities of Root Extract of Caesaria Tomentosa

Angle¹,

Sardessai²

2019

Int J Pharm Pharm Sci

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Objective: The study deals with the antimicrobial activity of five solvent extracts of roots of Caesaria tomentosa against seven microorganisms: two gram-positive (Staphylococcus aureus and Bacillus subtilis), three gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa and Salmonella typhimrium) and two fungal strains (Candida albicans and Aspergillus niger). Methods: Roots of C. tomentosa were extracted with different solvents(n-hexane, ethanol, chloroform, acetone and water) and were subjected to antibacterial as well as antifungal screening by Well Diffusion Method. The Minimum Inhibitory Concentration(MIC) was also performed by two-fold dilution. Results: The maximum inhibition zone at 50μg/ml concentration of n-hexane was 32 mm. These indicate that some active substances in C. tomentosa dissolved in varying degrees in the five solvents. The MIC for n-hexane was 1.6 μg/ml for S. aureus leading to a conclusion that the n-hexane extract was found to be the most potent. Conclusion: All extracts were very effective against S. aureus. As for the solvents, the n-hexane extract had the best inhibitory effect among five solvents tested.

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Section: Discussionmentioning

confidence: 99%

“…The literature survey revealed that C. tomentosa is still an under explored species [5]. The aim of this study was to study the impact of solvent types on antimicrobial activities of root extract of C. tomentosa.…”

Section: Introductionmentioning

confidence: 99%

Impact of Solvent Types on Antimicrobial Activities of Root Extract of Caesaria Tomentosa

Angle¹,

Sardessai²

2019

Int J Pharm Pharm Sci

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“…A study of the antioxidant activity of the leaves of the Casearia tomentosa plant revealed that it had a high antioxidant property [10] . Different extracts of the leaves of the plant Casearia tomentosa have been found to be a possible natural source of antioxidant, antidiabetic, and antibacterial agents in the current investigation [9] . The goal of this study is to see if Casearia tomentosa Roxb's bark and leaf extracts have antibacterial and antioxidant properties.…”

Section: Pharmacological Activitiesmentioning

confidence: 98%

“…The phytochemical screening and various pharmacological properties of several extracts of the leaves of the plant Casearia tomentosa were examined in this study. Alkaloids, flavonoids, carbohydrates, glycosides, protein, and other phytochemicals are found in Casearia tomentosa leaves [9] . Preliminary phytochemical analysis of this plant's extract indicated the presence of active phytoconstituents such as steroids, phytosterol, terpenoids, fats and oils, and other phytoconstituents.…”

Section: Phytochemical Constituentsmentioning

confidence: 99%

Casearia tomentosa Roxb: A comprehensive review on botany, traditional uses, phytochemistry and pharmacology

Talukdar¹,

Mannan²,

Nijhu³

et al. 2021

J Pharmacogn Phytochem

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Casearia tomentosa is a member of the Salicaceae family, which is also known as Chilla. Different portions of Casearia tomentosa have traditionally been used to treat ulcers, dropsy, fissures, malarial fever, tonsillitis pain, wounds, and plaster. This plant's extract indicated the presence of alkaloids, flavonoids, carbohydrates, glycosides, protein, steroids, phytosterol, terpenoids, lipids, and oils. The leaves have been shown to be a natural source of antioxidants, antidiabetic, and antibacterial properties. The available information was gathered from scientific databases using a keyword search in "Google Scholar," "Pub med," "Science direct," "Springer Link," "Wiley" and "Sci finder". Moreover, books were recommended for plant data and synthetic structure. Nonetheless, pharmacological information is very restricted. Subsequently, the point of this review is to give an extensive information of the botany, phytochemistry and pharmacology of Casearia tomentosa and to feature the holes in our insight for future exploration openings.

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“…plant is exhibits various pharmacological activities reported as analgesic, antipyretic, antiinflammatory [5], antispasmodic [6], anthelmintic, antimicrobial activity [7], and antioxidant [8,9] as well. Due to the presence of several active phytoconstituents [10], this synthesizes primary and secondary metabolites having benefits in traditional system of medicine [11].…”

Section: Introductionmentioning

confidence: 99%

Screening of Phytochemicals and in Vitro Antidiabetic Activity of Bauhinia Racemosa Lam. Leaves

Gawade¹,

Farooqui²

2018

Asian J Pharm Clin Res

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Objective: In this study, the leaves of medicinal plant Bauhinia racemosa Lam. with different pharmacological activities were subjected to phytochemical screening and assessment of their in vitro inhibitory potential with porcine pancreatic α-amylase enzyme to treat and management of diabetes.Methods: Plant leaves were extracted sequentially with ethanol solvent. A modified 3,5-dinitrosalicylic acid method was adopted to screen α-amylase inhibition assay. The ethanol extract was analyzed qualitatively and gas chromatography-mass spectrometry analysis technique for the active phytoconstituents according to the standard protocols.Results: A phytochemical screening of leaves extract reveals the presence of carbohydrate, alkaloids, saponin, glycosides, steroids, tannins, flavonoids, triterpenoid, and phenolic compounds. The ethanol extract reported inhibition of α-amylase enzyme activity at IC 50 value 61.72 ± 0.03 µg/mL and acarbose as a standard drug at IC 50 value 28.07 ± 0.02 µg/mL. Conclusion:The results of the study indicate that B. racemosa Lam. leaves contain some of bioactive phytochemicals might to be exhibiting in vitro antidiabetic activity, which was leading to decreases the rate of starch digestion.

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Phytochemical Screening and Pharmacological Evaluation of Different Extracts of Plant Casearia Tomentosa Leaves

Cited by 4 publications

References 18 publications

Impact of Solvent Types on Antimicrobial Activities of Root Extract of Caesaria Tomentosa

Impact of Solvent Types on Antimicrobial Activities of Root Extract of Caesaria Tomentosa

Casearia tomentosa Roxb: A comprehensive review on botany, traditional uses, phytochemistry and pharmacology

Screening of Phytochemicals and in Vitro Antidiabetic Activity of Bauhinia Racemosa Lam. Leaves

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