Phytochemical, Phytotherapeutical and Pharmacological Study of Momordica dioica

Abstract

Momordica dioica is a perennial, dioecious, cucurbitaceous climbing creeper (commonly known as kakrol, spiny gourd or teasle gourd). It is native to Asia with extensive distribution in India and Bangladesh. It is used not only as preventive and curative agent for various diseases but also as vegetable with a significant nutritional value over thousands of years. This review aims to take an attempt to evaluate the phytochemical, ethnobotanical, phytotherapeutical and pharmacological properties of kakrol according to the view of traditional medicinal plant based treatment including ayurveda along with recent scientific observations. Kakrol is considered as an underutilized vegetable, although having significant presence of certain compounds containing higher nutritional value than many frequently consumed vegetables. Moreover, as a traditional medicinal plant, it is still potential for its phytochemical components that increase the demand of further extensive evaluation to justify its other therapeutical roles. Therefore, this effort will be helpful to researchers who interested to disclose the unjustified phytotherapeutical role of Momordica dioica.

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“…Similarly methanol and aqueous extract of its fruit pulp have neuroprotective activities in-vivo 45 . Claimed that Phenolic, flavonoids in Phaseolus vulgaris are helpful in preventing depression as well as having the ability to remove ROS 46 .…”

Nephroprotective Activity of the Ethnomedicinal Plants Caesalpinia Bonduc and Momordica Dioica From Ne India Against Cisplatin Induced Chemotherapeutic Toxicity

“…The extracts of Momordica dioica and Caesalpinia bonduc were subjected to preliminary phytochemical analysis [14], testing for the detection of different chemical groups of compounds. Air-dried and powdered plant materials were screened for the presence of, total phenols and flavonoids.…”

“…Phenolic compounds are plant secondary metabolites produced either from phenylalanine or from its precursor shikimic acid [14]. The phenolic compounds are capable of the direct chain breaking antioxidant action by free radical scavenging.…”

Sex-oriented research on dioecious crops of Indian subcontinent: an updated review

“…The M. dioica has several medicinal uses (Talukdar and Hossain 2014). Dried fruit powder produces a powerful errhine effect when applied into the nostrils.…”

“…The tubers of the teasle gourd act as antihelminthic, spermicidal, and antifertility as well as abortifacient agent. Beside these, it has antioxidant, analgesic, nephroprotective, neuroprotective, antiallergic, antiulcer, anticancer, antimicrobial, antimalarial, hepatoprotective, antihepatotoxic, antiedemic and insecticidal properties (Talukdar and Hossain 2014). Narasimhan et al (2005) showed antifeedant activity of M. dioica against Spodoptera litura and the seed oil of M. dioica could be used as grain protectant against Callosobruchus chinensis (Mishra et al 2006).…”