PHYTOCHEMICAL INVESTIGATION AND IN VITRO ANTIFUNGAL ACTIVITY OF ESSENTIAL OIL FROM THE RHIZOME OF BERGENIA STRACHEYI (Hook.f. &amp; Thomson) Engl.

Kumar, Pawan; Javed, Mohammad S.; Tewari, Amit; Bisht, Kavita

doi:10.22270/jddt.v7i1.1365

Cited by 3 publications

(2 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Previous studies demonstrated that Bergenia stracheyi had been widely used by traditional Indian, Nepalese and Chinese medicine systems for the treatment of bladder and kidney stones and several other diseases (52)(53)(54). Similarly, the present study recorded Bergenia stracheyi with cent fidelity level, used against kidney stones that release stones from the kidney, yet no medical therapy has been performed.…”

Section: Important Ethnomedicinal Speciesmentioning

confidence: 99%

Herbal remedies used for the management of urolithiasis in Abbottabad, Northern Pakistan

et al. 2021

View full text Add to dashboard Cite

The current study was performed to evaluate the ethnobotanical uses of medicinal plants to treat and prevent kidney diseases, especially urolithiasis in the Abbottabad region, Northern Pakistan. Field surveys were conducted from 2014–2016 in various rural and tribally dwelled hilly areas like Ayubia National Park, Sherwan and Thandiani. Ethnobotanical information about the medicinal plants employed to treat urinary ailments was obtained from well-informed sources like local healers (hakims) and residents (men/women), who had vast knowledge of local plants uses. The questionnaire method was adopted to record the information and queries were made to verify the information. Informed consent was obtained from each informant before conducting the interview process. Quantitative ethnobotanical indices were calculated for each recorded species. Correlation analysis between the RFC, UV and FL% was tested by Pearson’s correlation, SPSS (ver. 16). A total of 38 plant species belonging to 27 families were being used in the study area to treat Urolithiasis or kidney stone diseases. Asteraceae was the most dominant family with 5 species. Local people used different methods of preparation for different plant parts; among them, decoction was the popular and dominant way of preparation (52.6%), followed by powder (18.4%), extracts (15.7%), juice (7.8%) and cooked (5.2%). The highest UV was recorded for Rumex acetosa L. (1.14) followed by Agrimonia eupatoria L. (1.1), Equisetum ramosissimum Desf. (1.05), Aerva lanata L. (1.04), Eclipta alba Hassak. (1.03). Moreover, twenty-three species were recoded with above 50% Fidelity level. It was found that most of the plant species (16 species) were explicitly used to remove kidney stones. All the obtained data about the ethnomedicinal uses of plants to treat urinary tract ailments are alphabetically categorized to their botanical name/family, local name, phytoconstituents, dosage and route of administration, along with quantitative indices value. All the collected ethnomedicinal plants require a thorough scientific investigation for isolation, identification, biochemical assays, toxicities and evaluation of pharmacological activities of the phytoconstituents, especially of the plants recorded with a high-fidelity level before their usage in clinics.

show abstract

Section: Important Ethnomedicinal Speciesmentioning

confidence: 99%

Herbal remedies used for the management of urolithiasis in Abbottabad, Northern Pakistan

et al. 2021

View full text Add to dashboard Cite

show abstract

“…The main chemical constituents that are reported so far from B. stracheyi include bergenin or its derivatives [10], terpenes [11], and flavonoids [12]. Previously, a few traditional separation methods such as HPLC [13], silica gel column chromatography [10, 14], and ultra‐high‐performance liquid chromatography coupled to hybrid linear ion trap triple quadrupole MS [15] have been employed for the isolation of constituents from B. stracheyi .…”

Section: Introductionmentioning

confidence: 99%

Separation of constituents from Bergenia stracheyi (Hook. F. & Thoms.) Engl. by high‐speed countercurrent chromatography with elution mode and its antidiabetic and antioxidant in vitro evaluation

Hou

Ali

Zhao

et al. 2020

J of Separation Science

View full text Add to dashboard Cite

Diabetes, a metabolic disorder, is caused by a high blood sugar level. Diabetes is an increasing health issue and search for potent antidiabetic agents is desirable. Owing to its ethnomedicinal value, the Himalayan perennial herb Bergenia stracheyi (Hook. f. & Thoms.) Engl. (Saxifragaceae Juss) is used to treat diabetes. Herein, an efficient high‐speed countercurrent chromatography with elution mode is reported for separation of active compounds from B. stracheyi. In current investigation, six main compounds including β‐arbutin (1), bergenin (2), 6‐O‐galloylarbutin (3), gallic acid (4), 11‐O‐galloylbergenin (5), and (‐)‐epicatechin 3‐O‐gallate (6) with above 95% purity were efficiently separated in a single run using biphasic tert‐butyl methyl ether/n‐butanol/methanol/water (1:3:1:5, v/v/v/v) solvent system. The structures of these compounds were characterized using spectral techniques and compared with the literature. Antidiabetic and antioxidant activities evaluation of the study samples showed that β‐arbutin (1) and 6‐O‐galloylarbutin (3) have a significant protective effect, especially at high dose against hydrogen peroxide induced oxidative injury. Our results might help further in‐depth phytochemical and biological evaluation studies in search of potent antidiabetic compounds from B. stracheyi.

show abstract

Bergenia ciliata as antibacterial agent

Shah

Khan

et al. 2020

GSC Biol. and Pharm. Sci.

View full text Add to dashboard Cite

The search for alternatives to combat antibiotics has been increased due to the upsurge in cases of antibiotic-resistant pathogens that has become a global phenomenon which threatens the human health. Medicinal plants provide multiple health benefits because these plants contain bioactive phytochemicals that are used in medicines as alternatives to various ailments of human beings. Bergenia ciliata is a perennial herb belongs to the family Saxifragaceae that consists of about 30 genera and 580 species worldwide. It has large, evergreen and leathery leaves with the pink to dark purple flowers and has various traditional and modern medical uses. This plant is considered is one of the most effective antibacterial agents. The present review emphasizes the antibacterial potential of Bergenia ciliata by compiling various researches and fragmented information. The most important phytochemicals derived from Bergenia ciliata launched on the pharmaceutical market are also discussed. This attempt will help the researchers to develop and synthesize new antibacterial drugs from Bergenia ciliata against drug-resistive pathogens.

show abstract

PHYTOCHEMICAL INVESTIGATION AND IN VITRO ANTIFUNGAL ACTIVITY OF ESSENTIAL OIL FROM THE RHIZOME OF BERGENIA STRACHEYI (Hook.f. & Thomson) Engl.

Cited by 3 publications

References 4 publications

Herbal remedies used for the management of urolithiasis in Abbottabad, Northern Pakistan

Herbal remedies used for the management of urolithiasis in Abbottabad, Northern Pakistan

Separation of constituents from Bergenia stracheyi (Hook. F. & Thoms.) Engl. by high‐speed countercurrent chromatography with elution mode and its antidiabetic and antioxidant in vitro evaluation

Bergenia ciliata as antibacterial agent

Contact Info

Product

Resources

About