Phyto-fabrication, characterization, and biomedical activity of silver nanoparticles mediated from an epiphytic plant Luisia tenuifolia Blume

Narayanan, Mathiyazhagan; Deepika, M; Ma, Ying; Nasif, Omaima; Alharbi, Sulaiman Ali; Ramalingam, Srinivasan

doi:10.1007/s13204-021-02022-z

Cited by 6 publications

(1 citation statement)

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“…To cope with this statement, the plant (Ferula asafoetida)-mediated silver nanoparticle (AgNPs) was used in this study. Since, genus of this plant has been recognized as possess significant quantity of pharmaceutically valuable phytochemicals as well as which can synthesize the AgNPs, and synthesized nanoparticles may possess remarkable biomedical application [31]. Hence, this research was performed to evaluate the antioxidant and anticancer activity of previously synthesized and characterized plant-mediated AgNPs.…”

Section: Introductionmentioning

confidence: 99%

An Assessment of Anticancer Activity (MCF-7) and Free Radicals Scavenging Potential of Ferula Asafoetida Synthesized AgNPs through In Vitro Analyses

Thành

Chinnathambi

Alahmadi

et al. 2022

Journal of Nanomaterials

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Nanomaterials are increasingly being used in pharmaceutical industry to treat a variety of disorders and diseases. Hence, the aim of this research was to evaluate their antioxidant and anticancer activity of presynthesized and characterized plant-based AgNPs against ferric, DPPH, H2O2, and ABTS free radicals and MCF-7 cell line. Interestingly, the antioxidants assay results revealed that the increased concentration (100 μg mL-1) of AgNPs has remarkable antioxidant ability on ferric (78.20%), DPPH (89.61%), H2O2 (82.34%), and ABTS (67.95%) free radicals. These scavenging activities were almost close to the free radicals scavenging ability of vitamin C (ascorbic acid). Similarly, test AgNPs showed considerable cytotoxicity (83.15%) against MCF-7 cell line, and it was partially comparable with the cytotoxicity activity (91.35%) of positive control (Doxorubicin). These findings indicate that plant-mediated AgNPs have significant antioxidant and anticancer activity, and thus may be considered for biomedical applications pending the results of some in vivo experiments.

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Section: Introductionmentioning

confidence: 99%