Physiological Effects and Human Health Benefits of Hibiscus sabdariffa: A Review of Clinical Trials

Montalvo‐González, Efigenia; Villagrán, Zuamí; Gonzalez-Torres, Yesica Sughey; Iñiguez-Muñoz, Laura Elena; Isiordia-Espinoza, Mario Alberto; Ruvalcaba-Gómez, José Martín; Arteaga-Garibay, Ramón Ignacio; Acosta, José Luís; González-Silva, Napoleón; Anaya-Esparza, Luis Miguel

doi:10.3390/ph15040464

Cited by 28 publications

(23 citation statements)

References 108 publications

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“…The T. speciosum extract presented a slight higher TPC value (640 mg EAG/g) [18], and H. rosa-sinensis L. showed a lower value of antioxidant activity (DPPH 145 ± 3 mg TE/100 g DW) [21] than the extract of H. acetosella flowers. Several studies both in vitro and in vivo have shown that extracts of Hibiscus present a potent antioxidant effect due to its strong scavenging effect on reactive oxygen and free radicals [19,22]. The results found herein contribute to stimulating the consumption of edible flowers as a functional food as well as stimulating their use as sources of natural antioxidants by the food industry [23].…”

Section: Physicochemical Characterization Centesimal Composition and ...mentioning

confidence: 61%

Hibiscus acetosella: An Unconventional Alternative Edible Flower Rich in Bioactive Compounds

et al. 2023

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The interest in the consumption of edible flowers has increased since they represent a rich source of bioactive compounds, which are significantly beneficial to human health. The objective of this research was to access the bioactive compounds and antioxidant and cytotoxic properties of unconventional alternative edible flowers of Hibiscus acetosella Welw. Ex Hiern. The edible flowers presented pH value of 2.8 ± 0.00, soluble solids content of 3.4 ± 0.0 °Brix, high moisture content of about 91.8 ± 0.3%, carbohydrates (6.9 ± 1.2%), lipids (0.90 ± 0.17%), ashes (0.4 ± 0.0%), and not detectable protein. The evaluation of the scavenging activity of free radicals, such as 2,2-diphenyl-1-picryl-hydrazyl (DPPH) and 2,2’-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), of the flower extract was better than the results observed for other edible flowers (507.8 ± 2.7 μM TE and 783.9 ± 30.8 μM TE, respectively) as well as the total phenolic composition (TPC) value (568.8 ± 0.8 mg GAE/g). These flowers are rich in organic acids and phenolic compounds, mainly myricetin, and quercetin derivatives, kaempferol, and anthocyanins. The extract showed no cytotoxicity for the cell lineages used, suggesting that the extract has no directly harmful effects to cells. The important bioactive compound identified in this study makes this flower especially relevant in the healthy food area due to its nutraceutical potential without showing cytotoxicity.

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Section: Physicochemical Characterization Centesimal Composition and ...mentioning

confidence: 61%

Hibiscus acetosella: An Unconventional Alternative Edible Flower Rich in Bioactive Compounds

et al. 2023

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“…and Malic acid It is rich in beta-carotene, glucose, and vitamin C. Phenolic compounds work and facilitate digestion. It also has a great importance that works to continuously form beneficial bacteria in the intestine and inhibit the proliferation of harmful bacteria [5] and [10]. Cucumbers contain glycosides, where glycosides activate enzymes to produce metabolic reactions that interfere with proteins [11] and thus kill harmful microorganisms that cause protein oxidative damage [12].…”

Section: Relative Weight Of Edible Internal Organsmentioning

confidence: 99%

“…The use of broiler meat has flourished at the present time, both internationally and locally, due to the abundance of benefit from it [1] because it contains poultry meat, the high ability to transform the nutritional mass into elements to benefit the body from it and fill the deficiency in the body as a result of the composition of the basic elements [2] Lately, I preferred to use medicinal plants for its many benefits, and it is given to poultry because it is a natural additive instead of adding chemical compounds that are deposited in the body and has many harms to humans, and also because it contains many effective substances, including flavonoids, polyphenols, saponins, glycosides, and others [3] Hibiscus Sabdariffa plants are included in medicinal and food plants that possess a therapeutic property [4], and its leaves are characterized by being rich in active active substances, including 1262 (2023) 072083 IOP Publishing doi:10.1088/1755-1315/1262/7/072083 2 hepsin hydrochloride [5] Red tea has two acids, tartaric acid and citric acid, which improve the absorption of nutrients [6].…”

Section: Introductionmentioning

confidence: 99%

The Effect of Adding Levels Hibisscus sabdariffa.L of Powder in the Ration on the Productive Performance of Broiler Chickens

Faris,

Shanoon,

Aldeen

2023

IOP Conf. Ser.: Earth Environ. Sci.

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The study was carried out in the poultry farms affiliated to Animal Production Research - College of Agriculture - University of Kirkuk. 250 one-day-old, unsexed chickens were used for a period of 45 days, to find out the effect of the local currant powder added to the diet on the productive performance of broiler chickens of the Rose 308 type distributed randomly into 6 treatments divided into 5 replications for each replicate. 10 birds included, the first treatment being control the second contains 0.05 mg of BHT, and the third, fourth, fifth, and sixth contain 0.5, 1, 1.5, and 2% of Hibisscus Sabdariffa.L, respectively. The results showed that there were significant differences at the level of P≤0.05. Forage consumption increased in the sixth treatment for all weeks, and the total rate, except for the sixth week, was superior to T4, T5, and T6. The weight gain recipe outperformed the sixth treatment for all weeks, and in the food conversion treatment T1 decreased in the first week, while in the second week it decreased in T5, while in the third and fifth weeks, and the total rate decreased T6, T5, but in the sixth week it was lower in T6. There were no significant differences in the percentage of purification and in the weights of the carcass, heart and liver, and the gizzard excelled at T6.

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“…The main flavonoids in Rosella are Gossypetin, Hibiscetine, Luteolin, and Quercetin 7-9 . Rosella's flavonoid compounds and phenolic acids provide health benefits, including antiinflammatory, antioxidant, antihypertensive, hypolipidemic, antidiabetic, antimicrobial, and anticarcinogenic [10][11][12] .…”

Section: Introductionmentioning

confidence: 99%

The Protective effect of Hibiscus sabdariffa on Lung Damage in Rats due to Cigarette Smoke Exposure

Fulyani

Yudhistira

Istiadi

et al. 2023

dmj

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Background: Cigarette smoke consists of many free radicals that can reduce antioxidants in the body and further trigger oxidative stress. The state of oxidative stress can be minimized through antioxidant supplementation. Hibiscus sabdariffa (Rosella) is a herbal plant reported to be rich in antioxidants.Objective: To investigate the protective effect of Rosella extract on the microstructure of the lung and plasma Malondialdehyde (MDA) levels of rats exposed to cigarette smoke.Methods: This research is an experimental study with a post-test-only group design. A total of 36 male Sprague Dawley rats were randomly divided into six groups[L1] . Group K was given standard food and free access to water. Group K1, K2, P1, P2, and P3 were exposed to 4 cigarettes/day for 30 consecutive days. Before cigarette smoke exposure, each group received treatment with 1 mL saline (K1), vitamin E 0.2 g/kg b.w. (K2), and infused Rosella 0.25 g/kg b.w. (P1), 0.5 g/kg b.w. (P2), and 1 g/kg b.w. (P3). Plasma MDA levels were measured by the TBARS method. Statistical analysis was performed with one way ANOVA test and continued with a post hoc test.Results: Circulated MDA levels of groups K, K1, K2, P1, P2, and P3 were 1.84 ± 0.18 nmol/mL, 9.57 ± 0.27 nmol/mL, 2.24 ± 0.10 nmol/mL, 4.93 ± 0.31 nmol/mL 3.85 ± 0.55 nmol/mL, and 2.62 ± 0.37 nmol/mL respectively. Cigarette smoke exposure in group K showed significantly higher MDA levels (K versus K1; p < 0.001). The administration of rosella infusion (P1, P2, P3) and or vitamin E supplementation (K2) can significantly suppress the plasma MDA levels due to cigarette smoke exposure ( p < 0.05). The administration of Rosella flower infusion 1 g/kg b.w. has an antioxidant effect similar to vitamin E supplementation 0.2 g/kg b.w. (p = 0.268).Conclusion: The administration of Rosella flower infusion could prevent lung damage from oxidative stress induced by cigarette smoke exposure. Keywords: Cigarette, Hibiscus sabdariffa,MDA, Oxidative stress.

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Physiological Effects and Human Health Benefits of Hibiscus sabdariffa: A Review of Clinical Trials

Cited by 28 publications

References 108 publications

Hibiscus acetosella: An Unconventional Alternative Edible Flower Rich in Bioactive Compounds

Hibiscus acetosella: An Unconventional Alternative Edible Flower Rich in Bioactive Compounds

The Effect of Adding Levels Hibisscus sabdariffa.L of Powder in the Ration on the Productive Performance of Broiler Chickens

The Protective effect of Hibiscus sabdariffa on Lung Damage in Rats due to Cigarette Smoke Exposure

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