Physicochemical Properties of the Turmeric (&lt;i&gt;Curcuma longa&lt;/i&gt; L.) in Jindo Korea

Oh, Dayoung; Kim, Han‐Soo

doi:10.5322/jesi.2019.28.4.403

Cited by 5 publications

(4 citation statements)

References 31 publications

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“…This result is consistent with the findings of Datta et al [36] who reported notably higher levels of K and Ca in branded turmeric powder marketed across India. Similar observations indicating higher contents of K (28.8 g kg −1 ) and Ca (2.3 g kg −1 ) were reported by Oh and Kim [37] for turmeric from Korea. Curry powder is also characterized by high median levels of K (13.4-14.6 g kg −1 ) and Ca (1.47-5.24 g kg −1 ).…”

Section: Contribution To Ais/rdassupporting

confidence: 89%

Estimating the potential of spices for mineral provision in a refugee context in East Africa

et al. 2022

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Micronutrient deficiency remains an enormous problem in refugee settings. Transforming refugees’ food systems through the scaling up of kitchen gardening and fortifying relief food crops with minor food components including nutrient-dense spices can help improve the quality of staple foods. Globally, spices are indispensable in the daily diet and play an important role in the socio-cultural setting of different communities. Forty turmeric and curry powder samples were collected from different market establishments and geographic locations in East Africa. The samples were analyzed for selected elements using Portable X-Ray Fluorescence (PXRF). The contents of potassium (K), calcium (Ca), zinc (Zn) and strontium (Sr) in turmeric powder were statistically different among geographic origins (Ethiopia, Kenya and Uganda). We also aimed to determine if a small portion of spices (turmeric (5 g) and curry (4 g)) would contribute to an adequate intake (AI) or recommended dietary allowance (RDA) for selected minerals, for refugee men and women aged between 19 and 50 years as defined by the Food and Nutrition Board of the Institute of Medicine (IOM). For the reference groups, the contributions of turmeric and curry powder to AI/RDA for K, Ca and Zn varied between 0.48 to 4.13%. On the other hand, turmeric was identified to contribute > 20% AI/RDA for refugee men and women aged between 19 and 50 years for two micro minerals: manganese (Mn) and iron (Fe). Considering turmeric and curry powder of East African origins are good sources of minerals and present acceptable toxic metal(loid)s loads coupled with low cost, these spices particularly turmeric should be more widely popularized and recommended for food-to-spice fortification among the refugee population located in East Africa.

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Section: Contribution To Ais/rdassupporting

confidence: 89%

Estimating the potential of spices for mineral provision in a refugee context in East Africa

et al. 2022

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“…CUR (Figure 1), a molecule with the formula C 21 H 20 O 6 and the structure ((1E,6E)-1,7-bis(4-hydroxy-3methoxyphenyl) hepta-1,6-dien-3,5-dione was initially extracted from turmeric in the year 1815 [37].…”

Section: Chemistry and Pharmacokinetics Of Curcuminmentioning

confidence: 99%

NF-κB pathway as a molecular target for curcumin in diabetes mellitus treatment: Focusing on oxidative stress and inflammation

Zamanian,

Alsaab,

Golmohammadi

et al. 2024

Preprint

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Diabetes mellitus (DM), a chronic metabolic disorder associated with hyperglycemia and other complications, is one of the five priority non communicable diseases of global interest with unprecedented rise in developing countries. Whereas, the current treatment with insulin and oral hypoglycemic agents is aimed at managing the hyperglycemia and associated complications, there is need to explore other critical pathways in the pathogenesis of DM that can act as potential drug targets with better treatment outcomes. This study comprehensively explains the role of cellular and molecular elements, like hyperglycemia-induced oxidative stress, endothelial dysfunction, and Nuclear Factor Kappa B (NF-κB)’s involvement in inflammation and immune regulation, in the onset of DM. With bioactive compounds from natural products gaining popularity as novel drug molecules due to their diverse pharmacological actions, the study also extensively explores the prospective therapeutic benefits of curcumin (CUR), a bioactive compound known for its antioxidant, anti-inflammatory, and hypoglycemic properties, in addressing diabetic complications, predominantly via the modulation of the NF-κB pathway. The findings reveal that CUR administration effectively lowered blood glucose elevation, reinstated diminished serum insulin levels, and enhanced body weight in Streptozotocin -induced diabetic rats. CUR exerts its beneficial effects in management of diabetic complications through regulation of signaling pathways, such as CaMKII, PPAR-γ, NF-κB, and TGF-β1. Moreover, CUR reversed the heightened expression of inflammatory cytokines (TNF-α, IL-1β, IL-6) and chemokines like MCP-1 in diabetic specimens, vindicating its anti-inflammatory potency in counteracting hyperglycemia-induced alterations. CUR diminishes oxidative stress, avert structural kidney damage linked to diabetic nephropathy, and suppress NF-κB activity. Furthermore, CUR exhibited a protective effect against diabetic cardiomyopathy, lung injury, and diabetic gastroparesis. Conclusively, the study posits that CUR could potentially offer therapeutic benefits in relieving diabetic complications through its influence on the NF-κB pathway.

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“…CUR (Figure 1), a molecule with the formula C 21 H 20 O 6 and the structure ((1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl) hepta-1,6dien-3,5-dione was initially extracted from turmeric in 1815. 43 CUR belongs to the diarylheptanoid class of polyphenolic compounds and is characterized by symmetrically substituted aromatic rings with methoxy groups and phenolic OH groups in the ortho position. These rings are linked by a conjugated heptadiene chain that contains an enone segment and a 1,3-diketone structure.…”

Section: Chemistry and Pharmacokinetics Of Curmentioning

confidence: 99%

“…CUR (Figure 1), a molecule with the formula C 21 H 20 O 6 and the structure ((1E,6E)‐1,7‐bis(4‐hydroxy‐3‐methoxyphenyl) hepta‐1,6‐dien‐3,5‐dione was initially extracted from turmeric in 1815 43 …”

Section: Chemistry and Pharmacokinetics Of Curmentioning

confidence: 99%

NF‐κB pathway as a molecular target for curcumin in diabetes mellitus treatment: Focusing on oxidative stress and inflammation

Zamanian,

Alsaab,

Golmohammadi

et al. 2024

Cell Biochemistry & Function

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Diabetes mellitus (DM) is a collection of metabolic disorder that is characterized by chronic hyperglycemia. Recent studies have demonstrated the crucial involvement of oxidative stress (OS) and inflammatory reactions in the development of DM. Curcumin (CUR), a natural compound derived from turmeric, exerts beneficial effects on diabetes mellitus through its interaction with the nuclear factor kappa B (NF‐κB) pathway. Research indicates that CUR targets inflammatory mediators in diabetes, including tumor necrosis factor α (TNF‐α) and interleukin‐6 (IL‐6), by modulating the NF‐κB signaling pathway. By reducing the expression of these inflammatory factors, CUR demonstrates protective effects in DM by improving pancreatic β‐cells function, normalizing inflammatory cytokines, reducing OS and enhancing insulin sensitivity. The findings reveal that CUR administration effectively lowered blood glucose elevation, reinstated diminished serum insulin levels, and enhanced body weight in Streptozotocin ‐induced diabetic rats. CUR exerts its beneficial effects in management of diabetic complications through regulation of signaling pathways, such as calcium–calmodulin (CaM)‐dependent protein kinase II (CaMKII), peroxisome proliferator‐activated receptor gamma (PPAR‐γ), NF‐κB, and transforming growth factor β1 (TGFB1). Moreover, CUR reversed the heightened expression of inflammatory cytokines (TNF‐α, Interleukin‐1 beta (IL‐1β), IL‐6) and chemokines like MCP‐1 in diabetic specimens, vindicating its anti‐inflammatory potency in counteracting hyperglycemia‐induced alterations. CUR diminishes OS, avert structural kidney damage linked to diabetic nephropathy, and suppress NF‐κB activity. Furthermore, CUR exhibited a protective effect against diabetic cardiomyopathy, lung injury, and diabetic gastroparesis. Conclusively, the study posits that CUR could potentially offer therapeutic benefits in relieving diabetic complications through its influence on the NF‐κB pathway.

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Physicochemical Properties of the Turmeric (<i>Curcuma longa</i> L.) in Jindo Korea

Cited by 5 publications

References 31 publications

Estimating the potential of spices for mineral provision in a refugee context in East Africa

Estimating the potential of spices for mineral provision in a refugee context in East Africa

NF-κB pathway as a molecular target for curcumin in diabetes mellitus treatment: Focusing on oxidative stress and inflammation

NF‐κB pathway as a molecular target for curcumin in diabetes mellitus treatment: Focusing on oxidative stress and inflammation

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