Physico-chemical characterization, antioxidant and anticancer activities in vitro of a novel polysaccharide from Melia toosendan Sieb. Et Zucc fruit

He, Li; Ji, Pengfei; Gong, Xingguo; Li, Weiqi; Cheng, Junwen; Hua, Qian; Song, Xiaoling

doi:10.1016/j.ijbiomac.2011.05.028

Cited by 30 publications

(10 citation statements)

References 34 publications

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“…Several natural polysaccharides, which are widely distributed in animals, plants and microorganisms, have been demonstrated to play an important role as free radical scavengers in the prevention of oxidative damage in living organism and can be explored as novel potent antioxidant [5][6][7].…”

Section: Introductionmentioning

confidence: 99%

Antioxidant and hepatoprotective potential of endo-polysaccharides from Hericium erinaceus grown on tofu whey

Zhang

Pan

et al. 2012

International Journal of Biological Macromolecules

101

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Section: Introductionmentioning

confidence: 99%

Antioxidant and hepatoprotective potential of endo-polysaccharides from Hericium erinaceus grown on tofu whey

Zhang

Pan

et al. 2012

International Journal of Biological Macromolecules

101

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“…10A and B, WLP exhibited a reversely limited scavenging activities on hydroxyl radicals compared with ascorbic acid within a concentration range of 2 to 10 mg/mL. At the concentration of 10 mg/mL, the scavenging effects of WLP and ascorbic acid on hydroxyl free radical were 44.23% and 100%, respectively, which was similar to the interpretations of (He et al, 2011;Xu et al, 2012).…”

Section: Hydroxyl Radical Scavenging Activitymentioning

confidence: 51%

Optimization for the Extraction of Polysaccharide from Walnut (Juglans regia L.) Leaves: Antioxidant Activities in Vitro

Yang¹,

Xiao²,

Yu³

et al. 2019

American Journal of Biochemistry and Biotechnology

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Cellulase-assisted extraction of Walnut Leaf Polysaccharide (WLP) was studied. Single factor test and response surface design were employed to optimize the technological conditions. The consequences indicated that the highest WLP yield of 5.21% was achieved with raw material ratio of 50 mL/g, cellulase dose of 41488.52 U/g, enzymolysis pH of 5.88, enzymolysis time of 29.74 min and enzymolysis temperature of 52.07°C. Moreover, in vitro antioxidant assays revealed that WLP has significant eliminating capability against 1, 1-diphenyl-2-picrylhydrazyl (DPPH), 2, 2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) and hydroxyl free radicals in a dose-dependent manner and exhibited a strong reducing power. These results suggest that WLP could be developed as a promising natural antioxidant agent in the pharmaceutical and functional food industries.

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“…Hydroxyl radical is the most reactive radical, which can react with most bio-macromolecules functioning in living cells and induce severe damage to adjacent biomolecules. [ 26 ] The results of hydroxyl radical scavenging activities summarized in Figure 6A showed that hydroxyl radical scavenging activities were improved at increasing concentrations of EPS. At a concentration of 10 mg/mL, EPS exhibited the antioxidant activity of a 100%, which is the same as the scavenging activity of vitamin C. This result indicated that the EPS had a strong hydroxyl radical scavenging activity, which was obviously higher than that of polysaccharides from endophytic Paenibacillus polymyxa EJS-3.…”

Section: Resultsmentioning

confidence: 99%

Preparation and bioactivity of exopolysaccharide from an endophytic fungus Chaetomium sp. of the medicinal plant gynostemma pentaphylla

Zhang¹,

Wang²,

Li³

et al. 2017

Phcog Mag

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Background:Many exopolysaccharides from the endophytes in medicinal plants possess various potential bioactivities.Materials and Methods:The endophytic fungus JY25 was isolated from the leave of the Chinese medicinal plant Gynostemma pentaphylla and identified as Chaetomium sp. by its phylogenetic and physiological analysis. One exopolysaccharide (EPS) fraction was isolated from the fermentation broth by ethanol precipitation and purified by gel filtration chromatography on Sepharose CL-6B. The molecular characteristics were examined by GC-MS, FT-IR, and multiangle laser light scattering (MALLS).Results:The monosaccharide composition analysis indicated that the purified EPS was mainly composed of glucose, mannose, arabinose, and galactose with the molecular ratio of 78.29: 8.99: 8.64: 4.08. FT-IR spectral analysis of the purified EPS revealed prominent characteristic groups, such as carbonyl bond, pyranose ring, and so on. The weight-average molar mass and the polydispersity ratio of the EPS were revealed to be 1.961×104 g/mol and 1.838, respectively. Furthermore, thermo gravimetric analysis (TGA) indicated that the degradation temperature of the purified EPS was 305° C. The purified EPS from the endophytic fungus Chaetomium sp. displayed antioxidant and antiproliferative activities.Conclusion:The results demonstrated that the EPS could be used as a healthful food and material source in pharmaceutical industries.SUMMARY An exopolysaccharides (EPS) with antioxidant and antiproliferative activities from an endophytic fungus Chaetomium sp. was reported. Abbreviations used: ANOVA: Analysis of variance; DPPH: 2,2-diphenyl-1-picrylhydrazyl; EPS: Exopolysaccharide; FT-IR: Fourier transform infrared spectroscopy; GC-MS: Gas chromatography–mass spectrometry; Mw: Mass weight; MALLS: Multiangle laser light scattering; SEC: Size Exclusion Chomatography; SPSS: Statistical Package of the Social Science; TGA: Thermo gravimetric analysis; TFA: Trifluoroacetic acid.

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Physico-chemical characterization, antioxidant and anticancer activities in vitro of a novel polysaccharide from Melia toosendan Sieb. Et Zucc fruit

Cited by 30 publications

References 34 publications

Antioxidant and hepatoprotective potential of endo-polysaccharides from Hericium erinaceus grown on tofu whey

Antioxidant and hepatoprotective potential of endo-polysaccharides from Hericium erinaceus grown on tofu whey

Optimization for the Extraction of Polysaccharide from Walnut (Juglans regia L.) Leaves: Antioxidant Activities in Vitro

Preparation and bioactivity of exopolysaccharide from an endophytic fungus Chaetomium sp. of the medicinal plant gynostemma pentaphylla

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