Physical Exercise in Patients with Severe Kidney Disease

Abstract

Patients with advanced chronic kidney disease (CKD), especially those on long-term dialysis, often suffer from muscle wasting and excessive fatigue. It is known that inactivity, muscle wasting and reduced physical functioning are associated with increased mortality in CKD. Known causes include uraemic myopathy and neuropathy, inactivity, and anaemia. Exercise in patients receiving regular dialysis treatment for end-stage renal disease was first introduced 3 decades ago, but is still only offered in a minority of renal units around the world, despite a significant body of evidence to support its use. Work is needed to increase awareness of the potential benefits of increased physical activity for patients with advanced CKD. This review summarizes the mechanisms of exercise intolerance and debility in advanced CKD patients, the methods used for the estimation of functional capacity, the options currently available for exercise training, and their influence on the well-being of this group of patients.

Effect of intradialytic exercise on fatigue, electrolytes level and blood pressure in hemodialysis patients: A randomized controlled trial

“…Additionally decreased number of patients and drop out of those participating in the exercise program. [16,17] An exercise protocol could lead to improvements in many functions, such as blood pressure, heart function (especially ventricular function in hemodialysis [HD] patients), muscle strength, and respiratory capacity, and reduce muscle atrophy, with excellent results for the QOL. [17] Therefore there is an urgent need to treat fatigue so as to decrease its impact on the life of patient undergoing hemodialysis.…”

Exercise-induced Biochemical Modifications in Muscle in Chronic Kidney Disease: Occult Acidosis as a Potential Factor Limiting the Anabolic Effect of Exercise

“…It is well documented that CKD patients have poor physical functioning (reduced ability to perform everyday activities), low exercise capacity, and significant muscle wasting -a field that has recently been reviewed 1 . These problems arise from a number of factors 1 including inactivity, inflammation, anaemia, reduced muscle function and increased muscle protein catabolism 2 .…”

Treinamento físico melhora a aptidão física e a qualidade de vida de pacientes em hemodiálise

“…Regular practice and adequate prescription of physical exercise are able to relieve this condition 29 . Eight of the 11 patients participating in the training program reported sleep improvement.…”

“…According to Buman and King 30 , chronic pain and disabling conditions, as well as other factors, can lead to sleep impairment. On the other hand, physical exercise has been shown to exert positive effects on sleep quality 29 .…”

“…Regular physical exercise seems to improve the physical fitness and QoL perception of individuals experiencing functional loss 8 . Studies have shown that structured exercise training contributes to the rehabilitation of HD patients, improving the perception of QoL and physical fitness 9,10 . However, these data were obtained in quantitative studies and did not take into consideration the patient's perception.…”