Phthalates in PM2.5 from Shenzhen, China and human exposure assessment factored their bioaccessibility in lung

Lu, Shaoyou; Li, Kang; Liao, Shicheng; Ma, Shengtao; Zhou, Li; Chen, Dingyan; Yu, Yingxin

doi:10.1016/j.chemosphere.2018.03.155

Cited by 41 publications

(6 citation statements)

References 47 publications

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“…, 17 pg m −3 (estimate based on LOQs reported), 25 50–200 pg m −3 , 30 and 96–432 pg m −3 ). 31 The PTV-GC-MS/MS method developed by Sánchez-Piñero et al 34 provided LODs within the range of 2.8–1130 pg m −3 for the target PAEs. Li et al 9 used dual trap GC technique which yielded excellent LODs ranging from 1.1 to 24 pg m −3 for all target PAEs.…”

Section: Resultsmentioning

confidence: 99%

“…Other reports that used GC-SQ/MS for the trace analysis of PAEs and DEHA in PM 2.5 and PM 10 yielded varying ranges of LODs expressed in [mass of analyte] m −3 units (e.g., 17 pg m −3 (estimate based on LOQs reported), 25 50-200 pg m −3 , 30 and 96-432 pg m −3 ). 31 The PTV-GC-MS/MS method developed by Sánchez-Piñero et al 34 provided LODs within the range of 2.8-1130 pg m −3 for the target PAEs. Li et al 9 used dual trap GC technique which yielded excellent LODs ranging from 1.1 to 24 pg m −3 for all target PAEs.…”

Section: Limit Of Detection (Lod) and Limit Of Quantitation (Loq)mentioning

confidence: 99%

“…9,[24][25][26] This technique offers reliable identication of compounds of interest due to extensive electron ionisation mass spectral libraries 27,28 and cost-effectiveness. 29 The technique has been applied for trace-level analysis of PAEs and DEHA in PM using both off-line, 25,30,31 and on-line approaches. 9 Off-line techniques can provide better sensitivity due to the higher organic carbon loading required for the detection of pollutants such as PAEs and DEHA at trace levels.…”

Section: Introductionmentioning

confidence: 99%

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Development and validation of a GC Orbitrap-MS method for the analysis of phthalate esters (PAE) and bis(2-ethylhexyl)adipate (DEHA) in atmospheric particles and its application for screening PM_2.5 from Curitiba, Brazil

Argamino,

Sebben,

da Costa

et al. 2024

Anal. Methods

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Section: Resultsmentioning

confidence: 99%

Section: Limit Of Detection (Lod) and Limit Of Quantitation (Loq)mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Development and validation of a GC Orbitrap-MS method for the analysis of phthalate esters (PAE) and bis(2-ethylhexyl)adipate (DEHA) in atmospheric particles and its application for screening PM_2.5 from Curitiba, Brazil

Argamino,

Sebben,

da Costa

et al. 2024

Anal. Methods

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“…Shenzhen, located in the Pearl River Delta, is one of the most developed and urbanized regions in China. The rapid economic development in Shenzhen in recent decades has led to serious air pollution (Lu et al, 2018). According to the Seventh National Census of China, Shenzhen possesses a young population, with an average age of 33 years.…”

Section: Introductionmentioning

confidence: 99%

Effect of Preconception, Prenatal and Postnatal Exposure to Ambient Air Pollution on Laryngitis in Southern Chinese Children

Liu

Deng

Zhang

et al. 2022

Front. Environ. Sci.

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Environmental exposure is considered to be a main triggering factor of laryngitis, a common upper respiratory tract infection, especially in developing countries. However, unclear detrimental air pollutants and lack of understanding on their early-life exposure and laryngitis warrant further investigation. Therefore, a retrospective cohort including 2328 preschool children was conducted during 2015–2016 in Shenzhen, China. We measured ambient air quality of PM10, SO2 and NO2 in 12 monitoring stations, and obtained childhood laryngitis prevalence and confounding covariates by questionnaire. Multiple logistic regression analysis showed that the lifetime prevalence of childhood laryngitis (12.2%) was associated with an interquartile range increase in late preconception (adjusted odds ratio: 1.43, 95% confidence interval: 1.06‒1.92), prenatal (1.35, 1.02–1.79) and early-postnatal (1.32, 1.11‒1.57) exposure to SO2. Sensitivity analysis revealed that this relationship appeared more obvious among boys without parental atopy, mold/damp stains, or window condensation. Nevertheless, there was no evidence for the association between early-life PM10 and NO2 exposure and childhood laryngitis. These findings suggest that early-life exposure to SO2 significantly increases risk of childhood laryngitis. Preventive measures need to be implemented to mitigate industrial air pollution.

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“…Text S1: Search strategy; Text S2: Estimation of PAEs exposure using time-activity weighted model. References [ 66 , 67 , 68 , 69 , 70 , 71 , 72 , 73 , 74 , 75 , 76 , 77 , 78 , 79 , 80 , 81 , 82 , 83 , 84 ] are cited in the Supplementary Materials.…”

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confidence: 99%

Occurrence and Risk Assessment of Personal PM2.5-Bound Phthalates Exposure for Adults in Hong Kong

Chen

Ward

et al. 2022

IJERPH

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We performed personal PM2.5 monitoring involving 56 adult residents in Hong Kong. Additionally, paired personal and residential indoor fine particle (PM2.5) samples were collected from 26 homes and from 3 fixed monitoring locations (i.e., outdoor samples). Six PM2.5-bound phthalate esters (PAEs)—including dimethyl phthalate (DMP), diethyl phthalate (DEP), di-n-butyl phthalate (DnBP), butyl benzyl phthalate (BBP), di(2-ethylhexyl) phthalate (DEHP), and di-n-octyl phthalate (DnOP)—were measured using a thermal desorption–gas chromatography/mass spectrometer method. Average ∑6PAEs (i.e., summation of six PAE congeners) concentrations in personal PM2.5 exposure (699.4 ng/m3) were comparable with those in residential indoors (646.9 ng/m3), and both were slightly lower than the outdoor levels. DEHP was the most abundant PAE congener (80.3%–85.0%) and found at the highest levels in different exposure categories, followed by BBP, DnBP, and DnOP. Strong correlations were observed between DEHP with DnBP (rs: 0.81–0.90; p < 0.01), BBP (rs: 0.81–0.90; p < 0.01), and DnOP (rs: 0.87–0.93; p < 0.01) in each exposure category. However, no apparent intercorrelations were shown for PAE congeners. Higher indoor concentrations and a stronger correlation between DMP and DEP were found compared with outdoor concentrations. Principal component analysis affirmed heterogeneous distribution and notable variations in PAE sources across different exposure categories. The average daily intakes of ∑6PAEs and DEHP via inhalation were 0.14–0.17 and 0.12–0.16 μg/kg-day for adults in Hong Kong. A time-weighted model was used to estimate PAE exposures incorporating residential indoor and outdoor exposure and time activities. The inhalation cancer risks attributable to measured and estimated personal exposure to DEHP exceeded the U.S. EPA’s benchmark (1 × 10−6). The results provide critical information for mitigation strategies, suggesting that PAEs from both ambient and indoor sources should be considered when exploring the inhalation health risks of PAEs exposure.

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Phthalates in PM2.5 from Shenzhen, China and human exposure assessment factored their bioaccessibility in lung

Cited by 41 publications

References 47 publications

Development and validation of a GC Orbitrap-MS method for the analysis of phthalate esters (PAE) and bis(2-ethylhexyl)adipate (DEHA) in atmospheric particles and its application for screening PM_2.5 from Curitiba, Brazil

Development and validation of a GC Orbitrap-MS method for the analysis of phthalate esters (PAE) and bis(2-ethylhexyl)adipate (DEHA) in atmospheric particles and its application for screening PM_2.5 from Curitiba, Brazil

Effect of Preconception, Prenatal and Postnatal Exposure to Ambient Air Pollution on Laryngitis in Southern Chinese Children

Occurrence and Risk Assessment of Personal PM2.5-Bound Phthalates Exposure for Adults in Hong Kong

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Phthalates in PM2.5 from Shenzhen, China and human exposure assessment factored their bioaccessibility in lung

Cited by 41 publications

References 47 publications

Development and validation of a GC Orbitrap-MS method for the analysis of phthalate esters (PAE) and bis(2-ethylhexyl)adipate (DEHA) in atmospheric particles and its application for screening PM2.5 from Curitiba, Brazil

Development and validation of a GC Orbitrap-MS method for the analysis of phthalate esters (PAE) and bis(2-ethylhexyl)adipate (DEHA) in atmospheric particles and its application for screening PM2.5 from Curitiba, Brazil

Effect of Preconception, Prenatal and Postnatal Exposure to Ambient Air Pollution on Laryngitis in Southern Chinese Children

Occurrence and Risk Assessment of Personal PM2.5-Bound Phthalates Exposure for Adults in Hong Kong

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Resources

About

Development and validation of a GC Orbitrap-MS method for the analysis of phthalate esters (PAE) and bis(2-ethylhexyl)adipate (DEHA) in atmospheric particles and its application for screening PM_2.5 from Curitiba, Brazil

Development and validation of a GC Orbitrap-MS method for the analysis of phthalate esters (PAE) and bis(2-ethylhexyl)adipate (DEHA) in atmospheric particles and its application for screening PM_2.5 from Curitiba, Brazil