“…Therefore, development of new materials and techniques is necessary to obtain more durable implants with lower rejection rates [ 2 , 3 ]. Thus, regenerative medicine continues to search for new scaffolds [ 4 , 5 ], artificial organs [ 6 ], biomaterials [ 7 , 8 , 9 , 10 , 11 , 12 ] and complementary therapies [ 13 , 14 , 15 , 16 , 17 ] in order to optimize tissue regeneration [ 18 ]. Among the experimental repair protocols, the use of long bones can be explained by the ease of access and surgical manipulation, as well as similarity with the clinical application in humans, regarding its remodeling, physiological repair of muscle strength and tension, which can also be analyzed in biomechanical tests [ 9 , 14 , 19 , 20 , 21 ].…”