2021
DOI: 10.3390/pharmaceutics13050724
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Osseointegration Improvement of Co-Cr-Mo Alloy Produced by Additive Manufacturing

Abstract: Cobalt-base alloys (Co-Cr-Mo) are widely employed in dentistry and orthopedic implants due to their biocompatibility, high mechanical strength and wear resistance. The osseointegration of implants can be improved by surface modification techniques. However, complex geometries obtained by additive manufacturing (AM) limits the efficiency of mechanical-based surface modification techniques. Therefore, plasma immersion ion implantation (PIII) is the best alternative, creating nanotopography even in complex struct… Show more

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Cited by 13 publications
(3 citation statements)
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“…e main causes of aseptic loosening are excessive wear and stress shielding of the prosthesis [19]. A large number of studies conducted by domestic and foreign materials and medical science and technology professionals to improve the antiwear and friction-reducing performance of artificial joint materials [20][21][22] show that there is no effective biological testing indicator yet for the phenomenon of osteolysis. For the control of osteolysis phenomenon, firstly, it is necessary to improve the material design and fixation technique of the prosthesis [7].…”
Section: Coated Titanium Alloy Co Cr Mo Alloymentioning
confidence: 99%
“…e main causes of aseptic loosening are excessive wear and stress shielding of the prosthesis [19]. A large number of studies conducted by domestic and foreign materials and medical science and technology professionals to improve the antiwear and friction-reducing performance of artificial joint materials [20][21][22] show that there is no effective biological testing indicator yet for the phenomenon of osteolysis. For the control of osteolysis phenomenon, firstly, it is necessary to improve the material design and fixation technique of the prosthesis [7].…”
Section: Coated Titanium Alloy Co Cr Mo Alloymentioning
confidence: 99%
“…Traditional fixation materials are generally nondegradable, including inert stainless steel (SS), titanium (Ti) and its alloys, and cobalt-chromium (Co-Cr) alloys [ 10 ]. They possess satisfactory biocompatibility, high wear resistance, and adequate mechanical strength ( Table 1 ) [ 11 , 12 , 13 ]. However, they have notable shortcomings when being applied in fracture fixation.…”
Section: Introductionmentioning
confidence: 99%
“…There were no complications that needed to be reported and no diseases or signs recommending the removal of an animal (clinical outcome) were observed 40 . In addition, our research group has experience in the method used, as demonstrated by previously published studies 11,[41][42][43] .…”
mentioning
confidence: 99%