Phomoxanthones A and B, Novel Xanthone Dimers from the Endophytic Fungus <i>Phomopsis</i> Species

Isaka, Masahiko; Jaturapat, Amonlaya; Rukseree, Kamolchanok; Danwisetkanjana, Kannawat; Tanticharoen, Morakot; Thebtaranonth, Yodhathai

doi:10.1021/np010006h

Cited by 205 publications

(170 citation statements)

References 27 publications

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“…In addition, several species of Diaporthe are known from clinical reports of immunocompromised patients, although these pathogens are only provisionally identified to species level (Garcia-Reyne et al 2011;Mattei et al 2013). Diaporthe comprises a major component of endophytes in tropical and temperate trees, and several species have been used in secondary metabolite research (Isaka et al 2001;Li et al 2010a, b;Kaul et al 2012).…”

Section: Recommended Genetic Markersmentioning

confidence: 99%

One stop shop: backbones trees for important phytopathogenic genera: I (2014)

et al. 2014

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Many fungi are pathogenic on plants and cause significant damage in agriculture and forestry. They are also part of the natural ecosystem and may play a role in regulating plant numbers/density. Morphological identification and analysis of plant pathogenic fungi, while important, is often hampered by the scarcity of discriminatory taxonomic characters and the endophytic or inconspicuous nature of these fungi. Molecular (DNA sequence) data for plant pathogenic fungi have emerged as key information for diagnostic and classification studies, although hampered in part by non-standard laboratory practices and analytical methods. To facilitate current and future research, this study provides phylogenetic synopses for 25 groups of plant pathogenic fungi in the Ascomycota, Basidiomycota, Mucormycotina (Fungi), and Oomycota, using recent molecular data, up-to-date names, and the latest taxonomic insights. Lineagespecific laboratory protocols together with advice on their application, as well as general observations, are also provided. We hope to maintain updated backbone trees of these fungal lineages over time and to publish them jointly as new data emerge. Researchers of plant pathogenic fungi not covered by the present study are invited to join this future effort. Bipolaris, Botryosphaeriaceae,

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Section: Recommended Genetic Markersmentioning

confidence: 99%

One stop shop: backbones trees for important phytopathogenic genera: I (2014)

et al. 2014

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“…and periconicins A and B have been isolated from Periconia sp (Isaka et al 2001). The endophytic fungi associated with the medicinal plants not only produce antibacterial molecules but also many other pharmacologically active substances with a potential to act as antitumor agents (Pestalotiopsis microspora, taxol), antifungal agents (Cryptosporiopsis criptocandina, quercine).…”

Section: Introductionmentioning

confidence: 99%

Endophytic fungi found in association with Bacopa monnieri as potential producers of industrial enzymes and antimicrobial bioactive compounds

Katoch¹,

Salgotra²,

Singh³

2014

Braz. arch. biol. technol.

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“…[28] Symmetrical or asymmetrical coupling of identical or slightly different monomeric units is very common and often increases the bioactivity and toxicity. Some examples of these highly toxic mycotoxins include secalonic acids, [29,30] eumetrins, [31,32] xanthonols, [33] rugulotrosins, [34] hirtusneanoside, [35] phomoxanthone, [36,37] and dicerandrols. [38] Herein, we report the discovery of several new aromatic, hydrogenated, and structurally unique ring-extended xanthones from different endophytic fungi.…”

Section: Introductionmentioning

confidence: 99%

Xanthones and Oxepino[2, 3‐b]chromones from Three Endophytic Fungi

Krohn

Kouam

Kuigoua

et al. 2009

Chemistry A European J

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Three new metabolites, microsphaeropsones A-C (1-3) with a unique oxepino[2,3-b]chromen-6-one (ring-enlarged xanthone) skeleton, were isolated from the endophytic fungus Microsphaeropsis species, co-occurring with their putative biogenetic anthraquinoide precursors citreorosein (4) and emodin (5). From another Microsphaeropsis species, large amounts of fusidienol A (8 a), smaller amounts of emodin (5), the known aromatic xanthones 9 a and 9 b, the new 3,4-dihydrofusidienol A (8 b), and the new aromatic xanthone 9 c were isolated. The endophyte Seimatosporium species produced a new aromatic xanthone, seimatoxanthone A (10), and 3,4-dihydroglobosuxanthone A (12), closely related to alpha-diversolonic ester (13) from Microdiplodia sp.. The structures were determined mainly by extensive 1D and 2D NMR experiments and supported by X-ray single-crystal analysis of 1 and the oxidation product 7. The absolute configurations of the microsphaeropsones A-C (1-3) were established by comparison of the electronic and vibrational circular dichroism (ECD and VCD) spectra of 1 with time-dependent DFT (TDDFT) and DFT calculations by using either the solid-state structures or DFT-optimized geometries as inputs. Preliminary studies indicated that 1, 2, and enone 7 showed antibacterial, fungicidal, and algicidal properties.

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Phomoxanthones A and B, Novel Xanthone Dimers from the Endophytic Fungus Phomopsis Species

Cited by 205 publications

References 27 publications

One stop shop: backbones trees for important phytopathogenic genera: I (2014)

One stop shop: backbones trees for important phytopathogenic genera: I (2014)

Endophytic fungi found in association with Bacopa monnieri as potential producers of industrial enzymes and antimicrobial bioactive compounds

Xanthones and Oxepino[2, 3‐b]chromones from Three Endophytic Fungi

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