Abstract:The purpose of the present study was to evaluate the antimicrobial effects of 3-hetarylazoquinoline-2,4diols (19), having substituted or unsubstituted thiazole, benzothiazole, benzimidazole, triazole, isoxazole, and thiadiazole moieties at the 3-position, on bacterial and yeast strains. In addition, compounds and DNA interaction with pUC18 plasmid DNA were studied. The biological effects of these molecules were compared with potential antibiotics ampicillin, chloramfenicol (for bacteria), and ketoconozole (for… Show more
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