Phenolic compound characterisation and antiproliferative activity of “Annurca” apple, a southern Italian cultivar

Mari, Angela; Tedesco, Idolo; Nappo, Annunziata; Russo, Gian Luigi; Malorni, Antonio; Carbone, Virginia

doi:10.1016/j.foodchem.2010.04.023

Cited by 51 publications

(39 citation statements)

References 32 publications

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“…Analyses were run on a Finnigan HPLC system (Thermo Electron Corporation, San Jose, CA) provided with photodiode array detector (DAD). The identity of phenolic acids and flavonoids was confirmed with LC-ESI/ MS/MS experiments and data were compared with those of commercial standards and with those reported in previous works (Mari et al, 2010). The same chromatographic conditions were applied to a HP1100 HPLC system (Agilent, Palo Alto, CA) coupled to a PESciex API-2000 triple-quadrupole mass spectrometer (AB Sciex, Warrington, UK) equipped with a Turbospray (TSI) source.…”

Section: Hplc-dad/esi-ms N Analysismentioning

confidence: 90%

“…HPLC separation and quantification of phenolic compounds in apple peel and flesh extracts and samples obtained from in vitro digestion, transepithelial permeation, and plasma protein binding experiments, were performed according to earlier studies with some modifications (Mari et al, 2010). Identification was possible by comparing spectra and retention times with those of commercial standards and with those reported in previous works (Mari et al, 2010).…”

Section: Hplc-dad/esi-ms N Analysismentioning

confidence: 99%

“…Identification was possible by comparing spectra and retention times with those of commercial standards and with those reported in previous works (Mari et al, 2010). The column selected was a Hypersil BDS C18 column (250 mm Â 4.6 mm, 5 lm) (Thermo, Bellefonte, PA).…”

Section: Hplc-dad/esi-ms N Analysismentioning

confidence: 99%

See 2 more Smart Citations

In vitro bioaccessibility, bioavailability and plasma protein interaction of polyphenols from Annurca apple (M. pumila Miller cv Annurca)

et al. 2013

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Section: Hplc-dad/esi-ms N Analysismentioning

confidence: 90%

Section: Hplc-dad/esi-ms N Analysismentioning

confidence: 99%

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In vitro bioaccessibility, bioavailability and plasma protein interaction of polyphenols from Annurca apple (M. pumila Miller cv Annurca)

et al. 2013

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“…Antiproliferative and pro-apoptotic activities of phenolic enriched peel extracts of different cultivars of apple such as Annurca, Red Delicious and Golden Delicious on HL-60 cell line was also studied. All three extracts were able to decrease cell viability from 50 to 80 %, however, annurca apples peel extract was more efficient to do so (Mari et al 2010). The apple pomace which is generally considered as waste also exhibit good antiproliferative Kahle et al 2005;Lamperi et al 2008;Bhushan et al 2008;Neveu et al 2010 potential and showed IC 50 value of 26.40 mg ml (Savatovic et al 2008).…”

Section: Biological Properties Of Apple Phenolicsmentioning

confidence: 93%

Apple phenolics as nutraceuticals: assessment, analysis and application

Rana

Bhushan

2015

J Food Sci Technol

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Humankind is presently engulfed by convenience quench, modern life style and urbanized diet system leading to progression in array of health disorders. The past decade confronted cardiometabolic disorder (21.8 %), lower respiratory and chronic obstructive lung disease (12.5 %) as the major causes of death world over. In anticipation, scientific communities' have demonstrated the role of healthy diets, especially those rich in fruits and vegetables, for management of such health related issues. These horticultural crops are considered as a good source of polyphenols such as dihydrochalcones, flavanols, flavonols, anthocyanins and phenolic acids. The present article reviews the efforts made to assess the potential of apple phenolic compounds present in fresh fruits, leaves, bark and pomace as dietary polyphenols. Considering the positive impact of such phytochemicals on human health, various nutraceuticals, dietary supplements and phenolic-rich food products are presently available on market shelves. On analytical front, improved instrumentation based on liquid chromatography (HPLC, UPLC, LC/MS/ MS) have made the assessment of phenolics more rapid and reliable. Thus, owing to the emergent interest in natural compounds, it is pertinent to discuss the latest significant research findings on therapeutic aspects along with probable metabolic mechanisms of dietary polyphenols found in apples and their implications on human health.

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“…Quality of apple consists of a combination of visual appearance, flavour and texture. Apple fruit ripening is a process that results in changes in fruit quality such as decreased starch, firmness and fruit removal force, increased red colour and changes in anthocyanin, total phenolic content and total antioxidant activity (MARI et al, 2010).…”

Section: Introductionmentioning

confidence: 99%

Effect of aminoethoxyvinylglycine on biochemical, physicomechanical and colour properties of cv. Braeburn apples

et al. 2013

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The effect of preharvest AVG (aminoethoxyvinylglycine) treatments on the biochemical, physicomechanical properties and colour characteristics of cv. Braeburn apples were determined. AVG was applied in four different doses (0, 100, 300 and 500 mgL -1 AVG) 4 weeks before the estimated harvest date. While the lowest values of total soluble solids content and pH were obtained from 500 mgL -1 AVG treatment, the highest values were obtained from control. The titratable acidity was higher in 500 mgL -1 AVG treatment than those of the 100 and 300 mgL -1 AVG treatments. The highest total phenolic and antioxidant activity of both flesh and skin apple was obtained from control, whereas lowest value was obtained from 500 mgL -1 AVG treatment. With increasing doses of AVG, the total monomeric anthocyanin was reduced. The geometric means, fruit diameter, fruit mass, fruit removal force, flesh and skin firmnesses increased with increasing doses of AVG. The hue angle values of flesh and skin fruit were lower in control. Key words: Malus domestica Borkh, colour, FRAP, phenolic compounds ResumoForam determinados os efeitos do tratamento em pré-colheita com aminoetoxivinilglicina (AVG) nas propriedades bioquímicas, físico-mecânicas e características da cor da maçã 'Braeburn'. AVG foi aplicado quatro semanas antes da data estimada de colheita, em quatro doses (0, 100, 300 e 500 mgL -1 ). Enquanto os menores valores de sólidos solúveis totais e pH foram obtidos no tratamento com 500 mgL -1 AVG, os maiores valores foram obtidos no tratamento com 0 mgL -1 AVG. A acidez titulável foi maior no tratamento com 500 mgL -1 AVG do que nos tratamentos 100 e 300 mgL -1 . A maior atividade de fenólicos totais e antioxidantes na polpa e na casca da maçã foi obtida no tratamento com 0 mgL -1 AVG, enquanto que o menor valor foi obtido no tratamento com 500 mgL -1 AVG. Com o aumento das doses de AVG, a antocianina monomérica total foi reduzida. As médias geométricas diâmetro do fruto, massa do fruto, força de remoção de frutas, polpa e casca aumentaram com o aumento das doses de AVG. Os valores do ângulo da matriz de polpa e casca da fruta foram menores no tratamento com 0 mgL -1 AVG.

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Phenolic compound characterisation and antiproliferative activity of “Annurca” apple, a southern Italian cultivar

Cited by 51 publications

References 32 publications

In vitro bioaccessibility, bioavailability and plasma protein interaction of polyphenols from Annurca apple (M. pumila Miller cv Annurca)

In vitro bioaccessibility, bioavailability and plasma protein interaction of polyphenols from Annurca apple (M. pumila Miller cv Annurca)

Apple phenolics as nutraceuticals: assessment, analysis and application

Effect of aminoethoxyvinylglycine on biochemical, physicomechanical and colour properties of cv. Braeburn apples

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