Phenolic compositions, and antioxidant performance of olive leaf and fruit (Olea europaea L.) extracts and their structure–activity relationships

Xie, Pujun; Huang, Li Xin; Zhang, Caihong; Zhang, Yaolei

doi:10.1016/j.jff.2015.05.005

Cited by 139 publications

(97 citation statements)

References 63 publications

(58 reference statements)

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“…In another study, Xie et al (2015) obtained olive leaf extracts using aqueous ethanol as the solvent with ultrasound and temperature in the extraction process. The TP value obtained by the Folin-Ciocalteu assay of this extract was 24520 mg EAG 100 g -1 .…”

Section: Resultsmentioning

confidence: 99%

“…In both studies, the olive leaf extracts showed lower values of IC 50 , i.e., higher antioxidant activity, than the best OPWE obtained from dry OPW (93.3 μg mL -1 ). The differences in the antioxidant activity by DPPH radical quenching are probably due to the different extraction methods used and the origins in the olive tree (Kiritsakis et al, 2010;Bilgin and Şahin, 2013;Rahmanian et al, 2015;Xie et al, 2015).…”

Section: Resultsmentioning

confidence: 99%

“…The antioxidant effect of the olive leaf extracts may be due to their hydrogen donor ability to form stable free radicals, preventing oxidation and further propagation (Xie et al, 2015). In addition, mixtures of different phenolic compounds in olive leaf extracts have higher antioxidant activity than the individual compounds because of the synergy that occurs between them (Ramos et al, 2013).…”

Section: Resultsmentioning

confidence: 99%

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Effect of the Olive Pruning Wood Extract on Lipid Oxidation in Sunflower Oil.

González

Zúñiga

Olea‐Azar

et al. 2017

Ciencia e investigación agraria

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The production of high quality natural Antioxidants from olive pruning wood extracts and their application to prevent the oxidation of vegetable oils were evaluated. The production of antioxidants from branches of olive pruning wood (OPW) using Soxhlet extraction and ethanol was optimized, evaluating the use of dry and fresh OPW, with extraction of an initial mass of 1 and 3 g and extraction times of 2, 4 and 8 h. For the evaluation of the antioxidant properties of the OPW extracts (OPWEs), the 2.2-diphenyl-1-picrylhydrazyl (DPPH) radical bleaching and ORAC-FL assays were performed. Additionally, the phenolic profile of the OPWEs was obtained by using HPLC-DAD, and the total phenolic composition was quantified by the Folin-Ciocalteu assay. The OPWE obtained from dry OPW using 1 g of initial mass showed the highest content of phenolic compounds and better antioxidant capacity compared to the OPWE obtained from fresh OPW. Both extracts showed the same profiles, but the OPWE obtained from dry OPW showed twice the concentrations of catechin (1.00 g 100 g -1 OPWE) and oleuropein (12.59 g 100 g -1 OPWE). Low concentrations of optimized OPWE showed activity against lipid oxidation of sunflower oil, measured by the peroxide value obtained by microwave and forced air oven heating. Under high temperature conditions and concentrations, the results suggest that OPWE may present the opposite effect.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Effect of the Olive Pruning Wood Extract on Lipid Oxidation in Sunflower Oil.

González

Zúñiga

Olea‐Azar

et al. 2017

Ciencia e investigación agraria

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“…The antioxidant effect of extracts on DPPH free radical scavenging may be due to their hydrogendonating capability, which decreases the stable olive leaf extract DPPH radical to the yellow DPPH-H. Antioxidants can capture the free radical chain of oxidation and form stable free radicals, avoiding further oxidation propagation (Xie et al, 2015). The phenolic compound content was highly correlated with DPPH antioxidant values, but moderate to weak correlation was found between the flavonoid content value and radical scavenging activity (Sifaoui et al, 2014).…”

Section: Dpph Free Radical Scavenging Activity Of Olive Leaf Extractmentioning

confidence: 99%

In vivo correlation of olive leaves extract on some oxidative stress markers in streptozotocin-induced diabetes mellitus in rats

et al. 2018

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SUMMARY:Diabetes mellitus type two (T2DM) is one of the most extensive diseases in the world. Herbal therapy remains a possible adjunct therapy to sustain better glycemic control and reduce complications arising from diabetes. In order to evaluate the curative impacts of olive leaf extract (OLE) on streptozotocin (STZ)-induced diabetic rats, twenty-four Wistar male adult rats were divided into four equal groups; control, diabetic control (45 mg/kg STZ), normal rats treated with OLE (17.8 mg/kg b.wt.), and diabetic rats treated with OLE (45 mg/kg STZ + 17.8 mg/kg b.wt.). The OLE extract was investigated for in vitro antioxidant activity using the DPPH • assay. The phenolic, tannin, and flavonoid contents were determined. The activity of GPX, SOD, and GSH in RBC lysate, CAT in plasma and MDA in serum were measured. The OLE prevented the decrease in GSH and kept MDA around the normal range in the treated diabetic rats. The current study suggests that OLE might be used safely to ameliorate T2DM and its accompanying oxidative stress. KEYWORDS: Antioxidant enzymes activity; Diabetes mellitus type two; Flavonoids; Olive leaves extract; Oxidative stress; PhenolicsRESUMEN: Acción de extractos de hojas de olivo sobre marcadores del estrés oxidativo en diabetes mellitus inducida por estreptozotocina en ratas. La diabetes mellitus tipo dos (DM2) es una de las enfermedades más extensas en el mundo. La terapia con hierbas sigue siendo una terapia complementaria para mantener un mejor control de la glucemia y reducir las complicaciones de la diabetes. Con el fin de evaluar los efectos curativos del extracto de hojas de olivo (OLE) en ratas diabéticas inducidas por estreptozotocina (STZ), veinticuatro ratas Wistar machos adultos se dividieron en cuatro grupos iguales; control, control diabético (45 mg/ kg STZ), ratas normales tratadas con OLE (17.8 mg/kg b.wt) y ratas diabéticas tratadas con OLE (45 mg / kg STZ + 17.8 mg / kg b.wt.). El extracto OLE se investigó para determinar la actividad antioxidante in vitro usando ensayos DPPH • . Se determinaron los fenoles, los taninos y el contenido de flavonoides. Se midió la actividad de GPX, SOD y GSH en lisado de RBC, CAT en plasma y MDA en suero. El OLE evitó la disminución de GSH y mantuvo MDA alrededor del rango normal en las ratas diabéticas tratadas. El estudio actual sugiere que OLE podría utilizarse de forma segura para mejorar la DM2 y el estrés oxidativo que le acompaña. PALABRAS CLAVE: Actividad de enzimas antioxidantes; Diabetes mellitus tipo dos; Estrés oxidativo; Extracto de hojas de olivo; Fenólicos FlavonoidesORCID ID: Afify AMR https://orcid.org/0000-0001-8096-7649, El-Beltagi HS https://orcid.org/0000-0003-4433-2034, Fayed SA https://orcid.org/0000-0002-3449-6679, El-Ansary AE https://orcid.org/0000-0003-0585-1229Citation/Cómo citar este artículo: Afify AMR, El-Beltagi HS, Fayed SA, El-Ansary AE. 2108. In vivo correlation of olive leaves extract on some oxidative stress markers in streptozotocin-induced diabetes mellitus in rats. Grasas Aceites 69 (1), e243. https:/...

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“…Estudos demonstram que a oleuropeina está entre os polifenois mais abundantes em folhas de oliveira, e em muitos casos, é o que se encontra em maior quantidade (BENAVENTE-GARCÍA et al, 2000;BOUAZIZ;SAYADI, 2005;HAYES et al, 2011b;TÓTH et al, 2015;XIE et al, 2015a). A composição de um extrato, incluindo seu conteúdo em compostos fenólicos e flavonoides, varia muito em função de diversos fatores relacionados à planta, como cultivar, localização geográfica e fase de colheita (BILGIN; SAHIN, 2013;BOUAZIZ;SAYADI, 2005;BRAHMI et al, 2013;BRIANTE et al, 2002;GUINDA et al, 2015;KIRITSAKIS et al, 2010;LAGUERRE et al, 2009;MEIRINHOS et al, 2005;RAHMANIAN;JAFARI;WANI, 2015;TALHAOUI et al, 2014).…”

Section: Caracterização Do Extrato De Folhas De Olea Europaea Lunclassified

Atividade antioxidante in vitro de extrato de folhas de oliveira (Olea europaea L.) e seu efeito protetor sobre danos oxidativos em eritrócitos humanos

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.1 ± 1.2 g/mL, respectively. In relation to the antioxidant activity against reactive species of biological importance, the OLE showed high ability to inhibit O 2 • (IC 50 = 52.6 ± 2.1 g/mL) and NO • (IC 50 = 48.4 ± 6.8 g/mL), when compared to ascorbic acid. However, inhibition of HOCl was not as efficient (IC 50 = 714.1 ± 31.4 g/mL). The OLE inhibited induced erythrocyte hemolysis in a concentration dependent manner (IC 50 = 7.8 ± 1.1 g/mL) as well as lipid peroxidation and the formation of methemoglobin, with IC 50 values of 38.0 ± 11.7 and 186.3 ± 29.7 g/mL, respectively. The results suggest that olive leaf extract has effective antioxidant activity in biological systems, based on its scavenging effect of certain reactive species that participate in biochemical processes, and the prevention of oxidative damage in human erythrocytes. So, the intake of olive leaf extract may be related to the prevention of in vivo oxidative stress, with health benefits.

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Phenolic compositions, and antioxidant performance of olive leaf and fruit (Olea europaea L.) extracts and their structure–activity relationships

Cited by 139 publications

References 63 publications

Effect of the Olive Pruning Wood Extract on Lipid Oxidation in Sunflower Oil.

Effect of the Olive Pruning Wood Extract on Lipid Oxidation in Sunflower Oil.

<em>In vivo</em> correlation of olive leaves extract on some oxidative stress markers in streptozotocin-induced diabetes mellitus in rats

Atividade antioxidante <i>in vitro</i> de extrato de folhas de oliveira (<i>Olea europaea</i> L.) e seu efeito protetor sobre danos oxidativos em eritrócitos humanos

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