Phenazinderivat mit starker tuberkulostatischer Wirkung

Vischer, W. A.; Tirunarayanan, M. O.; Bruhin, H.

doi:10.1007/bf02149626

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Guinea-pigs1

Mice1

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1960

1965

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Cited by 4 publications

(2 citation statements)

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“…in the diet fr om the 21st day of infection produced a 50 per cent extension in MST and notably less lung disease in the treated animals. Vischer et al (1958) , Steenken et al (1960) and Drabkina and Ginsberg (1962) also reported unimpressive results in this animal species.…”

Section: Guinea-pigsmentioning

confidence: 76%

See 1 more Smart Citation

The Antimycobacterial Activity of B 663

Barry¹,

Conalty²

1965

Leprosy Review

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B 663 is one of a large series of rimino-compounels of structure 1 synthesizeel originalIy in these laboratories as potential antimycobacterial agents. These are orange-reel phenazine eleriva tives whose colour is relateel to their quinone imine character. In B 663, R" represents 'CH(CHa) 2 anel R' anel R'" are 'C6H4CI(p) resielues. The synthesis anel chemistry of these compounels have been elescribeel by Barry anel co-workers in a series of papers (

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Section: Guinea-pigsmentioning

confidence: 76%

“…other laboratories (Hirsch 1958 ;Vischer et al 1958 ;NoufHard andBerteaux 1955a and1958b ;Acharya et al 1959 ;Grumbach 1960 ;Drabkina and Ginsburg 1962). The drug is also fu lly active against strains resistant to isoniazid, streptomycin.…”

Section: Micementioning

confidence: 98%