Phase plates for wave-aberration compensation in the human eye

Navarro, Rafael; Moreno-Barriuso, Esther; Bará, Salvador; Mancebo, Teresa

doi:10.1364/ol.25.000236

Cited by 110 publications

(55 citation statements)

References 9 publications

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“…After calibration, the system was further tested using a phase plate encoding the aberrations of a real eye [20]. A number of interferograms of the phase plate from a Mach-Zender interferometer (MZI) were recorded for comparison.…”

Section: Resultsmentioning

confidence: 99%

Wavefront curvature sensing for the human eye

Torti

Gruppetta

Diaz-Santana

2008

Journal of Modern Optics

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This is the unspecified version of the paper.This version of the publication may differ from the final published version. In this paper we present a curvature wavefront sensor for the eye. The layout proposed is novel, whilst the algorithm used has been adapted from previously published work [1]. The design of the set-up incorporates two field lenses that, together with a beam separator, define the distance ∆z between the two defocused planes. We present a feasibility study to use this particular combination of optical configuration and retrieval algorithm in the eye. We present calibration curves and results from three real eyes. Permanent

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Section: Resultsmentioning

confidence: 99%

Wavefront curvature sensing for the human eye

Torti

Gruppetta

Diaz-Santana

2008

Journal of Modern Optics

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“…1,2 Reliable measurements of the ocular wave aberration also make it possible to correct these aberrations using advanced methods such as adaptive optics, 3 laser refractive surgery, 4 and customized optics. [5][6][7] Optical and psychophysical tests have demonstrated that correcting these aberrations significantly improves visual performance, especially when the pupil size is relatively large; however, most of these studies have been done in normal eyes. Logically, even greater visual benefit can be achieved when correcting the aberration in eyes having abnormal corneal conditions such as keratoconus ͑cone shape cornea͒.…”

Section: Introductionmentioning

confidence: 99%

Large-dynamic-range Shack-Hartmann wavefront sensor for highly aberrated eyes

2006

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Abstract.A conventional Shack-Hartmann wavefront sensor has a limitation that increasing the dynamic range usually requires sacrificing measurement sensitivity. The prototype large-dynamic-range Shack-Hartmann wavefront sensor presented resolves this problem by using a translatable plate with subapertures placed in conjugate with the lenslet array. Each subaperture is the same size as a lenslet and they are arranged so that they overlap every other lenslet position. Three translations of the plate are required to acquire four images to complete one measurement. This method increases the dynamic range by a factor of two with no subsequent change in measurement sensitivity and sampling resolution of the aberration. The feasibility of the sensor was demonstrated by measuring the higher order aberrations of a custom-made phase plate and human eyes with and without the plate.

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“…The wave-front error of the eye was measured as described previously, 17 and the phase plate was made with a photolithographic process. 15 Measurements of the phase plate show a compensation for 68.5% of the high-order aberrations for the subject. The subject had a total of 1.2-µm rms wave-front error for higher-order aberrations (excluding defocus and astigmatism).…”

mentioning

confidence: 99%

“…Although the phase plate used in this study was specially made, the rapid development of excimer laser systems for customized corneal ablation or lathing systems for customized contact lenses may allow manufacturing of custom phase plates at a relatively low incremental cost. To test the approach we developed a new, medium-magnification confocal imaging system (approximately 3° field of view) that uses a combination of trial lenses for correcting a subject's spherical and cylindrical refractive errors and a custom phase plate 15 to correct higher-order aberrations of the eye statically.…”

mentioning

confidence: 99%

Contrast improvement of confocal retinal imaging by use of phase-correcting plates

et al. 2002

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We have developed a custom scanning laser ophthalmoscope that uses phase plates produced by photolithography to improve the contrast of human retinal images. We combined the scanning engine from a commercial real-time confocal microscope with custom optics to provide medium magnification imaging of the human retina (3° field of view). Defocus and astigmatism were corrected with conventional trial lenses. Higher-order aberrations of the eye were corrected with a phase plate. A 633-nm laser was used for illuminating the retina. Inserting the phase plate into the optical system increased the contrast of a sample retinal vessel by 26%. Additionally, a number of small features of the retina, which were not visible with standard commercial imaging systems, became visible. There results illustrate that, with the rapid development of custom fabrication techniques for refractive corrections, improved diagnostic imaging with little added complexity to existing ophthalmic imaging systems may be realistic.The introduction of adaptive optics into the ophthalmic research community has resulted in a great deal of interest in both correction of aberrations of the eye for improved vision 1-5 and high-resolution imaging of the retina. 1,6 One of the major problems in retinal imaging is that contrasts of most features are low because of both multiple scattering from different layers of the retina and the aberrations of the ocular optics. 7 The scanning laser ophthalmoscope 8 (SLO) has provided a major advantage for retinal imaging because of its ability to improve retinal contrast, especially at longer wavelengths. 9 However, both the spatial resolution and the contrast of confocal SLOs are still limited by the degradation in image quality that is imposed by the optics of the eye.Retinal imaging is commonly used in ophthalmology for the identification and localization of retinal and neural damage. Typically, retinal imaging is performed with fields of view ranging from 10° to 50° of retinal area (approximately 3000-15,000 µ m). We tested whether using customized phase plates allowed higher-contrast imaging of the retina. Although the phase plate used in this study was specially made, the rapid development of excimer laser systems for customized corneal ablation or lathing systems for customized contact lenses may allow manufacturing of custom phase plates at a relatively low incremental cost. To test the approach we developed a new, medium-magnification confocal imaging system (approximately 3° field of view) that uses a combination of trial lenses for correcting a subject's spherical and cylindrical refractive errors and a custom phase plate 15 to correct higher-order aberrations of the eye statically.Our custom SLO is based on a design for dermatological applications 16 (Fig. 1). This SLO uses a polygon to generate the horizontal scan and a galvanometer to generate the vertical scan. 16 We have added a magnification system to increase the pupil size to 5 mm and decrease the field scan to a 3°angle. An optical relay provi...

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Phase plates for wave-aberration compensation in the human eye

Cited by 110 publications

References 9 publications

Wavefront curvature sensing for the human eye

Wavefront curvature sensing for the human eye

Large-dynamic-range Shack-Hartmann wavefront sensor for highly aberrated eyes

Contrast improvement of confocal retinal imaging by use of phase-correcting plates

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