Pharmacological Efficacy of Tamarix aphylla: A Comprehensive Review

Alshehri, Saad Ali; Wahab, Shadma; Abullais, Shahabe Saquib; Das, Gotam; Hani, Umme; Ahmad, Wasim; Amir, Mohd; Ahmad, A.L.; Kandasamy, Geetha; Vasudevan, Rajalakshimi

doi:10.3390/plants11010118

Cited by 25 publications

(23 citation statements)

References 133 publications

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“…Sexual dysfunction is now considered a persistent disorder, particularly among those aged 40 to 70, owing to various physical, psychological, aging, and lifestyle causes [1,2]. People with infertility are more likely to have early ejaculation, reduced sexual desire, and erectile dysfunction [3].…”

Section: Introductionmentioning

confidence: 99%

Ameliorative Sexual Behavior and Phosphodiesterase-5 Inhibitory Effects of Spondias mangifera Fruit Extract in Rodents: In Silico, In Vitro, and In Vivo Study

Khalid

Alqarni

Wahab

et al. 2022

JCM

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The ethanolic extracts of Spondias mangifera fruit (SMFE) were evaluated for aphrodisiac activity. The in-vitro phosphodiesterase-5 (PDE-5) inhibition was assessed based on in-silico molecular docking and simulation studies. In addition, the in-vivo sexual behavior was analyzed in the form of mount (MF, ML), intromission (IF, IL), and ejaculation (EF, EL) frequencies and latencies to validate the in-vitro results. Some biochemical parameters, including PDE-5, nitric oxide, and testosterone, were also observed. The above extract constituted β-amyrin, β-sitosterol, and oleanolic acid and showed tremendous binding with phosphodiesterase-5 and sildenafil. Both the sildenafil and ethanolic extracts (200 and 400 mg/kg/d bodyweight) significantly (p < 0.1, p < 0.05) increased MF, IF, and EF, respectively. In contrast, ML and IL significantly (p < 0.1) decreased, and EL significantly (p < 0.1) increased compared with a normal group of animals. The ethanolic extracts (200 and 400 mg/kg/d bodyweight) and sildenafil further significantly (p < 0.05, p < 0.1) diminished PDE-5 activity significantly (p < 0.05, p < 0.1) and enhanced nitric oxide and testosterone levels, as compared with normal rodents. Therefore, the S. mangifera ethanolic extract might be a valuable alternate aphrodisiac for erectile dysfunction.

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Section: Introductionmentioning

confidence: 99%

Ameliorative Sexual Behavior and Phosphodiesterase-5 Inhibitory Effects of Spondias mangifera Fruit Extract in Rodents: In Silico, In Vitro, and In Vivo Study

Khalid

Alqarni

Wahab

et al. 2022

JCM

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“…Both plant species are well known for their tolerance to salinity. All parts of tamarisk (leaves, florets, and bark) are widely used in the food industry and traditional medicine [ 43 , 76 ]. This species has previously been recorded as a powerful accumulator of selenium, a microelement with high antioxidant properties [ 74 ].…”

Section: Resultsmentioning

confidence: 99%

Evaluation of Factors Affecting Tree and Shrub Bark’s Antioxidant Status

Golubkina

Плотникова

Lapchenko³

et al. 2022

Plants

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The importance of using the barks of trees and shrubs as powerful natural antioxidants suggests the necessity to evaluate the effect of different environmental factors on bark extracts’ quality. The determination of total antioxidant activity (AOA) and polyphenol content (TP) in the bark of 58 tree and shrub species from 7 regions differing in mean annual temperature, insolation, humidity, salinity level, and altitude was performed. The above stress factors positively affected bark AOA but did not have a statistically significant effect on TP. The bark of trees grown in the seashore proximity was characterized by significantly higher AOA than samples gathered in other areas, similarly to the trees grown at high altitude. The bark antioxidant status of 18 species was described for the first time. New sources of powerful antioxidants were represented by the ornamental shrubs Cornus sanguinea and Cornus alba, which showed the highest AOA (169–171 mg GAE g−1 d.w.). Among the typical halophytes, Calligonum and Tamarix had high AOA (172 and 85 mg GAE g−1 d.w.), while in the bark of tamarisk, an Se accumulator, an Se concentration of about 900 µg kg−1 d.w. was recorded. A significant positive correlation was found between leaves and bark AOA in the Karadag Nature Reserve’s deciduous trees (r = 0.898, p < 0.01). The relationship between bark AOA and TP was highly significant (r = 0.809; p < 0.001) for all samples except the mountainous ones. The results of the present research revealed new opportunities in successive bark utilization.

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“…A previous study suggested that Saudi Arabian extracts of the leaves possess valuable content of antioxidants, inflammatory, antibiotic, wound healing, astringent activity, antipyretic, and analgesic agents [ 26 ]. Secondary metabolites found include tannins, flavonoids, alkaloids, isoferulic acid, and ellagic acid, which contributed to the high antifungal rates in this plant [ 27 ].…”

Section: Introductionmentioning

confidence: 99%

The Antifungal Properties of Tamarix aphylla Extract against Some Plant Pathogenic Fungi

Al-Otibi¹,

Moria²,

Alharbi³

et al. 2023

Microorganisms

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Tamarix aphylla is a Saudi herb, which possesses antimicrobial properties and potentially introduces a solution to the subsequent dilemma caused by agrochemicals and antifungal misuse. The current study aimed to assess the fungicidal properties of water and ethanolic extracts of T. aphylla leaves against Macrophomina phaseolina, Curvularia spicifera, and Fusarium spp. The chemical composition of T. aphylla was evaluated by gas chromatography/mass spectrometry technique (GC–MS) and Fourier-transform infrared spectroscopy (FTIR). The antifungal assay assessed the fungal growth inhibition using the poisoned food technique. Scanning and transmission electron microscopy (SEM and TEM) were used to evaluate the structural changes induced in the fungal species post-treatment by T. aphylla. FTIR and GC–MS analysis revealed that T. aphylla extracts were rich in aromatic and volatile compounds, such as Benzeneselenol, Gibberellic acid, and Triaziquone, which proved multiple antifungal properties. The results showed significant inhibition in the growth of all species (p < 0.05) except for F. moniliforme, where the water extract induced the highest mycelial growth inhibition at the dose of 30%. The highest inhibition was for M. phaseolina treated with the water extract (36.25 ± 1.06 mm, p < 0.001) and C. spicifera, treated with the ethanolic extract (27.25 ± 1.77 mm, p < 0.05), as compared to the untreated control and the positive control of Ridomol. SEM and TEM revealed some ultrastructural changes within the fungal growth of treated M. phaseolina, which included the thickening and mild rupture of mycelia. Those findings suggested the robust antifungal properties of T. aphylla against some filamentous fungi. The phenolic composition illustrated the potential fungicidal properties of T. aphylla. Additional studies are required to focus on more antimicrobial properties of T. aphylla against other species, particularly those that might benefit the medical field.

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Pharmacological Efficacy of Tamarix aphylla: A Comprehensive Review

Cited by 25 publications

References 133 publications

Ameliorative Sexual Behavior and Phosphodiesterase-5 Inhibitory Effects of Spondias mangifera Fruit Extract in Rodents: In Silico, In Vitro, and In Vivo Study

Ameliorative Sexual Behavior and Phosphodiesterase-5 Inhibitory Effects of Spondias mangifera Fruit Extract in Rodents: In Silico, In Vitro, and In Vivo Study

Evaluation of Factors Affecting Tree and Shrub Bark’s Antioxidant Status

The Antifungal Properties of Tamarix aphylla Extract against Some Plant Pathogenic Fungi

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