Pharmacokinetics of Contrast Media

Gardeur, D; Lautrou, Jean; Millard, Jean Claude; Berger, Nicole; Metzger, J

doi:10.1097/00004728-198004000-00009

Cited by 37 publications

(4 citation statements)

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“…The concentration of iodine was around 10 À4 mol iodine L À1 , which is a realistic concentration found in urine of patients. 27 The total concentrations of iodine in the three X-ray contrast agents were determined by means of ICP-OES measurements (Table 2). The obtained iodine concentrations were in good agreement with those specified by the manufacturers (Biliscopin: c exp.…”

Section: Resultsmentioning

confidence: 99%

Iodine speciation using thin-layer chromatography coupled to inductively coupled plasma-mass spectrometry by means of an extraction device

Meermann

Möller

Nowak

et al. 2010

J. Anal. At. Spectrom.

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Section: Resultsmentioning

confidence: 99%

Iodine speciation using thin-layer chromatography coupled to inductively coupled plasma-mass spectrometry by means of an extraction device

Meermann

Möller

Nowak

et al. 2010

J. Anal. At. Spectrom.

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“…Their resonant oscillatory behavior is stable, and they remain exclusively within the blood vessels, reflecting the blood volume in a specific field during each enhancement phase [48]. Conversely, a CT-scan iodine-based contrast agent can spread through endothelial cells into interstitial tissue, originating the "interstitial phase" of enhancement; in fact, due to neoplastic neovascularization, the endothelium acquires an increased permeability, determining a faster diffusion in the interstitial district, with a consequent dimming of venous washout during the portal phase [49,50].…”

Section: Discussion and Future Perspectivesmentioning

confidence: 99%

The Role of Contrast-Enhanced Ultrasound (CEUS) in the Detection of Neoplastic Portal Vein Thrombosis in Patients with Hepatocellular Carcinoma

Cerrito,

Ainora,

Di Francesco

et al. 2023

Tomography

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Hepatocellular carcinoma (HCC) is the principal primary liver cancer and one of the most frequent malignant tumors worldwide in patients with chronic liver disease. When diagnosed at an advanced stage, it is often associated with portal vein tumor thrombosis (PVTT), which heavily affects patients’ prognosis. Imaging evaluation is crucial in PVTT detection and staging; computed tomography and magnetic resonance are the principal diagnostic tools. Contrast-enhanced ultrasound (CEUS) is a non-invasive and easily repeatable method that can also be used in patients with impaired renal function. It represents an important means for the identification of PVTT, particularly differentiating neoplastic and non-neoplastic thrombosis through the analysis of ultrasound enhancement characteristics of the thrombosis (arterial hyperenhancement and portal washout), thus allowing more refined disease staging, appropriate treatment planning, and response evaluation, along with prognosis assessment.

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“…The variation in moment and degree of maximum enhancement of the maxillary artery among the dogs in our study may be explained by differences in injection volume, rate of contrast medium injection, body weight, blood viscosity, blood pressure, cardiac output, PCO 2 , and heart rate. [34][35][36][37] To get a better overview of the enhancement pattern of the canine pituitary gland, the maximum enhancement of the maxillary artery was synchronized in all dogs. The shape of the time-density curve of the complete pituitary gland as reported by Love et al 21 is mainly influenced by the early and strong enhancement of the central neurohypophysis and resembles the arterial time-density curves of other organs.…”

Section: Discussionmentioning

confidence: 99%