Pharmacognostic, Antimicrobial and Toxicological Studies of a Seasonal Medicinal Plant; Tagetes Patula L

Abstract

Purpose of this study: This study has been carried out to explore the medicinal significance of Tagetes patula by evaluating its in vitro antibacterial, antifungal and toxicological effects. Pharmacognostic standardization is done to maintain the purity and quality of the drug.
 Methodology: Pharmacognostic studies (macro morphology and microscopy i.e. Histology and powder microscopy), solubility and color reaction of T.patula were carried out followed by in vitro antimicrobial studies of ethanol extract of the flowers. In this regard antibacterial, antifungal, and toxicological studies were performed by well diffusion, Agar dilution, and larvicidal activity respectively.
 Results: Flower extract of T. patula showed good antibacterial effects against gram +ve and gram –ve bacteria except Shigella flexanri. Moreover it showed powerful antifungal effects against various human (Aspergillus flavus, Candida glabrata, Trichophytonlongifusus), plant (Fusariumsolani)and animal pathogens (Microsporumcanis). Moreover remarkable larvicidal activity was observed against brine shrimp at 100 and 1000 µg/ml.
 Conclusion: This research study makes the valuable medicinal plant a good candidate for skin infections and wound management for topical use.Such studies will help in formulating topical herbal preparations to combat inflammatory and infectious skin disease.

Evaluation of Antimicrobial Activity i̇n Extracts of Different Parts of Three Tagetes Species

“…Therefore, they found strong inhibition of both strain by the flower extracts (MIC: 193.3 μg/ml and 253.9 μg/ml, respectively, for M. canis and T. rubrum) and by the arerial parts against T. rubrum (312.5 μg/ml). Recently, Faraz et al (2020) have reported pharmacognostic, antimicrobial and toxicological activities of T. patula L. In that study, ethanol extracted T. patula flowers provided good antimicrobial and larvacidal activities against human pathogens and brine shrimps, respectively.…”

Antibacterial Activity of Marigold Flower (Tagetes Erecta L.) Ethanol Extract Cream Against Staphylococcus Aureus

“…The marigold plant (T. erecta L.) produces flowers and can be used in traditional medicine (Rajkumari et al, 2021;Salehi et al, 2018). This plant has compounds that can be used as cosmetics, overcoming skin irritation and treating itching, packaged in cream preparations obtained from the extraction process (Kumar et al, 2021;Mekjaruskul et al, 2021;Faraz et al, 2020). Marigold flowers have many names depending on where they live (Perez-Ortega et al, 2017;Tyagi et al, 2021).…”