Pharmaceutical and Nutraceutical Potential Applications of Sargassum fulvellum

Abstract

Sargassum fulvellum is a brown seaweed of the Sargassaceae family which has been demonstrated to exhibit antipyretic, analgesic, antiedema, antimicrobial, antioxidant, antitumor, neuroprotective, anticoagulative, anti-inflammatory, and hepatoprotective activities. It has been widely used as a food additive and as a medicine in oriental medicine to treat lumps, dropsy, swelling, testicular pains, and urinary problems. S. fulvellum has been identified as a potential producer of a wide spectrum of natural compounds such as carotenoids, fucoidans, and phlorotannins, showing different biological activities in various industrial applications including pharmaceutical, nutraceutical, cosmeceutical, and functional food. However, the promising health effects associated with the extracts and compounds isolated from S. fulvellum have not been reviewed to date. The present review thus focuses on the biological activity of S. fulvellum as reported by previous publications, which include antioxidant, anticoagulant, anti-inflammatory, neuroprotective, immunomodulatory, antidiabetic, and anticancer effects. Thus, this review might serve to increase the utilization of this invaluable natural source as a potential component in pharmaceutical and nutraceutical applications.

In Vitro and In Vivo Anti-Inflammatory Effects of Sulfated Polysaccharides Isolated from the Edible Brown Seaweed, Sargassum fulvellum

“…S. fulvellum contains various bioactive compounds such as carbohydrates, proteins, pigments, lipids, and phenolic compounds [ 5 , 6 ]. These compounds possess numerous bioactivities such as antioxidant, hepatoprotective, anti-atopic dermatitis, neuroprotective, anti-coagulant, antipyretic, analgesic, and anti-inflammatory effects [ 5 , 7 , 8 , 9 , 10 ]. Kang et al investigated the inhibitory effect of the ethanol extract of S. fulvellum (SFEE) and the compound (grasshopper ketone) isolated from SFEE on atopic dermatitis [ 9 ].…”

The potential Two Types of Green Macroalgae (Caulerpa racemose and Caulerpa lentillifera) as a Natural Food Preservative from Jepara beach, Indonesia

“…However, most of these carbohydratesconsist of gum compounds that are difficult to digest for humans [7]. On the other hand, seaweed is a flora that is required by the food [8], pharmaceutical [9,10], and cosmetic industries [11]. Since ancient times, coastal communities in Jepara and its surroundings have used seaweed as a vegetable.…”

Cytotoxic Sulfoquinovosyl Glycerols from the Seaweed Sargassum Angustifolium from Persian Gulf

“…These compounds are famous because of their especial activities, such as antitumor and anti-inflammatory activities along with improving the intestinal condition. [ 10 11 ] Marine algae synthesize three important types of glycolipids: monogalactosyldiacylglycerides, digalactosyldiacylglycerides, and sulfoquinovosyldiacylglycerides (SQDG). A number of seaweeds can convert simple polyunsaturated fatty acids into complex oxylipins[ 12 ] and these derivatives are extremely useful to keep homeostasis in mammalian systems.…”