Pesquisas em animais: uma reflexão bioética

Franco, Antonio Carlos; Nogueira, Mariana; Sousa, Natália Guimarães Kalatzis; Frota, Matheus Franco da; Fernandes, Clemente Maia da Silva; Serra, Mônica Campos

doi:10.4067/s1726-569x2014000200012

Cited by 13 publications

(11 citation statements)

References 18 publications

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“…Kaidah kesejahteraan hewan saat itu hanya dilakukan untuk mengurangi tingkat stres pada hewan saja dan tidak memperhitungkan penderitaan hewan. Pada tahun 1824, pertama kali dibentuk masyarakat perlindungan hewan, Society for the Preservation of Cruelty to Animals di Inggris untuk mencegah kasus kekejaman pada hewan (Franco et al 2014). Definisi kesejahteraan hewan adalah segala urusan yang berhubungan dengan keadaan fisik dan mental hewan menurut ukuran perilaku alami hewan yang perlu diterapkan dan ditegakkan untuk melindungi hewan dari perlakuan setiap orang yang tidak layak terhadap hewan yang dimanfaatkan manusia (Undang-undang RI Nomor 18 Tahun 2009).…”

Section: Kesejahteraan Hewan (Animal Welfare)unclassified

Animal Welfare Ethics in Research and Testing: Implementation and its Barrier

2020

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Animals have an important role in research and testing to improve human and animal health. Animal usage must be balanced between science and ethical values of animal welfare. This paper discusses the role of IACUC, the implications of animal welfare for research, animal ethical clearance and obstacles in the implementation of animal welfare. Institution of Animal Care Use Committee (IACUC) has an important role to ensure that researcher has animal ethical clearance before conducting research and testing. Research and testing using animal should comply with ethical principles: respect, beneficiary and justice; 3Rs principles: Replacement, Reduction, Refinement and 5F/Freedom: freedom from hunger and thirst, heat and discomfort, pain, trauma and disease, fear and stress and expressing behavior naturally. The application of animal ethics clearance in Indonesia in research using animals is compulsary in various institutions, However thera are several barriers in its implementation, Those are: not all research institutions have IACUC, lack of awareness of researchers to apply for animal ethical clearance, reluctant to IACUC requirements, lack of facilities animals that meet animal welfare requirements and lack of competence in animal handling according to animal welfare.

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Section: Kesejahteraan Hewan (Animal Welfare)unclassified

Animal Welfare Ethics in Research and Testing: Implementation and its Barrier

2020

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“…The advances and contributions obtained by using animals in experiments are widely known. However, bioethical guidelines must be followed to limit the suffering of experimental animals (Lolas, 2008;Franco et al, 2014). Many animal evaluations can be performed using other test systems that provide similar efficiency (Fiskesjö, 1985).…”

Section: Evaluation Of the Effects Of Toxicity And Lethality Of Plantmentioning

confidence: 99%

Efficacy, toxicity, and lethality of plants with potential anthelmintic activity in small ruminants in Brazil

Mottin

Cruz

Neto

et al. 2019

Rev. bras. saúde prod. anim.

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SUMMARY The use of medicinal plants as a therapeutic method in the control of diseases has been increasing in animal production. In the case of small ruminants, the endoparasitic disease is a major concern, since they are considered the greater sanitary problem, especially when considering the phenomenon of parasite resistance to the medicines used. Therefore, the development of alternative methods of endoparasitary control in goats and sheep has become a pressing need. The use of plants to control endoparasites can reduce the use of chemical inputs, making more environmentally sustainable livestock, minimizing the occurrence of parasitic resistance to conventional medicines and contributing to the reduction of production costs. In this sense, several studies have been carried out in order to evaluate the in vitro and in vivo activity of plants with anthelmintic potential. However, despite the potentiality found in many studies, the results are sometimes contradictory or do not replicate in vivo the same efficacy obtained in the in vitro assays. Another relevant aspect is the low utilization of the lethality and toxicity tests, which are indispensable so that the knowledge can be spread and applied by the producers in their herds. Thus, this review aims to provide the results from studies carried out in Brazil with extract of plants with potential for control of parasitic disease in goats and sheep, describing the main evaluated plants species, mechanisms of action, preparation forms and tests of efficacy, toxicity, and lethality.

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“…O papel da Bioética visa viabilizar o diálogo entre os agentes morais e equalizar as decisões baseadas em valores comuns (POTTER, 2016). Franco et al, (2014) frisaram a necessidade de equilíbrio entre as considerações emocionais atreladas ao campo da Ética e as racionais e objetivas, próprias da Ciência. Culminando em soluções responsáveis e viáveis, amparando os humanos, os animais e o ambiente.…”

Section: Introductionunclassified

Limitações no cativeiro quanto a promoção de bem-estar em primatas na percepção do visitante do Zoológico de Curitiba

Artigas

Fischer

2019

Rev. Br. Ed. Amb.

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A continuidade dos zoológicos tem sido condicionada a intervenções conservacionistas e educativas, contudo sua legitimidade é apoiada na demanda da população por entretenimento e contato com a natureza, abstendo-se de uma avaliação crítica a respeito dos limites éticos envolvidos na relação com os animais. Objetivou-se caracterizar o entendimento do visitante quanto ao cativeiro de primatas e analisar a influência do público no comportamento dos animais. Constatou-se que os entrevistados identificaram as limitações do recinto e sugeriram mudanças para elevação do bem-estar animal, contudo, não relacionam sua própria presença como fator de estresse. Os dados suportam a necessidade de ampliação de intervenção da Educação Ambiental aliada a um eficiente processo de comunicação aprimorado por meio da Bioética Ambiental.

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Pesquisas em animais: uma reflexão bioética

Cited by 13 publications

References 18 publications

Animal Welfare Ethics in Research and Testing: Implementation and its Barrier

Animal Welfare Ethics in Research and Testing: Implementation and its Barrier

Efficacy, toxicity, and lethality of plants with potential anthelmintic activity in small ruminants in Brazil

Limitações no cativeiro quanto a promoção de bem-estar em primatas na percepção do visitante do Zoológico de Curitiba

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