Pesquisa do estreptococo do Grupo B em gestantes da Zona Leste de São Paulo

Rev. Inst. Med. trop. S. Paulo

Costa

Silva

et al. 2018

Introduction The aim of this study was to determine the prevalence of GBS colonization in pregnant women in a public health service.Methods A study of 496 pregnant women at 35-37 gestational weeks was conducted from September 2011 to March 2014 in 21 municipalities of the 18th Health Region of Paraná State. Vaginal and anorectal samples of each woman were plated on sheep blood agar, and in HPTH and Todd-Hewitt enrichment broths.Results Of the 496 pregnant women, 141 (28.4%) were positive for GBS based on the combination of the three culture media with vaginal and anorectal samples. The prevalence was 23.7% for vaginal samples and 21.9% for anorectal ones. Among the variables analyzed in this study, only urinary infection was a significant factor (0.026) associated with GBS colonization in women.Conclusions Based on these results, health units should performs universal screening of pregnant women and hospitals should provide adequate prophylaxis, when indicated.

Section: Introductionmentioning

confidence: 99%

Prevalence of Streptococcus agalactiae colonization in pregnant women from the 18th Health Region of Paraná State

Rev. Inst. Med. trop. S. Paulo

Costa

Silva

et al. 2018

“…In Brazil, there are some data on maternal GBS colonization showing different rates 6 - 8 , but there is no official recommendation by the Brazilian Health Ministry regarding the GBS screening in all the pregnant women in order to perform prophylaxis. To achieve the adequate prophylaxis, the knowledge of GBS susceptibility to the primarily used drugs in a given population is needed.…”

Section: Introductionmentioning

confidence: 99%

ANTIMICROBIAL SUSCEPTIBILITY OF Streptococcus agalactiae ISOLATED FROM PREGNANT WOMEN

Rev. Inst. Med. trop. S. Paulo

Santos

Oliveira

et al. 2016

SUMMARYIntroduction:Group B streptococcus (GBS) or Streptococcus agalactiae can colonize the gastrointestinal and genitourinary tracts and has been considered one of the most important risk factors for the development of neonatal disease. The present study evaluated the antimicrobial susceptibility of GBS isolates from pregnant women who were attended at a public health service in Northern Paraná, Brazil. Methods:A descriptive analytical cross-sectional study was performed with 544 pregnant women, at ≥ 35 weeks of gestation. One hundred and thirty-six GBS isolates from pregnant women were tested for antimicrobial susceptibility. Results:All of the GBS isolates showed susceptibility to the drug that is most frequently used for intrapartum prophylaxis: penicillin. Resistance to clindamycin and erythromycin was detected, thus decreasing the options of prophylaxis in women who are allergic to penicillin. Conclusions: Additional studies should be conducted to increase the knowledge of GBS sensitivity profile to antimicrobials in other health centers.

“…The percentage of pregnant women (28.4%), which were GBS carriers at 35–37 weeks of gestation in the present study, corroborates with study conducted by Feuerschuette et al [ 1 ]. Two other studies reported a lower prevalence: 17.4% [ 15 ] and 15.0% [ 16 ]. This variation in GBS maternal detection may be attributable to differences in the applied methodologies to detect GBS and characteristics of the studied populations.…”

Section: Discussionmentioning

confidence: 99%

Performance of Hitchens-Pike-Todd-Hewitt Medium for Group B Streptococcus Screening in Pregnant Women

Gavena

Silva³

et al. 2015

PLoS ONE

Group B streptococcus (GBS), which commonly colonizes the female genital tract and rectum, can cause infections in newborns with varying severity, possibly leading to death. The aim of the present study was to evaluate Hitchens-Pike-Todd-Hewitt (HPTH) medium performance for GBS screening in pregnant women. A descriptive analytical cross-sectional study was performed with 556 pregnant women, of which 496 were at 35-37 weeks of gestation and 60 were at ≥ 38 weeks of gestation. The study was conducted from September 2011 to March 2014 in northern Paraná, Brazil. Vaginal and anorectal clinical specimens from each pregnant woman were plated on sheep blood agar (SBA) and seeded on HPTH medium and Todd-Hewitt enrichment broth. Of the 496 pregnant women at 35-37 weeks of gestation, 141 (28.4%) were positive for GBS, based on the combination of the three culture media and clinical specimens. The GBS colonization rates that were detected by each medium were 22.2% for HPTH medium, 21.2% for SBA, and 13.1% for Todd-Hewitt enrichment broth. Of the 60 pregnant women at ≥ 38 weeks of gestation, seven (11.7%) were positive for GBS. These results demonstrate that HPTH medium and SBA were more sensitive than Todd-Hewitt enrichment broth for GBS screening in pregnant women and good GBS recovery in culture, indicating that the two media should be used together for vaginal and anorectal specimens.