Persistent comorbid symptoms of depression and anxiety predict mortality in heart disease

Doering, Lynn V.; Moser, Debra K.; Riegel, Bárbara; McKinley, Sharon; Davidson, Patricia M.; Baker, Heather; Meischke, Hendrika; Dracup, Kathleen

doi:10.1016/j.ijcard.2009.05.025

Cited by 88 publications

(77 citation statements)

References 54 publications

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“…33 The risk of cardiac mortality among patients with CAD is increased by two to four times for those who have depression. 34 There was a high prevalence of comorbidity with both anxiety and depression, which has also been reported in other studies 8,9,[35][36][37][38] for depressive symptoms. Statistical data suggest that depression and anxiety frequently occur together.…”

Section: Discussionsupporting

confidence: 76%

Screening for symptoms of anxiety and depression in patients admitted to a university hospital with acute coronary syndrome

Meneghetti

Guidolin

Zimmermann

et al. 2017

Trends Psychiatry Psychother.

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Objective: To investigate the prevalence of anxiety and depression in patients admitted for acute coronary syndrome to a university hospital and to examine associations with use of psychotropic drugs. Methods: Ninety-one patients who had had an acute coronary event were enrolled on this cross-sectional prevalence study. Characteristics of the study population and the prevalence rates of depression and anxiety in the sample were assessed using the Hospital São Lucas da Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) psychiatric consultation protocol, which includes clinical and sociodemographic data, and the Hospital Anxiety and Depression Scale (HADS). Results: The prevalence of symptoms of anxiety was 48.4% (44 patients) and the prevalence of depressive symptoms was 26.4% (24 patients). Of these, 19 patients (20.9% of the whole sample) had scores indicative of both types of symptoms concomitantly. Considering the whole sample, just 17 patients (18.7%) were receiving treatment for anxiety or depression with benzodiazepines and/or antidepressants. Conclusions: Anxiety and depression are disorders that are more prevalent among patients with acute coronary syndrome than in the general population, but they are generally under-diagnosed and under-treated. Patients with anxiety and depression simultaneously had higher scores on the HADS for anxiety and depression and therefore require more intensive care.

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Section: Discussionsupporting

confidence: 76%

Screening for symptoms of anxiety and depression in patients admitted to a university hospital with acute coronary syndrome

Meneghetti

Guidolin

Zimmermann

et al. 2017

Trends Psychiatry Psychother.

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“…Although the difference in the correlations may not be clinically significant, it suggests that there was a comorbidity of depression and anxiety in our sample. This may have two not mutually exclusive explanations: a) The comorbidity of depression and anxiety is evident worldwide (Kessler et al, 2015) and in the Arabic population specifically (Al-Turkait et al, 2011;Belzer and Schneier, 2004;Ohaeri et al, 2010) and b) there is evidence that depression is correlated to anxiety in patients with heart disease (Frasure-Smith et al, 1995;Watkins et al, 2013) and this comorbidity can affect between 21% to 26% of the patients (Doering et al, 2010;Frasure-Smith and Lesperance, 2008). Both explanations support the validity of the A-CDS.…”

mentioning

confidence: 97%

Translation and validation of the Cardiac Depression Scale to Arabic

Papasavvas

Al-Amin

Ghabrash

et al. 2016

Asian Journal of Psychiatry

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Background: The Cardiac Depression Scale (CDS) has been designed to measure depressive symptoms in patients with heart disease. There is no Arabic version of the CDS. We translated and validated the CDS in an Arabic sample of patients with heart disease. Methods: Forward and back translation of the CDS was followed by assessment of cultural relevance and content validity. The Arabic version of the CDS (A-CDS) and the Arabic version of the Hospital Anxiety and Depression Scale (A-HADS) were then administered to 260 Arab in-patients with heart disease from 18 Arabic countries. Construct validity was assessed using exploratory factor analysis with polychoric correlations. Internal consistency was assessed using ordinal reliability alpha and item-to-factor polychoric correlations. Concurrent validity was assessed using Pearson's correlation coefficient between the A-CDS and the depression subscale of the A-HADS (A-HADS-D).Results: Cultural relevance and content validity of the A-CDS were satisfactory. Exploratory factor analysis revealed three robust factors, without cross-loadings, that formed a single dimension. Internal consistency was high (ordinal reliability alpha for the total scale and the three factors were .94, .91, .86, and .87, respectively; item-to-factor correlations ranged from .77 to .91). Concurrent validity was high (r = .72). The A-CDS demonstrated a closer to normal distribution of scores than the A-HADS-D. Limitations: Sensitivity and specificity of the A-CDS were not objectively assessed. Conclusions: The A-CDS appears to be a valid and reliable instrument to measure depressive symptoms in a representative sample of Arab in-patients with heart disease.Keywords: Arabic; Cardiac Depression Scale; cultural relevance; depression; heart disease; scale validation Highlights• We translated and validated the Cardiac Depression Scale to Arabic.• Cultural relevance and content validity were satisfactory.• A stable, parsimonious, and meaningful three-factor model was created.• Internal consistency and concurrent validity were high.• The translated scale appears to be a valid and reliable instrument.

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“…Also, in another study, persistence of comorbid depression and anxiety was noted to significantly contribute to mortality (32). In addition, a recent 3-year follow-up study revealed that anxiety and depression were both independently associated with the increased risk of mortality, and cooccurrence of these conditions showed an additive 3-fold increased risk (33).…”

Section: Anxiety In Chd and Long-term Cardiac Outcomesmentioning

confidence: 89%

A Narrative Review of the Relationship Between Coronary Heart Disease and Anxiety

Dahale

Menon

Jaisoorya

2017

Iran J Psychiatry Behav Sci

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Context: Coronary heart disease (CHD) is the most common cause of death and disability in the world. While the relationship between depression and CHD is well documented, anxiety remains understudied, despite its common cooccurrence. Evidence Acquisition: A PubMed (MEDLINE) search was conducted in order to find articles published between January 2000 and December 2015, using the following keywords: "coronary heart disease" and "anxiety". In total, 79 out of 1138 articles were considered relevant by consensus between the authors and were reviewed. Results: According to previous studies, anxiety is suggested to increase the risk of CHD. Anxiety is associated with an increase in cardiac complications, morbidity and mortality. Also, a lower quality of life has been described among patients after acute coronary syndrome, with a few studies reporting contradictory findings. Although studies on anxiety management in CHD are sparse, selective serotonin reuptake inhibitors have been shown to be relatively safe for patients. On the other hand, psychological interventions have not been adequately evaluated, although some studies have revealed their advantages. Conclusions: Evidence suggests that anxiety is associated with the development and course of CHD. Awareness and appropriate training in cardiology settings need to be prioritized to improve early identification and initiation of effective management.

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Persistent comorbid symptoms of depression and anxiety predict mortality in heart disease

Cited by 88 publications

References 54 publications

Screening for symptoms of anxiety and depression in patients admitted to a university hospital with acute coronary syndrome

Screening for symptoms of anxiety and depression in patients admitted to a university hospital with acute coronary syndrome

Translation and validation of the Cardiac Depression Scale to Arabic

A Narrative Review of the Relationship Between Coronary Heart Disease and Anxiety

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