Persistent activity of topical ivermectin against artificial infestations with Hypoderma lineatum (Diptera: Oestridae)

Colwell, Douglas D.; Jacobsen, Johnny A.

doi:10.1016/s0304-4017(02)00011-0

Cited by 13 publications

(4 citation statements)

References 17 publications

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“…Subcutaneous administration of Ivermectin with dose of 0.2mg kg −1 and pour on of that with 0.5mg kg −1 dose, have high effective role for control of parasites, also have important protective role for reinfection in cattle. Also according to findings of researchers, administration of Ivermectin with dose of 0.5mg kg −1 has high effect between 95-100% on Haemonchus, Oesophagostomum and Bunostomum (Egerton et al, 1981;Gary and Kumar, 2007;Reinemeyer and Courtney, 2001) and also on Boophilus, Damalina and others arthropods (Barth and Preston, 1988;Borges et al, 2008;Colwell and Jacobsen, 2002;Lonneux et al, 1997;Marley et al, 1993;Reinemeyer and Courtney, 2001). According to findings of Sharma et al (1990) the efficacy of ivermectin against Ascaridia galli infection was evaluated in chickens under controlled laboratory conditions.…”

Section: Discussionmentioning

confidence: 97%

The Effect of Ivermectin Pour-on Administration Against Natural Heterakis gallinarum Infestation and its Prevalence in Native Poultry

Khayatnouri¹

2011

American Journal of Animal and Veterinary Sciences

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Problem statement: One of the real problems that cause the economic prejudice in animal farms yearly is parasitic diseases. To overcome these problems the use of antiparasitic drugs is necessary. Ivermectin is a broad spectrum antiparasitic agent and different routes of its administration such as injection, oral and pour-on were used. The aims of the current study were evaluation of the efficacy of ivermectin pour-on administration against natural Heterakis gallinarum infection in native poultry and also determination the prevalence rate of this parasite in Tabriz area. Approach:In the present study, 120 native poultry were investigated by Egg Per Gram of feces (EPG) feces test. Willis method was applied for feces test and Mack-master slide method was used for counting nematode eggs. After confirming the infection with worms, Ivermectin (0.5 mg kg⁻¹) pour-on was administrated to infected birds. Fecal examination was repeated in 1, 7, 21 and 28 days post treatment. Results: Results showed that total prevalence of Heterakis gallinarum infection was 21.66% in native poultry of Tabriz area. Efficacy rate of ivermectin pour-on was 59.14, 87.87, 97.65 and 99.57% in 1, 7, 21 and 28 days respectively. Conclusion: In conclusion, the effect of this drug against Heterakis gallinarum resulted in reduction in egg count exceeded 98% (p<0.05), so this drug can be used in antiparasitic program in poultry. Further investigations are necessary to evaluate the drug effect on other nematodes and parasitic infections

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Section: Discussionmentioning

confidence: 97%

The Effect of Ivermectin Pour-on Administration Against Natural Heterakis gallinarum Infestation and its Prevalence in Native Poultry

Khayatnouri¹

2011

American Journal of Animal and Veterinary Sciences

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“…Subcutaneous administration of Ivermectin with dose of 0.2 mg/kg and pour on of that with 0.5 mg/kg dose have high effective role in controlling parasites, and protective role for reinfection in cattle. Also, according to findings of researchers one administration of Ivermectin with dose of 0.5 mg/kg has highly effective between 95 to 100% on Haemonchus, Oesophagostomum and Bunostomum (Egerton et al, 1981;Gary and Kumar, 2007;Reinemeyer and Courtney, 2001); and when Ivermectin with present dose was used, it had effect on Boophilus, Damalina and other arthropods (Borges et al, 2008;Barth and Preston, 1988;Colwell and Jacobsen, 2002;Lonneux et al, 1997;Kassai, 1999;Marley et al, 1993;Reinemeyer and Courtney, 2001). Doramectin (99.2 and 90.7%) were administered (with Ivermectin in one family) after 14 and 21 days, respectively on Cooperia; 99.9 and 93.7% on Ostertagia, after 21 and 28 days, respectively; 100 and 99.9% on Dictyocaulus has important effect.…”

Section: Resultsmentioning

confidence: 94%

The effect of Ivermectin pour-on administration against natural Nematodirus spathiger infestations and prevalent rate of that in cattle

Mirhadi¹,

Garedaghi²,

Saeid³

2011

Afr. J. Microbiol. Res.

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These days one of the real problems that cause the prejudice-economy in animal farms yearly is parasitic disease. For that reason and to prevent these problems the use of antiparasitic drugs is necessary. Ivermectin is a broad spectrum antiparasitic agent and is in different dosage forms such as injection, oral and pour-on. The aims of this study was to evaluate the efficacy of ivermectin pour-on administration against natural Nematodirus spathiger nematode infections in cattle and also to determine the prevalent rate of this parasite in Tabriz area. In this study, 120 heads of male and female hybrid cattle were used for LPG (larves per gram of feces) feces test. Willis method was applied for feces test and Stoll method was used for counting nematode larvae (LPG). After confirming worm contamination and counting N. spathiger nematode larves in feces in infected animals, ivermectin (0.5 mg/kg) pour-on was administrated. Feces test was repeated in 1, 7, 21 and 28 days after treatment. Results showed that total prevalence of N. spathiger nematode infections was 33.33% in cattle of Tabriz area. The effects of ivermectin pour-on on N. spathiger nematode were 13.37, 44.96, 83.69 and 99.1% in 1, 7, 21 and 28 days respectively. In conclusion, because the effect of this drug against N. spathiger nematode was >99% (p<0.05), cattle can use this drug in anti-parasitic programme. Of course, the effect of this drug on other nematodes and parasitic infections need more investigation.

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“…Despite the non-viscous ‘pour-on’ formulations used in animal studies, it is proposed that ivermectin residue may persist on the skin of non-licking cattle for up to 44 days and 23%–50% systemic absorption does occur through dermal absorption 33. Prophylactic administration of 0.003% topical ivermectin was able to prevent fly strike up to 14 weeks in a sheep study34 and successful myiasis treatment was achieved in cattle with ‘micro’ doses (0.002 mg/kg) of ivermectin given subcutaneously 35. These studies suggest that dipteran larvae are sensitive to very low doses of ivermectin and higher doses recommended for the control of a variety of endoparasites and ectoparasites in cattle may not be necessary in myiasis control 36.…”

Section: Discussionmentioning

confidence: 99%

Treatment of nasal myiasis with ivermectin irrigation

Tay¹,

Ramasamy

Watson

et al. 2018

BMJ Case Reports

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We describe a case of nasal myiasis due to in a 97-year-old Peruvian farmer with a previously undiagnosed mucocutaneous leishmaniasis. Initial attempts to remove the fly larvae using manual extraction with a toothed forceps and normal saline irrigation were unsuccessful. On subsequent nasal irrigation with ivermectin solution, the patient self-expulsed approximately 50 larvae within 15 min. He also received a course of oral ivermectin. A post-treatment CT scan revealed clear sinuses. Here, we propose that ivermectin irrigation is a simple and effective treatment for nasal myiasis.

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Persistent activity of topical ivermectin against artificial infestations with Hypoderma lineatum (Diptera: Oestridae)

Cited by 13 publications

References 17 publications

The Effect of Ivermectin Pour-on Administration Against Natural Heterakis gallinarum Infestation and its Prevalence in Native Poultry

The Effect of Ivermectin Pour-on Administration Against Natural Heterakis gallinarum Infestation and its Prevalence in Native Poultry

The effect of Ivermectin pour-on administration against natural Nematodirus spathiger infestations and prevalent rate of that in cattle

Treatment of nasal myiasis with ivermectin irrigation

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