Permanent antimicrobial silicone rubber based on bonding guanidine polymers

Abstract

Recently, silicone rubber (VMQ) was extensively used in household articles and medical devices. To develop a kind of safe and long‐term antimicrobial VMQ was of great significance. In this work, a kind of vinyl‐contained polyhexamethylene guanidine hydrochloride (VPHMG) was synthesized and used as antimicrobial additive for VMQ. With the increasing of VPHMG addition, the mechanical properties and antimicrobial properties of VMQ‐VPHMG were significantly improved. In particular, the antimicrobial rates against Escherichia coli and Staphylococcus aureus were higher than 99.99% as for 4 wt% of VPHMG addition. Moreover, the surface concentration of VPHMG as well as the antimicrobial rates revealed almost unchanged after being extracted by water and methanol. All the results indicated the vinyl‐contained VPHMG vulcanization and therefore provided the permanent antimicrobial performance for VMQ.

Functional modification of silicone rubber through nano‐hydroxylapatite embedding

“…In the biomedical field, a large number of devices namely; catheters, voice prostheses, vascular grafts, and artificial pacemakers are being made from it 3‐6 . However, curing issues (cure inhibition), hydrophobicity, low tensile strength, and poor wear properties, often, affect its performance, utilization, and service life 7‐9 . To alleviate the demerits of SR, many efforts are being undertaken through various methods.…”