Preparation and properties of an antimicrobial acrylic coating modified with guanidinium oligomer

Ding, Xiaoxue; Chen, Fuxiu; Guan, Yong; Zheng, Anna; Wei, Dafu; Xu, Xiang

doi:10.1007/s11998-020-00370-z

Cited by 8 publications

(5 citation statements)

References 24 publications

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“…[31][32][33] Acrylic coating has been extensively applied in building, electronic appliance, and other fields, due to its excellent properties such as aging resistance, transparency, and better decoration. [34] Especially, antimicrobial acrylic coating has broad application prospects in medical equipment, daily necessities, etc. Therefore, N-PMI could also be chosen as antibacterial agent in acrylic coating due to good solubility of organic solvents.…”

Section: Introductionmentioning

confidence: 99%

Antibacterial Mechanism of N‐PMI and the Characteristics of PMMA‐Co‐N‐PMI Copolymer**

Han

Zhuang

Zheng

et al. 2022

Chemistry & Biodiversity

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Aiming at the excellent killing effect of N‐phenylmaleimide (N‐PMI) on microorganisms, this article used structural simulation analysis, fluorescence analysis, confocal laser scanning microscope and SEM to find that the double bond in N‐PMI could interact with the sulfur groups in the membrane protein, changing its conformation, rupturing the plasma membrane of the cell, leaking the contents, and ultimately causing the death of the microorganisms. Therefore, once the double bond participated in the polymerization, N‐PMI lost its antimicrobial function. N‐PMI could achieve azeotropic copolymerization with MMA through reactive extrusion polymerization. N‐PMI with a content of 5 % can be evenly inserted into the PMMA chain segment during the copolymerization reaction, thereby increasing the Tg of pure PMMA by up to 15 °C, which provided the PMMA‐co‐PMI copolymer with resistance to boiling water sterilization advantageous conditions. In addition, N‐PMI with a content of 5 % has little effect on the transparency of PMMA after participating in the copolymerization. Moreover, the trace amount of residual N‐PMI made the material have excellent antimicrobial function, and the bacteriostatic zone is extremely small, which provided an excellent guarantee for the safety and durability of the material. As a medical biological material, the PMMA‐co‐PMI copolymer has a good industrialization application prospects.

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Section: Introductionmentioning

confidence: 99%

Antibacterial Mechanism of N‐PMI and the Characteristics of PMMA‐Co‐N‐PMI Copolymer**

Han

Zhuang

Zheng

et al. 2022

Chemistry & Biodiversity

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“…For example, Zhou et al [18] prepared epoxy acrylic resin by the reaction of diglycidyl ethers of bisphenol-A, PMMA-PnBA-PMMA triblock copolymer and 4,4-methylenebis (3-chloro-2,6-diethyianiline) at 90 O C, and investigated its compatibility and thermal decomposition behavior. Ding et al [19] prepared epoxy acrylic resin by the reaction of glycidyl methacrylate, methyl methacrylate and butyl methacrylate with free radical polymerization mechanism, and then modified the resin with guanidine oligomer for the study of antibacterial coatings. Wang et al [20] prepared epoxy acrylic resin by the copolymerization of E-51, acrylamide, styrene and other monomers through emulsion polymerization and explored its network structure.…”

Section: Introductionmentioning

confidence: 99%

Improving water resistance and mechanical properties of waterborne acrylic resin modified by 3,3′,5,5′-tetramethyl-4,4′-biphenyl diglycidyl ether

Liu

Gao

et al. 2022

Surfaces and Interfaces

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“…Wei et al [ 29 ] demonstrated that aqueous solutions of PHMG with concentrations as low as 1.0 ppm showed more than a 90.0% antibacterial rate. Ding et al [ 30 ] bonded PHMG to resins to generate antibacterial acrylic coatings. The inhibitory factors against both Escherichia coli ( E. coli ) and Staphylococcus aureus ( S. aureus ) were over 99.99% at a PHMG content of 1.0 wt%.…”

Section: Introductionmentioning

confidence: 99%

Preparation and Antifouling Property of Polyurethane Film Modified by PHMG and HA Using Layer-by-Layer Assembly

et al. 2021

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To reduce the possibility of bacterial infection and implant-related complications, surface modification on polyurethane (PU) film is an ideal solution to endow hydrophobic PU with antibacterial and antifouling properties. In this work, a variety of polyhexamethylene guanidine/ hyaluronic acid (PHMG/HA) multilayer films were self-assembled layer-by-layer on PU films using polyanions, carboxyl-activated HA, and polycations PHMG by controlling the concentration of these polyelectrolytes as well as the number of layers self-assembled. Attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR) spectra, water contact angle (WCA), and A Atomic force microscope (AFM) of PU and modified PU films were studied. Protein adsorption and bacterial adhesion as well as the cytotoxicity against L929 of the film on selected PU-(PHMG/HA)5/5-5 were estimated. The results showed that PU-(PHMG/HA)5/5-5 had the best hydrophilicity among all the prepared films, possessing the lowest level of protein adsorption. Meanwhile, this film showed efficient broad-spectrum antibacterial performance as well as significant resistance of bacterial adhesion of more than a 99.9% drop for the selected bacteria. Moreover, almost no influence on cell viability of L929 enhanced the biocompatibility of film. Therefore, the modified PU films with admirable protein absorption resistance, antimicrobial performance, and biocompatibility would have promising applications in biomedical aspect.

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Preparation and properties of an antimicrobial acrylic coating modified with guanidinium oligomer

Cited by 8 publications

References 24 publications

Antibacterial Mechanism of N‐PMI and the Characteristics of PMMA‐Co‐N‐PMI Copolymer**

Antibacterial Mechanism of N‐PMI and the Characteristics of PMMA‐Co‐N‐PMI Copolymer**

Improving water resistance and mechanical properties of waterborne acrylic resin modified by 3,3′,5,5′-tetramethyl-4,4′-biphenyl diglycidyl ether

Preparation and Antifouling Property of Polyurethane Film Modified by PHMG and HA Using Layer-by-Layer Assembly

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