Peritoneal Mesothelioma

Sarcomatoid malignant peritoneal mesothelioma presenting as a localized mesenteric tumor with no previous asbestos exposure

“…Although the main risk factor of malignant peritoneal mesothelioma according to the literature is asbestos exposure, no asbestos exposure is documented in about 20–40% of patients [ 2 , 3 ], and it is the case of our patient who has never been exposed to asbestos.…”

“…According to the literature, there are no specific symptoms and clinical features in malignant peritoneal mesothelioma. Therefore, the preoperative diagnosis is difficult and misdiagnosis can happen [ 3 ]. Indeed, Saisho et al.…”

“…The less common initial complaints including weight loss, abdominal mass, fever, diarrhea, vomiting, and the new-onset hernia can be seen in 32, 30, 22, 17, 15 and 12% patients [ 1 , 4 , 5 ]. Additionally, the clinical presentation with intestinal obstruction, hypercoagulability, thrombocytosis with anemia or surgical emergency (due to acute inflammatory lesions) has been also reported [ 2 , 3 , 7–9 ].…”

“…[ 6 ] reported that laparotomy or laparoscopy with biopsy was required to make the definitive diagnosis in 96% of cases to make a diagnosis of malignant peritoneal mesothelioma. In the Washington Cancer Institute series, diagnosis was obtained by laparotomy in 44% of patients [ 3 ].…”

“…As the second most frequent site after the pleura (65–70%), peritoneal mesothelioma has an incidence of one per million and accounts for 10–30% of all mesotheliomas [ 1 ]. From three basic histologic forms of malignant peritoneal mesothelioma, sarcomatoid mesothelioma is the rarest form [ 2 , 3 ], and the most serious of all asbestos-related diseases [ 4 ]. We present the case of a sarcomatoid malignant peritoneal mesothelioma presenting as a localized mesenteric tumor in a 54-year-old female with no previous asbestos exposure.…”