Excision and primary closure of chronic pilonidal sinus has low recurrence rate with early return to activities. Primary closure appears to be a cost-effective option for uncomplicated pilonidal sinus disease.

With adequate patient selection (guided by histological classification and Ki-67 proliferation index) and complete cytoreduction with HIPEC, satisfactory outcomes can be achieved in selected patients with peritoneal mesothelioma.

Gallbladder function is progressively impaired in Barrett's esophagus and adenocarcinoma. Gallbladder malfunction increases duodenogastric reflux, exposing the lower esophagus to an altered chemical milieu which, in turn, may have a role in promoting metaplasia-dysplasia-neoplasia sequence in the lower esophageal mucosa.

Our study found that the validated 'students' 5Fs' mnemonic retains a role in clinical diagnosis of patients suspected of cholelithiasis but the factor 'familial' should be substituted for 'forty' in recognition of the role of inheritance and the changing demographics of gallstone incidence.

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Collins' sign was positive in over half of all patients with cholelithiasis and was useful discriminator in diagnosis of gallstones.

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