Peripapillary retinal nerve fibre layer thickness in highly myopic Caucasians as measured by Stratus optical coherence tomography

Vernon, S A; Rotchford, Alan P; Negi, Anil; Ryatt, S; Tattersal, C

doi:10.1136/bjo.2007.127571

Cited by 86 publications

(71 citation statements)

References 14 publications

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“…With reference to rim and disc area, our results did not show statistically signi¯cant di®erences in post hoc analysis. These results are in agreement with the results of earlier studies carried out in both adults 26 and children, 8 which revealed signi¯cantly lower values of average peripapillary RNFL thickness in high myopic subjects. In Caucasian children, Barrio-Barrio et al 27 found a signi¯cant association between RNFL (without correction for magni¯ca-tion) and SE and a tendency toward signi¯cance between AL and RNFL.…”

supporting

confidence: 93%

“…However, some previous pediatric studies have shown that RNFL thickness was not associated with age. [25][26][27][28][29][30][31][32][33] It seems that the onset of decrease in the RFNL with age does not appear to be signi¯cant until the age of 15 years. 33 We consider, as Huynh et al 34 suggested, that the growth of macular, RNFL and optic disc parameters is almost complete at birth or soon after it.…”

mentioning

confidence: 99%

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Variations of OCT measurements corrected for the magnification effect according to axial length and refractive error in children

Bueno-Gimeno

España‐Gregori

Gené-Sampedro

et al. 2017

J. Innov. Opt. Health Sci.

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Purpose: The aim of this paper was to examine the distribution of macular, retinal nerve¯ber layer (RNFL) thickness and optic disc parameters of myopic and hyperopic eyes in comparison with emmetropic control eyes and to investigate their variation according to axial length (AL) and spherical equivalent (SE) in healthy children. Methods: This study included 293 pairs of eyes of 293 children (145 boys and 148 girls), ranging in age from 6 to 17 years. Subjects were divided according to SE in control (emmetropia, 99 children), myopia (100 children) and hyperopia (94 children) groups and according to axial AL in 68 short (<22.00 mm, 68), medium (from !22.00 mm to 25.00 mm, 189) and long eyes (>25.00 mm, 36). Macular parameters, RNFL thickness and optic disc morphology were assessed by the Cirrus TM HD-OCT. AL was measured using the IOL-Master system. Littmann's formula was used for calculating the corrected AL-related ocular magni¯cation. Results: Mean age (AE SD) was 10.84 AE 3.05 years; mean (AE SD) SE was þ0.14 AE 0.51 D (range from À8.75 to þ8.25 D) and mean AL (AE SD) was 23.12 AE 1.49. Average RNFL thickness, average macular thickness and macular volume decreased as AL and myopia increased. No correlations between AL/SE and optic disc parameters were found after correcting for magni¯cation e®ect. Conclusions: AL and refractive error a®ect measurements of macular and RNFL thickness in healthy children. To make a correct interpretation of OCT measurements, ocular magni¯cation e®ect should be taken into account by clinicians or OCT manufacturers.

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supporting

confidence: 93%

mentioning

confidence: 99%

Variations of OCT measurements corrected for the magnification effect according to axial length and refractive error in children

Bueno-Gimeno

España‐Gregori

Gené-Sampedro

et al. 2017

J. Innov. Opt. Health Sci.

View full text Add to dashboard Cite

show abstract

“…Myopia is well recognized to be associated with glaucoma; however, it remains uncertain whether RNFL thickness would vary with the refractive status of the eye (4,5). Parameters measured by optical coherence tomography (OCT) in the myopic eye have been previously studied (4)(5)(6)(7)(8).…”

Section: Introductionmentioning

confidence: 99%

“…Parameters measured by optical coherence tomography (OCT) in the myopic eye have been previously studied (4)(5)(6)(7)(8). However, OCT characteristics have not yet been systematically analyzed and compared among different degrees of myopia.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of myopia on retinal nerve fiber layer thickness measured by Spectralis optical coherence tomography

Zha

Zhuang

Lin

et al. 2017

Experimental and Therapeutic Medicine

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Abstract. The aim of the present study was to evaluate the retinal nerve fiber layer (RNFL) thickness of myopic subjects using Spectralis optical coherence tomography (OCT) and to determine variations with age and sex. A total of 271 Chinese participants with a spherical equivalent <+0.50 diopters were enrolled in the research. All subjects underwent a full ophthalmic examination. RNFL thickness was measured and compared according to sex, age and spherical equivalent. No significant difference was demonstrated between RNFL thickness in males and females. No significant difference was observed between RNFL thickness of the two age groups (≤12 years old and >12 years old). Significant differences were observed in all subfields of RNFL thickness among different spherical equivalent groups (P<0.05). In conclusion, myopia did have special influence on RNFL thickness, which was not related to sex or age.

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“…13 Araştırmacılar bu sonucun çalışmalarındaki olgu sayısının azlığı ve yaş aralığının geniş olması ile açıklanabileceğini belirtmişlerdir. 13 Stratus OKT'de RSLT ölçümlerinde refraksiyon kusuru ve aksiyel uzunluğun düzeltmeleri birleştirilmediği için RSLT ölçümleri miyopik olgularda dikkatli yorumlanmalıdır ve henüz normatif veri tabanlarına güvenilmemelidir.…”

Section: Gereç Ve Yöntemlerunclassified

Assessment of Macula and Retinal Nerve Fiber Layer Thickness with Optical Coherence Tomography in Myopia

Özkağnıcı¹,

Tokgöz²

2012

Turkiye Klinikleri J Med Sci

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Ö ÖZ ZE ET T A Am ma aç ç: : Çalışmada emetrop ve miyop olgularda retina yapısının optik koherens tomografi (OKT) ile incelenmesi amaçlandı. G Ge er re eç ç v ve e Y Yö ön nt te em ml le er r: : Çalışma grubu 118'i kadın, 106'sı erkek, toplam 224 olgudan oluşturuldu. Olgular kırma kusuru derecelerine göre birinci grup 0,00/-0,75 D arası (kontrol grubu), ikinci grup -1,00/-3,00 D arası, üçüncü grup -3,25/-6,00 D arası, dördüncü grup ise -6,25/-12,00 D arası olarak dört gruba ayrıldı. Tüm olguların retina sinir lifi tabakası (RSLT) kalınlığı ve makula kalınlığı OKT kullanılarak ölçüldü. B Bu ul lg gu ul la ar r: : Yüksek miyop grupta foveal kalınlık ve volümünde artış tespit edilirken, dış alan dışındaki tüm alanların RSLT kalınlığında azalma bulundu. Ayrıca total makular volüm, dış makular kalınlık ve volümü de azalmıştı. Yüksek miyopik olgularda RSLT'de en fazla incelme %18,6 iç ve %13,1 ile, dış kalınlıkta idi. RSLT kalınlığı, makula kalınlığı ve volüm değerleri ile aksiyel uzunluk/sferik ekivalan arasında zayıf korelasyon mevcuttu. S So on nu uç ç: : Yüksek miyoplarda RSLT'de özellikle iç ve üst kadran incelmesini değerlendirmek çok önemlidir. Foveal çukur ve parafoveolar tepe arasındaki mesafe miyopi ile ters orantılıdır, yani miyopi derecesinde artma makular bölgenin daha düz hâle gelmesine neden olur.A An na ah ht ta ar r K Ke el li im me el le er r: : Miyopi; retina A AB BS ST TR RA AC CT T O Ob bj je ec ct ti iv ve e: : In the study, analysis of retina structure with optical coherence tomography (OCT) in emetropic and myopic cases was aimed. M Ma at te er ri ia al l a an nd d M Me et th ho od ds s: : The study group included a total of 224 cases (118 females, 106 males). Cases were divided into four groups: between 0.00/-0.75 D (first group=control group), between -1.00/-3.00 D (second group), between -3.25/-6.00 D (third group) and between -6.25/-12.00 D, according to their refractive error. Thickness of retinal nerve fiber layer (RNFL) and macula was measured using OCT. R Re es su ul lt ts s: : While an increase was detected in foveal thickness and volume in the highly myopic group, a reduction was found in RNFL thickness of all areas except temporal area. Total macular volume, outer macular thickness and volume were also reduced. The highest thinning of RNFL in highly myopic cases was in 13.1% in superior and 18.6% in nasal thickness. There was a weak correlation between RNFL thickness, macular thickness and volume values and axial length/spheric equivalent. C Co on nc cl lu us si io on n: : Assessment of especially nasal and superior quadrant thickness in RNFL is crucial in highly myopics. Distance between foveal pit and parafoveolar tip is inversely proportional with myopia, in other words, increase in degree of myopia causes macular area to become flatter. Bu çalışmada miyop bireylerin retina dokusunun yapısal ve fonksiyonel özelliklerini belirlemek ve bunların miyopinin derecesi ile ilişkisini incelemek amaçlandı. Bu amaçla optik koherens tomografi (OKT) cihazı ile RSLT ve makula kalınlığı ölçümle...

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Peripapillary retinal nerve fibre layer thickness in highly myopic Caucasians as measured by Stratus optical coherence tomography

Cited by 86 publications

References 14 publications

Variations of OCT measurements corrected for the magnification effect according to axial length and refractive error in children

Variations of OCT measurements corrected for the magnification effect according to axial length and refractive error in children

Evaluation of myopia on retinal nerve fiber layer thickness measured by Spectralis optical coherence tomography

Assessment of Macula and Retinal Nerve Fiber Layer Thickness with Optical Coherence Tomography in Myopia

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