Periorbital edema associated with separate courses of ibuprofen and naproxen

Balas, Morad; Plakogiannis, Roda; Sinnett, Mark J.

doi:10.2146/ajhp090303

Cited by 8 publications

(6 citation statements)

References 18 publications

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“…Hence, the effect of indomethacin on sodium excretion was explained by inhibition of PGs. Similarly, Balas et al reported a case of periorbital edema induced by both ibuprofen and naproxen used on separate occasions (105).…”

Section: Electrolyte and Fluid Retentionmentioning

confidence: 89%

Adverse Effects of Nonsteroidal Antiinflammatory Drugs: An Update of Gastrointestinal, Cardiovascular and Renal Complications

2014

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Non-steroidal anti-inflammatory drugs (NSAIDs) are used chronically to reduce pain and inflammation in patients with arthritic conditions, and also acutely as analgesics by many patients. Both therapeutic and adverse effects of NSAIDs are due to inhibition of cyclooxygenase (COX) enzyme. NSAIDs are classified as non-selective and COX-2-selective inhibitors (COXIBS) based on their extent of selectivity for COX inhibition. However, regardless of their COX selectivity, reports are still appearing on the GI side effect of NSAIDs particularly on the lower gastrointestinal (GI) tract and the harmful role of their controlled release formulations. In addition, previously unpublished data stored in the sponsor's files, question the GI sparing properties of rofecoxib, a COXIB that has been withdrawn due to cardiovascular (CV) side effects. Presently, the major side effects of NSAIDs are the GI complications, renal disturbances and CV events. There is a tendency to believe that all NSAIDs are associated with renal and CV side effects, a belief that is not supported by solid evidence. Indeed, lower but still therapeutics doses of some NSAIDs may be cardioprotective. In this review, we briefly discuss the GI toxicity of the NSAIDs and assess their renal and CV adverse effects in more detail.

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Section: Electrolyte and Fluid Retentionmentioning

confidence: 89%

Adverse Effects of Nonsteroidal Antiinflammatory Drugs: An Update of Gastrointestinal, Cardiovascular and Renal Complications

2014

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“…In this view, all etiological factors should be under account to solve this disturbing symptom by the physicians [7,8]. The some medications associated with periorbital edema such as aspirin, naproxen, ibuprofen, nifedipine, diltiazem, midazolam, topiramate, irbesartan, lamotrigine, niacin, omeprazole, pantoprazole, diltiazem, nifedipine, phenytoin, phenobarbital, hydrochlorothiazide, imanitib and risperidone previously had been reported [10][11][12][13]. In some previous case report, peripheral edema associated with mirtazapine was declared [14,15].…”

Section: Discussionmentioning

confidence: 99%

Mianserin induced periorbital edema: a case report

Gündoğmuş

İspir

Algül

2017

Psychiatry and Clinical Psychopharmacology

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Objectives:The rare side effects as periorbital edema are worth to discuss most of the times. Periorbital edema is a rare and serious allergic condition. The etiology of this situation might be seen in different status that they are commonly independent of each other's as well as their various speculated formation mechanisms. The drug induced side effects might be seen in the etiologic factors basket of periorbital edema. Methods: Observational case report. Results: The authors describe a 30-year-old woman with generalized anxiety disorder who developed periorbital edema while undergoing of treatment with mianserin. Conclusions: Interestingly, we observed a relationship with periorbital edema and a safe, effective, well-tolerated atypical antidepressant-mianserin. This is the first-demonstrated case in literature periorbital edema due to mianserin. The case is enormous importance for contributing the side effect set of periorbital edema. Thus, it will be useful contribution for the daily practice of physicians and the other professions.ARTICLE HISTORY

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“…Several older drugs, such as ibuprofen, naproxen [98], and aspirin [99], have also been implicated in isolated edema of the eyelids. Some antipsychotics such as risperidone [100] and clozapine [101] can also cause eyelid edema, although these reactions are considered rare.…”

Section: Medicationmentioning

confidence: 99%

“…One patient had dependent edema after a craniotomy for a brain tumor. Medications associated with periorbital edema Clozapine [101] Hyaluronidase [97,108] Sulfite [105] Pemetrexed [109] Zoledronic acid [95] Diltiazem [110] Risperidone [100,111] Aspirin [99,112,113] Doxorubicin [107] Imatinib [93,94,[114][115][116] Irbesartan [103] Atracurium [117] Ibuprofen [98,118,119] Epoxy resin [120] Nifedipine [102] Naproxen [98] Lamotrigine [104] Cisplatin [106] Ethosuximide [106] Fluorouracil [106] Hydralazine [106] Metformin [106] Methotrexate [106] Methsuximide [106] Oprelvekin [106] Pioglitazone [106] Rifampicin [106] Rosiglitazone [106] Smallpox vaccine [106] Sulfacetamide [106] Sulfafurazole [106] Sulfamethizole [106] Sulfanilamide [106] Sulfasalazine [106] Sulfathiazole [106] Topiram...…”

Section: Retrospective Case Reviewmentioning

confidence: 99%