Periorbital dermatitis in 4779 patients – patch test results during a 10‐year period

Abstract

Allergic contact dermatitis is a leading cause of periorbital dermatitis. Patch testing should be considered in all patients with periorbital dermatitis when contact allergy is suspected, in order to identify and avoid offending allergens.

Is a specific eyelid patch test series useful? Results of a French prospective study

“…The high proportion of women in our study (90%) is similar to the percentage (70‐90%) reported in previous studies in other countries . It is higher than the 70% proportion of females in French patients patch tested for eczema with various localizations .…”

“…Overall, in 57 (67.9%) of the 84 patients with currently relevant positive test reactions, the dermatitis was attributable to cosmetics. In 11 patients, an eyelid treatment was responsible for the eyelid dermatitis: 8 eye drops, and 3 creams containing budesonide or neomycin . In 3 patients (all men), the eyelid dermatitis was attributable to an occupational allergen.…”

“…Comparison between the different published studies on eyelid dermatitis is difficult, because they have different objectives. Some have focused on the causes of periorbital dermatitis, some on eyelid‐limited contact dermatitis without any other skin involvement, and some on only patients with positive test results or even only on currently relevant test results . One Italian prospective study concerned not only eczema but also other inflammatory dermatitis located on the eyelids, and was mainly a descriptive study .…”

“…Allergic contact dermatitis is the main cause of eyelid dermatitis, and affects 5% to 20% of the patients referred for patch testing . Many studies on eyelid allergic contact dermatitis (EACD) have already been published, but all were retrospective and did not use any targeted allergens, and none included French patients.…”

A case of allergic contact dermatitis caused by Disperse Blue dye in ultrasound gel

“…In 1 large analysis, only 0.6% of >200 000 allergic contact dermatitis cases were caused by an airborne allergen, 35% of which were attributable to occupational exposure . Among almost 5000 periorbital dermatitis cases, only 2.6% were caused by an airborne allergen, and 3.6% were attributable to occupational exposure . One previous report described a case of eyelid allergic contact dermatitis caused by Disperse Blue 106, although ∼5% of patients with eyelid dermatitis react to Disperse Blue 106, one of the most common dye contact allergens tested, in patch testing .…”