A case of allergic contact dermatitis caused by Disperse Blue dye in ultrasound gel

Skalina, Karin; Ramesh, Manish

doi:10.1111/cod.13014

Cited by 4 publications

(2 citation statements)

References 7 publications

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“…Cutaneous adverse events resulting from the use of ultrasound gel are mostly allergic contact dermatitis, but cold urticaria, contact urticaria and anaphylaxis manifestations have been described as well. The allergens reported in allergic contact dermatitis patients include phenoxyethanol, propylene glycol, imidazolidinyl urea, methylisothiazolinone, and, recently, Disperse Blue . Phenoxyethanol has been described as a cause of contact urticaria and anaphylaxis in cosmetics, but we have not found it to be reported as culprit agent in ultrasound gel.…”

Section: Discussionmentioning

confidence: 64%

Contact urticaria caused by phenoxyethanol in ultrasound gel

Aranzabal¹,

Arruti²,

Joral

et al. 2019

Contact Dermatitis

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K E Y W O R D S : CAS no. 122-99-6, case report, contact urticaria, phenoxyethanol, ultrasound gel Phenoxyethanol is a preservative used extensively in cosmetics and pharmaceutical products because of its antibacterial and antifungal properties. Despite its widespread use, it is a rare cause of delayed and immediate contact reactions. We report a case of contact urticaria after use of an ultrasound gel containing phenoxyethanol. CASE REPORTAn 80-year-old woman was referred for evaluation of pruritic, erythematous and oedematous lesions at the site of contact of the ultrasound gel Eco Supergel (Ceracarta Laboratories, Forlì, Italy). The eruption started 10 minutes after contact with the gel at room temperature. The patient had noted previous episodes of swelling and pruritus a few minutes after the application of cosmetics such as moisturizers and wet wipes. An open test on the forearm with Eco Supergel (water, polymer, humectant, preservatives, and colorant) was positive at 10 minutes (Figure 1). As we were not able to obtain the components of the gel, we performed open application tests with some preservatives: at the 10-minute reading, phenoxyethanol (1% pet.) gave a positive result (Figure 2). Open application tests gave negative results with methyldibromo glutaronitrile, propylene glycol, polyethylene glycol, triethanolamine, imidazolidinyl urea, methylisothiazolinone, and Kathon CG (methylchloroisothiazolinone + methylisothiazolinone). The manufacturer confirmed that Eco Supergel contained phenoxyethanol.FIGURE 1 Photograph taken at 30 minutes of the site of application of the ultrasound gel Eco Supergel 132 ARANZABAL ET AL.

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Section: Discussionmentioning

confidence: 64%

Contact urticaria caused by phenoxyethanol in ultrasound gel

Aranzabal¹,

Arruti²,

Joral

et al. 2019

Contact Dermatitis

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“…Ultrasonic or lubricating gels may elicit contact allergy, such as allergic contact dermatitis and more rarely contact urticaria 3 . The main reported allergens reported in ultrasonic or lubricating gels‐induced allergic contact dermatitis are preservatives such as isothiazolinones, formaldehyde releasers, phenoxyethanol, methyldibromoglutaronitrile, parabens and more rarely dyes, carbomers and propylene glycol 4–10 . Of note these gels are considered as medical devices and information about their composition is often poorly detailed or difficult to find which may raise significant issues for patients allergic to one of their constituents.…”

Section: Discussionmentioning

confidence: 99%

A non‐cosmetic allergic contact dermatitis to ethylhexylglycerin

Allichon,

Trebuchon,

Dereure

et al. 2023

Contact Dermatitis

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Highlights in allergic contact dermatitis 2018/2019

Johansen

Werfel

2019

Current Opinion in Allergy &Amp; Clinical Immunology

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Purpose of review The purpose was to highlight recent findings especially concerning new and old allergens, trends, diagnosis and causes of contact allergy. Recent findings Nickel is still the most frequent cause of contact allergy in women and piercings remain an important risk factor. Countries with a long history of regulation of contact allergens have the lowest level of contact allergy to nickel and chromium in Europe. Among the most frequent causes of fragrance contact allergy is terpenes, which are oxidized such as limonene, linalool and in some countries: geraniol. Methylisothiazolinone is still causing considerable problems due to hidden exposures. Acrylates are emerging allergens and 2-hydroxyethyl methacrylate has been included in the 2019 update of the baseline series, as many new cases are seen due to long-lasting nail polish based on acrylates and glue (isobornyl acrylate) in insulin pumps. More than 10 new allergens have been described, which need to be considered in diagnosing contact allergy. Summary Allergic contact dermatitis is a frequent problem, it also constitutes a challenge to diagnose due to many potential contact allergens. The main culprit allergens remain the same, new significant causes are found especially within acrylates.

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A case of allergic contact dermatitis caused by Disperse Blue dye in ultrasound gel

Cited by 4 publications

References 7 publications

Contact urticaria caused by phenoxyethanol in ultrasound gel

Contact urticaria caused by phenoxyethanol in ultrasound gel

A non‐cosmetic allergic contact dermatitis to ethylhexylglycerin

Highlights in allergic contact dermatitis 2018/2019

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