Periodontitis is a factor associated with dyslipidemia

Abstract

Objective To investigate the association between the severity of periodontitis (exposure) and dyslipidemia (outcome). Methods This was a cross‐sectional study of users of public health services. Periodontitis was defined using the Center for Disease Prevention and Control and the American Academy of Periodontology criteria. Lipid evaluation used data on systemic biomarkers. Dyslipidemia diagnosis was based on the Guidelines of total cardiovascular risk of the World Health Organization. Weight, height, waist circumference, and blood pressure were measured, and socioeconomic–demographic, lifestyle behavior factors, general and oral health conditions of the participants were collected. Hierarchical and logistic regression analyzes were used to determine the association between the exposures and the outcome. Odds Ratios, unadjusted and adjusted, and 95% confidence intervals were estimated. Results Of 1,011 individuals examined, 75.17% had dyslipidemia, and 84.17% had periodontitis, 0.2% with mild, 48.56% moderate, and 35.41% severe disease. The association between periodontitis and dyslipidemia was maintained through hierarchical analysis and in the multiple regression modeling, showing that the occurrences of dyslipidemia in the group with periodontitis, and its moderate and severe levels, were, respectively, 14%, 30%, and 16% higher compared with those without periodontitis. Conclusions The results showed a positive association between moderate and severe periodontitis and dyslipidemia.

A Fresh Look at Mouthwashes—What Is Inside and What Is It For?

“…The more refined plant foods do not stimulate saliva flow so efficiently and do not ensure self-cleaning as their unrefined counterparts, which worsen buffering capacity and the remineralisation of enamel and support dental plaque accumulation [ 1 , 2 , 3 , 4 ]. With the development of modern healthcare and access to various foods, periodontal diseases related to vitamin C deficiency are almost forgotten, but the ineffective removal of dental plaque in association with chronic stress, inveterate smoking, diabetes, dyslipidemia, etc., may result in periodontitis, which affects a large part of the population worldwide [ 2 , 5 , 6 , 7 , 8 ]. Rising life expectancy generates other problems such as tissue degeneration as well as neoplasms and their treatment, which may result in hyposalivation, immunodeficiency or malnutrition with subsequent oral diseases [ 9 , 10 , 11 , 12 ].…”

Periodontitis and implant complications in diabetes

“…91,92 In two recent crosssectional studies, the same group of authors found a positive relationship between periodontitis and the triglyceride/high density lipoprotein cholesterol ratio ≥2.3 (odds ratio 1.47) and a positive association between moderate and severe periodontitis and dyslipidemia, specifically 30% and 16% higher, respectively, than in periodontally healthy patients. 93,94 TA B L E 2 Diabetes and periodontitis comorbidities…”

Osteoporosis and Alveolar Bone Health in Periodontitis Niche: A Predisposing Factors-Centered Review

“…Hyperlipidemic individuals manifest advanced periodontal inflammation and tissue destruction compared to normolipidemic subjects [ 185 ]. In the meantime, periodontitis alters the serum lipid profile in a disease severity-dependent manner [ 253 ] and periodontal therapy helps improve the profile of blood lipids [ 254 ]. Nevertheless, these epidemiological studies could not support the cause–effect relationship between hyperlipidemia and periodontitis due to the limitations of cross-sectional studies.…”