Periodontitis and the impact of oral health on the quality of life of psoriatic individuals: a case-control study

Costa, Amanda Almeida; Cota, Luís Otávio Miranda; Mendes, Victor Silva; Oliveira, Alcione Maria Soares Dutra; Cyrino, Renata Magalhães; Costa, Fernando Oliveira

doi:10.1007/s00784-020-03600-1

Cited by 10 publications

(15 citation statements)

References 47 publications

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“…The mechanism by which oral inflammation may be linked to SpA is beyond the scope of the study. However, in light of findings showing involvement of the Th17 pathway in the setting of periodontitis [ 29 , 30 ] and findings from some [ 31 , 32 , 33 ] albeit not all [ 34 ] studies showing that patients with psoriasis or SpA had increased periodontal disease as compared to healthy controls, we suspect that local inflammation may generate an inflammatory response that extends systemically through cross-reactivity or other immunologic mechanisms. A recent review article has likewise reached the conclusion that periodontal inflammation can result in microbiota changes and SpA [ 35 ].…”

Section: Discussionmentioning

confidence: 96%

Pro-Inflammatory Oral Microbiota in Juvenile Spondyloarthritis: A Pilot Study

et al. 2022

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The role of the microbiota in the pathogenesis of arthritis is gaining increasing attention. While multiple studies have queried the intestinal microbiota, very few have analyzed the contents of the oral microbiota. In this pilot study, we obtained salivary and sub-gingival specimens from a cohort of six healthy controls and five children with well-controlled spondyloarthritis (SpA) and performed 16S sequencing on bacteria obtained from both habitats. The Quantitative Insight into Microbial Ecology tool suite was used to generate operational taxonomic units, Phyloseq was used for diversity analyses, and DeSeq2 was used to compare abundances while adjusting for multiple comparisons. A repeat specimen was obtained from one subject during a flare. Clustering based upon diagnosis was observed from both habitats, with decreased alpha diversity seen within the plaque obtained from the patients vs. controls. Among the differentially abundant taxa were statistically significantly increased plaque Fusobacterium and salivary Rothia mucilaginosa among the patients compared to the controls. Additionally, the abundance of plaque Fusobacterium increased in one patient at the time of a flare. Our data suggest that the oral cavity may harbor bacteria involved in the pathogenesis of spondyloarthritis; additional studies are warranted.

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Section: Discussionmentioning

confidence: 96%

Pro-Inflammatory Oral Microbiota in Juvenile Spondyloarthritis: A Pilot Study

et al. 2022

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“…showed in their study 22 . The co‐occurrence of psoriasis and periodontitis affects the quality of life and the negative impact increases with the severity of both diseases 23 . There are minimal data on the association between psoriasis and dental conditions other than periodontitis.…”

Section: Discussionmentioning

confidence: 98%

Oral health status and dental treatment needs of psoriatic patients with different therapy regimes

Olejnik

Adamski

Osmola‐Mańkowska

et al. 2021

Australian Dental Journal

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The aim of the study was to investigate the dental treatment requirements and oral health status of psoriatic patients with different severities of the disease, managed by different methods, including biological therapies. Methods One hundred and twenty‐seven patients diagnosed with psoriasis were enrolled in this study. All subjects completed a general medical history and a Dermatology Life Quality Index (DLQI) questionnaire. The severity of the disease was assessed using the Psoriasis Area and Severity Index (PASI) scale and a DLQI questionnaire. In order to evaluate the oral health status, the following techniques were used: Approximal Plaque Index (API), the Community Periodontal Index (CPI) and the Decayed, Missing and Filled Teeth (DMFT) index. Results Patients treated with biologicals presented a significantly lower mean CPI index and required no surgical interventions. Subjects managed with topical therapy had significantly more decayed teeth and higher treatment needs. Only 11.3% of patients did not require dental intervention. Conclusions The study revealed a high need for dental interventions in patients with psoriasis. The type of treatment used may affect the oral health status of patients. However, further investigations are required to explain the significantly lower CPI value in the group treated with biologicals.

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“…A case–control study conducted by Costa et al [ 41 ] was supposed to indicate the possible impact of periodontitis on the quality of life of patients with psoriasis. In fact, such individuals had a 1.4-times greater chance of periodontal disease, which was also shown in oral-health indexes such as the PCR, BOP, CAL, and PD.…”

Section: Discussionmentioning

confidence: 99%

“… Quality assessment, including the main potential risk of bias (risk level: green—low, yellow—unspecified, red—high; quality score: green—good, yellow—intermediate, red—poor) [ 33 , 34 , 35 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 ]. …”

Section: Figurementioning

confidence: 99%

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Periodontal Disease in Patients with Psoriasis: A Systematic Review

Nijakowski

Gruszczyński

Kolasińska

et al. 2022

IJERPH

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Psoriasis is a chronic, inflammatory, and recurrent skin disease. As with periodontitis, the development and progression of lesions depend on immunological, genetic, and environmental factors. This systematic review was designed to answer the question: “Is there a relationship between psoriasis and periodontal disease?”. Following the inclusion and exclusion criteria, sixteen studies were included in this systematic review (according to PRISMA statement guidelines). Based on the meta-analysis, psoriasis patients showed a more than two-fold increase in the odds of periodontal disease. Almost one-third of these patients suffered from periodontitis of varying severity. Despite the heterogeneity of the included studies, psoriasis is associated with a higher risk of periodontitis, and especially with advanced progression.

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Periodontitis and the impact of oral health on the quality of life of psoriatic individuals: a case-control study

Cited by 10 publications

References 47 publications

Pro-Inflammatory Oral Microbiota in Juvenile Spondyloarthritis: A Pilot Study

Pro-Inflammatory Oral Microbiota in Juvenile Spondyloarthritis: A Pilot Study

Oral health status and dental treatment needs of psoriatic patients with different therapy regimes

Periodontal Disease in Patients with Psoriasis: A Systematic Review

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