Periodontal disease experience in adult long‐duration insulin‐dependent diabetics

Abstract

The aim of this study was to analyse periodontal disease experience in 40- to 70-year-old, sex-matched insulin-dependent diabetics and non-diabetics. The study involved 83 diabetics and 99 non-diabetics. The clinical and radiographic examination comprised recordings of number of teeth, presence of plaque, gingival conditions, probing pocket depth and alveolar bone level (main variable). Diabetics aged 40 to 49 years had more periodontal pockets > or = 6 mm and more extensive alveolar bone loss than non-diabetics in the same age-group. There was also a significantly higher number of subjects belonging to classification groups with severe periodontal disease experience among diabetics in that age-group. In the age-groups 50-59 and 60-69 years, no major differences were found. The disease duration in these 3 age groups was 25.6 years, 20.5 years and 18.6 years, respectively, and the age of onset thus appears to be an important risk factor for future periodontal destruction.

Systemic Diseases Caused by Oral Infection

“…It is well established that diabetics are more likely to develop periodontal disease than nondiabetics (112) and that the disease severity is related to the duration of diabetes (61,138). One plausible biologic mechanism for why diabetics have more severe periodontal disease is that glucose-mediated AGE accumulation affects the migration and phagocytic activity of mononuclear and polymorphonuclear phagocytic cells, resulting in the establishment of a more pathogenic subgingival flora.…”

Expression and Localization of N acetyl glucosamine in diabetic rats

“…Her geçen gün yeni veriler elde edilmekte, diabet ve periodontitis ilişkisi ile ilgili pek çok bilimsel yorum yapılmaktadır. Periodontitisin diabetli bireylerde daha şiddetli ve fazla oranda görülmesindeki mekanizmayı açıklamaya yönelik yapılmış çoğu klinik ve epidemiyolojik çalışma, iddia edilen bazı zıt görüşlere rağmen 17 , diabetli (Tip 1 ve 2) bireylerde diabetli olmayanlara göre daha yüksek oranlarda periodontitis gözlendiğini göstermektedir 18 . Ayrıca, kontrol altında olmayan diabetlilerde kontrol altındakilere göre daha yüksek oranlarda gingivitis ve periodontitis gözlenmektedir 19,20 .…”

Communication and Community

“…Clinical attachment loss is more common in diabetic children and adolescents than in controls (Firatli 1997), and diabetic men have poorer periodontal status than non-diabetic men (Bridges et al 1996). Further, diabetic patients aged 40-49 have more periodontal pockets ≥ 6 mm and more extensive alveolar bone loss than non-diabetic patients in the same age-group (Thorstensson & Hugoson 1993).…”