Perineal squamous cell carcinoma in a goat: a case report

Abstract

SummaryFarjanikish, G., 2017. Perineal squamous cell carcinoma in a goat: A case report. Bulg. J. Vet. Med., 20, No 3,[281][282][283][284][285][286] A 4.5-year old female native Iranian goat was presented with history of an irregularly shaped and cauliflower-like non ulcerated mass that affected the perineum which gradually increased in size. The tumour covered the entire orifice of the anus and extended to the dorsal aspect of the vulva. The mass were excised from the base. On cut-section, reddish white fleshy soft surface with 4×3.5×1 cm dimensions was observed. The enlarging tissue appeared 3 months earlier to presentation as a small neoplastic tissue. The peripheral lymph nodes were normal. There was no evidence of another cutaneous lesion or of metastasis to other organs. Histopathological examination revealed a welldifferentiated squamous cell carcinoma displaying central pearls of keratin and a dense fibrous stroma. The tumour cell was large and had an abundant eosinophilic cytoplasm with slightly enlarged hyperchromatic nuclei. They will often produce large amounts of keratin, resulting in the formation of extracellular keratin pearls. Tumour cells showed hyperchromatism and mitotic figure in some areas. Based on histopathological characteristics the tumour was diagnosed as squamous cell carcinoma.