Percutaneous Vertebral Augmentation for Osteoporotic Vertebral Compression Fractures Will Increase the Number of Subsequent Fractures at Adjacent Vertebral Levels: A Systematic Review and Meta-analysis

Sun, Haibo; Shan, Jianlin; Tang, Hai

doi:10.37766/inplasy2021.5.0097

Cited by 9 publications

(11 citation statements)

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“…DPQ included four aspects of daily activity (da), work and entertainment (wl), anxiety and depression (ad), and social interest (SI). A higher score indicated more severe pain ( 12 ).…”

Section: Methodsmentioning

confidence: 99%

“…DPQ included four aspects of daily activity (da), work and entertainment (wl), anxiety and depression (ad), and social interest (SI). A higher score indicated more severe pain (12). ( 4) The MOS short-term (SF-36) scores of the health survey before treatment, 3 days after treatment, 3 months after treatment, and 6 months after treatment were compared between the two groups.…”

Section: Data Collection and Clinical Evaluationmentioning

confidence: 99%

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Treatment of Elderly Patients with Acute Symptomatic OVCF: A Study of Comparison of Conservative Treatment and Percutaneous Kyphoplasty

et al. 2022

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ObjectiveThe present study was designed for the contrastive analysis of conservative and percutaneous kyphoplasty (PKP) on pain severity and recovery of injured vertebrae in elderly patients with acute symptomatic osteoporotic vertebral compression fracture (OVCF).MethodsA total of 60 elderly patients with acute symptomatic OVCF were divided into two groups according to different treatment protocols, with 30 patients in each group. Patients in the Con group received conservative treatment, while patients in the PKP group received percutaneous kyphoplasty treatment. Clinical evaluation included the visual analogue scale (VAS), the Dallas pain questionnaire, the vertebral body leading edge height, the Cobb angle of injured vertebrae, the MOS item short-form health survey (SF-36), the Barthel index, and the mini-mental state examination (MMSE).ResultsAt 3 days, 3 months, and 6 months post-treatment, the score of VAS and the Cobb angle of injured vertebrae in patients of the PKP group were all significantly lower than those in the Con group (P < 0.05), while the height of vertebral body leading edge in patients of the PKP group was significantly longer than that in the Con group (P < 0.05). At 6 months post-treatment, the scores of the four dimensions of the Dallas pain questionnaire scale in the PKP group were all significantly lower than those in the Con group (P < 0.05), while the score of SF-36 (PCS), SF-36 (MCS), and Barthel index in patients of the PKP group were all significantly lower than those in the Con group (P < 0.05), and there was no significant difference in the scores of MMSE between these two groups (P > 0.05).ConclusionCompared with conservative treatment, PKP treatment of elderly patients with acute symptomatic OVCF provides rapid pain relief, restoration of damaged vertebral body height, correction of Cobb's angle, and improved quality of life.

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“…DPQ included four aspects of daily activity (da), work and entertainment (wl), anxiety and depression (ad), and social interest (SI). A higher score indicated more severe pain ( 12 ).…”

Section: Methodsmentioning

confidence: 99%

Section: Data Collection and Clinical Evaluationmentioning

confidence: 99%

Treatment of Elderly Patients with Acute Symptomatic OVCF: A Study of Comparison of Conservative Treatment and Percutaneous Kyphoplasty

et al. 2022

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“…However, the frequency of vertebral refracture after PVP is equal to that without PVP. Vertebral refractures after PVP can also occur in adjacent as well as distant vertebral bodies [ 3 , 24 , 48 , 49 , 69 ], but, empirically, patients who are re-treated for recurrence of compression fractures a few days after PVP have often new compression fractures of adjacent vertebral bodies directly above or below the PVP-treated vertebral body [ 96 ]. Prophylactic PVP as an optional treatment is preferably performed on normal upper and lower vertebral bodies adjacent PVP-treated vertebra [ 97 , 98 ].…”

Section: Potential Risk Of Pvp Procedures For Osteoporotic Vertebral ...mentioning

confidence: 99%

Current status and challenges of percutaneous vertebroplasty (PVP)

et al. 2022

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A narrative review regarding percutaneous vertebroplasty (PVP) for osteoporotic vertebral fracture (OVF) is provided herein, addressing the epidemic of OVF in Japan, the latest response to the criticism of PVP for OVFs, the indications and potential risks of PVP for OVFs, and a future perspective for PVP. Each year in Japan, approximately 32,000 patients aged 55 years or older suffer from chronic low back pain for several months to several years due to a compression fracture. PVP is one of the surgical treatments for an OVF, and it is less invasive compared to the traditional open surgery. PVP is suitable for OVF patients who have difficulty walking as assessed by the modified Yokoyama’s activities of daily living (ADL) scoring system, and for patients with Kummell's disease diagnosed by CT and MRI examinations. Serious adverse events related to PVP occur in 1.1–3.3% of the cases, but direct deaths from PVP are extremely rare at less than 1%. Recent studies demonstrated that OVF patients treated with PVP are less likely to die after the treatment than non-surgically treated patients, which conflicts with the Cochran reviews’ conclusion not supporting PVP for OVFs. Novel robotic systems and procedure-support devices are being developed, providing a next step toward fully automated PVP procedures.

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“…Nowadays, PVP and percutaneous kyphoplasty (PKP), with safety and efficacy, are widely used in the treatment of patients with OVCF ( 5 – 7 ). However, some studies reported that adverse events such as cement leakage, pulmonary cement embolism, and new vertebral compression fracture (VCF) occurred after PVP or PKP ( 8 – 10 ).…”

Section: Introductionmentioning

confidence: 99%

Risk factors of new vertebral compression fracture after percutaneous vertebroplasty or percutaneous kyphoplasty

Cheng

Cheng²,

Wu³

2022

Front. Endocrinol.

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BackgroundNew vertebral compression fracture (VCF) may occur in patients who underwent percutaneous vertebroplasty (PVP) or percutaneous kyphoplasty (PKP) for osteoporotic vertebral compression fracture (OVCF). However, the risk factors of new VCF remain controversial. The research aimed to analyze the risk factors of new VCF after PVP or PKP.MethodsFrom August 2019 to March 2021, we retrospectively analyzed the patients who underwent PVP or PKP for OVCF at our institution. Age, gender, body mass index (BMI), smoking, drinking, hypertension, diabetes, fracture location, surgical method, Hounsfield unit (HU) value, preoperative degree of anterior vertebral compression (DAVC), bisphosphonates, bone cement volume, bone cement leakage, and cement distribution were collected. The risk factors were obtained by univariate and multivariate analysis of the data.ResultsA total of 247 patients were included in the study. There were 23 patients (9.3%) with new VCF after PVP or PKP. Univariate analysis showed that age (p < 0.001), BMI (p = 0.002), fracture location (p = 0.030), and a low HU value (p < 0.001) were significantly associated with new VCF after PVP or PKP. A low HU value was an independent risk factor for new VCF after PVP or PKP obtained by multivariate regression analysis (OR = 0.963; 95% CI, 0.943–0.984, p = 0.001).ConclusionsIn this study, a low HU value was an independent risk factor of new VCF after PVP or PKP.

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Percutaneous Vertebral Augmentation for Osteoporotic Vertebral Compression Fractures Will Increase the Number of Subsequent Fractures at Adjacent Vertebral Levels: A Systematic Review and Meta-analysis

Cited by 9 publications

References 0 publications

Treatment of Elderly Patients with Acute Symptomatic OVCF: A Study of Comparison of Conservative Treatment and Percutaneous Kyphoplasty

Treatment of Elderly Patients with Acute Symptomatic OVCF: A Study of Comparison of Conservative Treatment and Percutaneous Kyphoplasty

Current status and challenges of percutaneous vertebroplasty (PVP)

Risk factors of new vertebral compression fracture after percutaneous vertebroplasty or percutaneous kyphoplasty

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