Pengaruh pemberian yogurt sinbiotik tepung pisang tanduk terhadap profil lipid tikus sindrom metabolik

Octavia, Zana Fitriana; Djamiatun, Kis; Suci, Nyoman

doi:10.22146/ijcn.19369

Cited by 7 publications

(4 citation statements)

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“…Cosprotanol is a sterol that cannot be absorbed by the intestine, therefore it is released through feces enabling cholesterol to go down. Several studies have shown that lactic acid bacteria can reduce cholesterol in vitro and in vivo (Naim, 2011;Octavia et al, 2017;Wang et al, 2018). Cholesterol reduction is assumed to happen due to its ability to assimilate cholesterol in the small intestine and de-conjugate bile salts.…”

Section: Introductionmentioning

confidence: 99%

The Effect of Probiotic in Milk Fermentation Towards Decreasing Cholesterol Levels: in Vivo Studies

Andriani

Rahayu

Apriliyani

2020

JITEK

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Hypercholesterolemia is a disease that is indicated by the increasing level of cholesterol in the body and also as one of the factors causing cardiovascular disease. An alternative that can be done to prevent hypercholesterolemia is by consuming fermented milk. Skim milk is fermented using probiotic of Lactobacillus acidophillus, Lactobacillus plantarum and Streptococcus thermophilus. The skimmed milk that has been fermented is then tested for total lactic acid bacteria, total acid, pH, and in vivo analysis for antihypercholesterolemia activity using animal model. In this study, the animal models used were male white rats which were grouped into three treatment groups, namely negative control, positive control, and fermented milk group. The result of the study shows that the total lactic acid bacteria, total acid and pH of fermented skim milk were 5.25 x10 9 CFU/mL; 2.190% and pH 4.06, respectively. From the results, fermented milk with probiotics has the ability to reduce cholesterol levels in the blood of male white rats effectively in vivo.

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Section: Introductionmentioning

confidence: 99%

The Effect of Probiotic in Milk Fermentation Towards Decreasing Cholesterol Levels: in Vivo Studies

Andriani

Rahayu

Apriliyani

2020

JITEK

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“…Flavonoids may improve the lipid profile by increasing the activity of the enzyme lipoprotein lipase, which converts Very Low Density Lipoprotein (VLDL) to intermediate density lipoprotein, thereby reducing VLDL accumulation in the liver. The high activity of the lipoprotein lipase enzyme may help to reduce LDL-C levels and increase HDL-C levels (Octavia et al 2017). Saponins can reduce the gastrointestinal lipase enzyme, thereby preventing the absorption of fat in the intestine.…”

Section: Mujayanah Et Almentioning

confidence: 99%

Potential Therapeutic Effects of Tali Bamboo Leaf Tea (Gigantochloa apus) on Lipid Profile of Rats With Metabolic Syndrome

Mujayanah,

Sari,

Listyawati

2023

J Gizi Pangan

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This study aimed to determine the potential of Tali bamboo leaf tea (Gigantochloa apus) on the lipid profile of metabolic syndrome rats. This study is an laboratory-based experimental study using 30 male Wistar rats with metabolic syndrom aged 8 weeks and weighed 150–250 g, that were divided into 5 groups namely negative control (K-), positive control (K+), and three intervention groups with intervention doses of bamboo leaf tea at 300, 600, and 900 mg/200 g BW for 28 days. The results showed that there were significant differences (p<0.05) in High- Density Lipoprotein Cholesterol (HDL-C) and Low-Density Lipoprotein Cholesterol (LDL-C) levels before and after intervention. Tali bamboo leaf tea has the potential to improve the lipid profile of rats with metabolic syndrome (p<0.001).

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“…Penelitian pendukung menjelaskan bahwa prebiotik akan difermentasi mikrofl ora usus menghasilkan Short Chain Fatty Acid (SCFA) (Verbeke et al, 2015) yang berperan dalam metabolisme glukosa dan resistensi insulin pada hiperglikemia (Markowiak dan Katarzyna, 2017). Selain itu, SCFA berperan dalam mengendalikan ekspresi enzim sintesis asam lemak (Ostadrahimi et al, 2015). Oleh karena itu, peneliti tertarik untuk menganalisis pengaruh sinbiotik kefi r pisang batu terhadap kadar glukosa darah dan kadar profil lipid tikus model Sindrom Metabolik yang belum pernah dilakukan sebelumnya.…”

Section: Pendahuluanunclassified

UJI EFEKTIFITAS SINBIOTIK KEFIR TEPUNG PISANG BATU TERHADAP KADAR GLUKOSA DARAH DAN KADAR PROFIL LIPID TIKUS MODEL SINDROM METABOLIK Eﬀectiveness Test of banana (Musa balbisiana) Flour Kefir Synbiotic on Blood Glucose Level and Lipid Profile Level in Metabolic Syndrome Rats Model

Maryusman

Dien

Mail

2021

MGI

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Metabolic Syndrome is a metabolic disorder characterized by hyperglycemia, hypertriglyceridemia, and dyslipidemia which can be repaired through synbiotics. This study is to analyzed the eﬀects of banana (Musa balbisiana) flour kefir synbiotic on blood glucose level and lipid profile level of Metabolic Syndrome rats. This is true experimental study with pre-posttest with control goup design of 24 male Sprague Dawley rats which were divided into 4 groups randomly. Negative control goup (K-) given standard food only, positive control group (K +) given standard food with High Fat Fructose Diet (HFFD), intervention group I (PI) and intervention group II (PII) were given standard food with HFFD and banana (Musa balbisiana) flour kefir synbiotic 1,8 ml/200 g weight/day (PI) and 3,6 ml/200 g weight/day (PII) for three weeks. Blood glucose level was analyzed using glucose oxidase-peroxidase amino antipyrine method, cholesterol level was analyzed using cholesterol oxidase-peroxidase amino antipyrine, and triglyceride level was analyze using glycerol 3 phosphate oxidase phenol amino phenazone method. Result of Analysis of Varian test shows significant diﬀerences in mean between group (p=0,000) followed by PostHoc Bonferroni test or Post Hoc Games-Howel test which showed a mean diﬀerence in the PI and PII groups. Banana (Musa balbisiana) flour kefir synbiotic can reduce blood glucose level and improve lipid profile level.

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Pengaruh pemberian yogurt sinbiotik tepung pisang tanduk terhadap profil lipid tikus sindrom metabolik

Cited by 7 publications

References 0 publications

The Effect of Probiotic in Milk Fermentation Towards Decreasing Cholesterol Levels: in Vivo Studies

The Effect of Probiotic in Milk Fermentation Towards Decreasing Cholesterol Levels: in Vivo Studies

Potential Therapeutic Effects of Tali Bamboo Leaf Tea (Gigantochloa apus) on Lipid Profile of Rats With Metabolic Syndrome

UJI EFEKTIFITAS SINBIOTIK KEFIR TEPUNG PISANG BATU TERHADAP KADAR GLUKOSA DARAH DAN KADAR PROFIL LIPID TIKUS MODEL SINDROM METABOLIK Eﬀectiveness Test of banana (Musa balbisiana) Flour Kefir Synbiotic on Blood Glucose Level and Lipid Profile Level in Metabolic Syndrome Rats Model

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