Peer Reviewed: Plasma Source TOFMS

McClenathan, Denise M.; Ray, Steven J.; Wetzel, William C.; Hieftje, Gary M.

doi:10.1021/ac0415509

Cited by 21 publications

(11 citation statements)

References 27 publications

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“…44 However, DLs for ion-counting ICP-TOFMS are substantially better, down to 0.1 ng L À1 for a 10 s integration. 51 Of course, there is no fundamental reason why ICP-DOFMS could not also be operated in an ion-counting mode if a fast enough optical detector is used. Such ion-counting MCP/phosphor detector arrays have been reported.…”

Section: Detection Limits and Linear Dynamic Rangementioning

confidence: 99%

First inductively coupled plasma-distance-of-flight mass spectrometer: instrument performance with a microchannel plate/phosphor imaging detector

Gundlach‐Graham

Dennis

Ray

et al. 2013

J. Anal. At. Spectrom.

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Here we describe the first combination of a Distance-of-Flight Mass Spectrometry (DOFMS) instrument and an inductively coupled plasma (ICP) ion source. DOFMS is a velocity-based MS technique in which ions of a range of mass-to-charge (m/z) values are detected simultaneously along the length of a spatially selective detector. As a relative of time-of-flight (TOF) MS, DOFMS leverages benefits from both TOFMS and spatially dispersive MS. The simultaneous detection of groups of m/z values improves dynamic range by spreading ion signal across many detector elements and reduces correlated noise by signal ratioing. To ascertain the performance characteristics of the ICP-DOFMS instrument, we have employed a microchannel-plate/ phosphor detection assembly with a scientific CCD to capture images of the phosphor plate. With this simple (and commercially available) detection scheme, elemental detection limits from 2-30 ng L À1 and a linear dynamic range of 5 orders of magnitude (10-10 6 ng L À1 ) have been demonstrated.Additionally, a competitive isotope-ratio precision of 0.1% RSD has been achieved with only a 6 s signal integration period. In addition to first figures of merit, this paper outlines technical considerations for the design of the ICP-DOFMS.

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Section: Detection Limits and Linear Dynamic Rangementioning

confidence: 99%

First inductively coupled plasma-distance-of-flight mass spectrometer: instrument performance with a microchannel plate/phosphor imaging detector

Gundlach‐Graham

Dennis

Ray

et al. 2013

J. Anal. At. Spectrom.

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“…Time-of-flight mass spectrometry has since long been known in instrumental analysis with SIMS, and so on, and been developed into a feasible detection system in ICP-MS [139]. Because of the mass range to be covered (1-238 amu), reasonable acceleration voltages (2 kV), and flight-tube lengths (1 m) permit the generation of 20 000-30 000 mass spectra per s. Both end-on and orthogonal geometry are possible and commercially available (LECO Renaissance and GBC Scientific Optimass 8000).…”

Section: Time-of-flight Icp-msmentioning

confidence: 99%

Inductively Coupled Plasma Spectrometry

Broekaert

2014

Handbook of Spectroscopy

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“…The total analysis time is proportional to the number of m/z values monitored and, for transient signals, an inherent trade-off will always exist between the mass range covered or the number of target nuclides monitored, on one hand, and the achievable precision with which the analyte peak profiles can be defined, on the other. 35 Thus, it is generally accepted that the use of ETV for sample introduction results in a loss in the multi-element capabilities of ICPMS. While this assumption is logical, the key question is to establish how many nuclides can be determined without a significant degration in the analytical performance.…”

Section: Performance In Simultaneous Multi-element Determinationmentioning

confidence: 99%

Extending the capabilities of electrothermal vaporization-inductively coupled plasma mass spectrometry (ETV-ICPMS): Coupling the graphite furnace to a sector field instrument

Resano

Aramendía

Vanhaecke

2009

J. Anal. At. Spectrom.

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This paper reports on the capabilities of the combination of an electrothermal vaporization (ETV) unit and a state-of-art single-collector sector field inductively coupled plasma mass spectrometer (SF-ICPMS). The basic analytical characteristics of this set-up were evaluated and compared to those of the more traditional combination of ETV and quadrupole-based (Q) ICPMS instrumentation. ETV-SF-ICPMS seems capable of providing a superior performance in terms of sensitivity (15-to 20-fold improvement in low resolution mode) and, also in terms of selectivity, as in medium resolution mode significantly lower LODs were achieved, especially for some low-mass elements, for which the most abundant nuclide suffers from spectral overlap as a result of the occurrence of carbon-containing polyatomic ions (e.g., 52 Cr, 28 Si) at low mass resolution. No deterioration was established in terms of stability, linear dynamic range or tolerance to matrix effects in comparison with ETV-Q-ICPMS. Also the possibilities for multi-element monitoring were studied and shown to be similar (monitoring of up to approximately 20 nuclides during the same tube firing is feasible), owing to the enhanced scanning speed and reduced magnet settling time that current SF-ICPMS displays when compared to older SF instrumentation. It is demonstrated that this instrumentation still preserves the most relevant advantages of the ETV technique, such as i) the potential for temporal separation of overlapping isobaric signals (e.g., 102 Ru and 102 Pd; 192 Os and 192 Pt; 130 Te and 130 Ba) under optimum vaporization conditions, and ii) the ability to analyze solid samples directly, as shown by the determination of Cr and Si in biological reference materials. By operating the instrument at higher mass resolution (4000), interference-free conditions could be realized for several isotopes of the target elements and, thus, isotope dilution could be deployed for their quantification, enabling the matrix effects observed to be overcome.

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Peer Reviewed: Plasma Source TOFMS

Cited by 21 publications

References 27 publications

First inductively coupled plasma-distance-of-flight mass spectrometer: instrument performance with a microchannel plate/phosphor imaging detector

First inductively coupled plasma-distance-of-flight mass spectrometer: instrument performance with a microchannel plate/phosphor imaging detector

Inductively Coupled Plasma Spectrometry

Extending the capabilities of electrothermal vaporization-inductively coupled plasma mass spectrometry (ETV-ICPMS): Coupling the graphite furnace to a sector field instrument

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