Pediatric cervicomediastinal hibernoma: A case report

Guidry, Christopher A.; McGahren, Eugene D.; Rodgers, Bryan; Kane, Bartholomew J.

doi:10.1016/j.jpedsurg.2012.10.059

Cited by 7 publications

(5 citation statements)

References 21 publications

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“…Fotografía donde se observa planificación quirúrgica pre-operatoria, presencia de tumoración en toda su extensión, con presencia de cola hacia la región glútea, con atrofia de los músculos de esta región. casos que presentaban áreas pleomórficas que recordaban a un liposarcoma bien diferenciado 21.22. El tratamiento adecuado de este tipo de tumor es la escisión quirúrgica completa, que se realiza sin excesivos problemas ya que la masa está bien delimitada por una cápsula que facilita la separación de los tejidos adyacentes 18,19,22,23,24,25,26 . Dado su comportamiento benigno a nivel local y a que no se ha descrito ningún caso de metástasis la mayoría de los autores no considera necesario un tratamiento adicional, salvo en casos en los que se evidencien áreas sospechosas de liposarcoma, recomendando entonces radioterapia postquirúrgica 18,23,24,25,26 .…”

Section: Discussionunclassified

“…El hibernoma a pesar de ser un tumor infrecuente debe incluirse en el diagnóstico diferencial de los tumores gigantes del tejido celular subcutáneo, tanto a nivel interescapular, como de las otras regiones donde asienta grasa parda 23,24 . El diagnóstico definitivo es a través de estudio histológico de la le-sión y debe incorporarse la Tomografía Computarizada simple y contrastada, así como la resonancia Magnética, para orientar en el diagnóstico de la lesión y su repercusión sobre las estructuras osteomioarticular circundante.…”

Section: Conclusiónunclassified

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Hibernoma dorsal gigante. Presentación de caso

Piloto

Hernández

Poza³

2019

revchilneurocir

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El Hibernoma o lipoma de grasa parda, es un tumor benigno extremadamente infrecuente. Presentamos el caso, de un paciente femenino de 12 años de edad con una tumoración gigante en región dorsal, de origen congénito, con una extensión desde la región cervical baja hasta el sacro, presentaba con ausencia de los músculos de la región glútea, se realizó estudios de imagen, así como química sanguínea, donde se evidencio anemia severa y desnutrición proteico energética, se organizó un equipo multidisciplinario centrado al tratamiento definitivo de la lesión, la cual provocaba además seria deformidad de la columna lumbar (cifoescoliosis), se logró la resección completa de la lesión, con un peso total de 12 Kg, con reconstrucción de los bordes anales sin afectar el esfínter anal, se mantuvo bajo seguimiento durante 1 años sin presentar ninguna recidiva de la lesión.

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Section: Discussionunclassified

Section: Conclusiónunclassified

Hibernoma dorsal gigante. Presentación de caso

Piloto

Hernández

Poza³

2019

revchilneurocir

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“…In suspected cases of a hibernoma with inconclusive radiological findings, a fine-needle aspiration cytology is recommended. A core needle biopsy carries a risk of excessive hemorrhage due to hypervascularity of the tumor and should be avoided, although there are numerous reports considering series of patients with hibernoma that underwent percutaneous biopsy without any complications [11][12][13][14] .…”

Section: Discussionmentioning

confidence: 99%

Large hibernoma of the neck: A case report

Mikić¹,

Folić²,

Boričić

et al. 2019

VOJNOSANIT PREGL

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Introduction. A hibernoma is a rare benign tumor derived from vestigial remnants of brown adipose tissue. In neonates this tissue makes up about 5% of the body mass and its amount greatly decreases after birth, persisting only in scattered subcutaneous areas. In rare cases, brown fat continues to grow leading to a hibernoma that may be located in the head and neck. We present an illustrative case of a large hibernoma of the neck with infraclavicular extension and discuss about diagnostic and treatment difficulties. Case report. A 29-year-old male presented with large, slowly progressive, painless neck mass that was noticed 6 months earlier. Computed tomography (CT) and magnetic resonance (MR) showed a well-vascularized, soft tissue tumor of the lateral region of the neck and supraclavicular fossa with extension below clavicle. Treatment included arterial embolization followed by challenging surgical removal of the tumor. Dissection was performed at III, IV and V levels of the neck, making complete resection possible without the tumor fragmentation or major blood vessels and cranial nerves injuries. The final diagnosis of the hibernoma was made by histopathological analysis. The patient had no signs of recurrence during three-year follow-up. Conclusion. Although the CT scan and MR may raise the suspicion, hibernoma is definitely diagnosed by a pathologist. It is very important to exclude the malignant processes, foremost liposarcoma. The tumor fragmentation during surgery should be avoided because the high vascularity of the tumor tissue carries a substantial risk for hemorrhage. Our experience with preoperative embolization and complete tumor resection in this case showed positive impact on the final outcome.

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“…Hibernomlar, seyrek görülen, fetal kahverengi yağ doku kalıntılarından ortaya çıkan benign yumuşak doku tümörleridir (1). Bu tümörün kahverengi olması vaskülaritesine ve mitokondriden zengin, granüler, eozinofilik sitoplazmalı hücrelerden oluşmasına bağlıdır.…”

Section: Discussionunclassified

A rare soft tıssue tumor ın adults: ''Hıbernoma'' case report

Özbek¹,

Tataroğlu²,

Ozdemir³

et al. 2015

ADUTFD

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Hibernom, fetal kahverengi yağ doku kalıntılarından ortaya çıkan, seyrek görülen, kahverengi yağ doku tümörüdür. Genellikle erişkinlerde görülen, geniş, asidofilik, granüler ve vakuoler sitoplazmalı, santral nükleuslara sahip hücrelerden meydana gelmiş, kapsüllü, sarı-kahverengi, ağrısız ve benign yumuşak doku tümörüdür. Olgumuz 31 yaşında, boynunda şişlik şikayeti olan erkek hastadır. Yapılan görüntülemeler sonucu lezyonun lipom ile uyumlu olduğu bildirilmiştir. Eksizyon sonrası makroskopik olarak kahverengi, yer yer kirli sarı renkli yağ doku görünümünde, kesit yüzleri kahverengi ve hemorajik materyaller izlenmiştir. Mikroskopik incelemede vakuollü, granüler ve eozinofilik sitoplazmalı, yer yer santral yer yer periferik yerleşimli küçük, yuvarlak nükleuslu hücrelerden oluşan tümör gözlenmiştir. Uygulanan histokimyasal Oil-Red-O ile bu hücreler boyanmış ve lipositlerle uyumlu olarak değerlendirilmiştir. Bu bulgularla hastaya hibernom tanısı konulmuştur. Histopatolojik olarak, hibernom, granüler hücreli miyoblastom, yuvarlak hücreli liposarkom, lipoblastomatozis, sebase adenom, pleomorfik lipom ve kahverengi yağın normal birikimlerinden ayırt edilmelidir. Tedavide tümörün total eksizyonu yeterlidir. Bu olgu, nadir görülmesi, basit eksizyonla tedavi edilebilmesi ve özellikle yüksek damarlanma gösteren lezyonların ayırıcı tanısında akılda tutulması gerektiği için sunulmaya değer bulunmuştur.

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Pediatric cervicomediastinal hibernoma: A case report

Cited by 7 publications

References 21 publications

Hibernoma dorsal gigante. Presentación de caso

Hibernoma dorsal gigante. Presentación de caso

Large hibernoma of the neck: A case report

A rare soft tıssue tumor ın adults: ''Hıbernoma'' case report

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