Patterns of Postoperative Radiotherapy for Head and Neck Cancer in Italy: A Prospective, Observational Study by the Head and Neck Group of the Italian Association for Radiation Oncology (AIRO)

Abstract

Three issues emerged from our study as potential targets for future investigations: the impact on clinical outcome of the interval between surgery and the start of PORT; factors driving radiation oncologists to overtreat volumes at low risk of recurrence; and problems associated with the delivery of concomitant chemotherapy.

Radiotherapy for Head and Neck Cancer in Lombardy: A Survey by the Lombardy Group of the Italian Association for Radiation Oncology

“…The disperse data on use of concomitant CHT in the postoperative setting was an expected finding, reflecting the results of another Italian observational study on postoperative RT in head and neck cancer, where it emerged that "several aspects of treatment were quite heterogeneous…and concomitant CHT still appears to be delivered suboptimally, with potential situations of both under-and overtreatment" (17).…”

Adding Concomitant Chemotherapy to Postoperative Radiotherapy in Oral Cavity Carcinoma with Minor Risk Factors: Systematic Review of the Literature and Meta-Analysis

“…Only studies including oncological outcomes (overall survival, disease-free survival, and local recurrence-free survival) for patients affected by oral cavity carcinoma (OCC) treated with post-operative chemoradiotherapy who showed the presence of minor risk factors were analyzed. Criteria for exclusion are reported in the Supplementary Materials Table S2 [ 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 ,…”