Pattern of neoplastic and non-neoplastic lesions of ovary: a five-year study in a tertiary care centre of rural india

Abstract

Background: Most common ovarian lesions include benign non-neoplastic lesions including functional cysts and neoplastic lesions. While among cancers of female genital tract, the incidence of ovarian cancer ranks below only carcinoma of cervix and endometrium. The aim of this study was to observe and evaluate the frequency and morphological pattern of different ovarian pathologies encountered in this tertiary care centre of rural India.Methods: This was a retrospective five years observational study (2012-16) and conducted at Department of Pathology of UPUMS, Saifai. The study material included 264 histopathology specimens received in our department.Results: Total 264 cases of ovarian pathologies were studied, in which 147 cases were non-neoplastic while remaining 117 cases were neoplastic. The most common non-neoplastic lesion was follicular cyst (51.7%), followed by corpus luteal cyst (30.61%), endometriosis (15.64%). Among 117 neoplastic cases, 87 cases (74.35%) were benign, 5 cases (4.27%) were borderline tumours and 25 cases (21.36%) were diagnosed malignant. Serous cystadenoma was most common benign tumour with 53 cases (45.29%) followed by 20 cases (17.09%) of dermoid cyst and 12 cases (10.25%) of mucinous cystadenoma. While in malignant tumours, serous adenocarcinoma were most common (4.27%) followed by mucinous adenocarcinoma (2.56%).Conclusions: In our study, non-neoplastic ovarian lesions were more commonly seen than neoplastic lesions. Surface epithelial tumours were most common histologic type in all age groups. While serous adenocarcinoma was most common ovarian malignancy seen. Both non-neoplastic as well as neoplastic lesions of ovary often present with similar clinical and radiological features. So histopathological study is essential to diagnose ovarian tumours.

Histomorphological pattern of neoplastic and non-neoplastic lesions of ovary in Ajmer region of Rajasthan, India

“…In the present study out of total 160 non-neoplastic cases, follicular cyst was most common lesion 71 cases (44.38%) followed by 33 cases (20.625%) of corpus luteal cyst. Nearly similar results were reported by Maurya G. et al [9] and Gupta AK et al [10] . Out of 120 neoplastic lesions in our study there were 80 benign (66.67%), 8 borderline (6.66%) and 32 malignant lesions (26.67%), while M Thirukumar et al [11] .…”

“…Non-neoplastic lesions were more than neoplastic lesions. Similar larger proportion of nonneoplastic lesions 147 cases (55.68%) out of 264 ovarian lesions were reported by Maurya G. et al [9] . In the present study out of total 160 non-neoplastic cases, follicular cyst was most common lesion 71 cases (44.38%) followed by 33 cases (20.625%) of corpus luteal cyst.…”

Age specific clinicopathological profile of ovarian mass

“…This study showed most common age group for occurrence of ovarian tumor was in 20-29 years (36%), followed 30-39 years (23.6%), similar with the findings of other studies. 6,11,12,18,19 Ovarian tumor may occur at any age, including infancy and childhood. 18 The peak incidence is between 21 to 40 years and about 80% are benign.…”

Incidence of neoplastic lesions of female genital tract in a tertiary care centre: A 3 year retrospective study

“…In ovaries, the most common ovarian lesions include benign non neoplastic lesions and neoplastic lesions including functional cysts and ovarian tumors respectively. Ovarian lesions affect all age groups [5] . The clinical course of different histologic types of ovarian ~ 7 ~ tumors are much variable [6,7] .…”