Pathophysiological status and nutritional therapy of peptic ulcer: An update

Kulshreshtha, Mayank; Srivastava, Gunja; Singh, Mridweeka

doi:10.4103/ed.ed_11_17

Cited by 13 publications

(4 citation statements)

References 1 publication

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“…Peptic ulcers are one of the major human illnesses of the entire gastrointestinal tract, which affecting nearly 10% of the world’s population, among them, 5% suffer from gastric ulcers ( 106 ). The imbalance between endogenous aggressive factors and cytoprotective factors lead to the pathogenesis of gastric ulcers, which occur mainly in the stomach and the proximal duodenum ( 107 ). Recently, scientific evaluations on different types of phytosterols have been identified and revealed to exhibit potential prevention or cure activities of peptic ulcers.…”

Section: Biological Activities and Health Benefits Of Phytosterols In...mentioning

confidence: 99%

Phytosterols in rice bran and their health benefits

Liu,

et al. 2023

Front. Nutr.

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With the continuous technological innovation in the high-value utilization of rice bran byproducts, rice bran oil retains a higher concentration of beneficial components such as a well-balanced composition of fatty acids and abundant phytosterols. This makes it a highly nutritious and healthy vegetable oil. This review provides an overview of the advancements made in separating, purifying, and processing phytosterols in rice bran oil. The review also introduces techniques for assessing the stability of rice bran oil. Moreover, the review emphasizes the nutritional value of phytosterols found in rice bran oil, highlighting their various health benefits, including their anticancer, anti-inflammatory, anti-allergic, antibacterial, cholesterol-lowering, skin-protective, anti-obesity, anti-diabetic, neuroprotective, gastroprotective, and immune-enhancing effects. Attaining a comprehensive understanding of the research progress made in phytosterols derived from rice bran oil can offer valuable guidance for the efficient utilization of rice bran.

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Section: Biological Activities and Health Benefits Of Phytosterols In...mentioning

confidence: 99%

Phytosterols in rice bran and their health benefits

Liu,

et al. 2023

Front. Nutr.

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“…As confirmed by an endoscopic study[ 115 ], patients with peptic ulcers who avoided a milk-based diet had better ulcer cicatrization results than those who consumed milk. However, patients with a peptic ulcer can consume a moderate amount of dairy products according to their tolerance to benefit from their high nutritional content[ 116 ].…”

Section: Cow’s Milk-related Functional Gastrointestinal Disordersmentioning

confidence: 99%

Cow’s milk-induced gastrointestinal disorders: From infancy to adulthood

Al‐Biltagi¹,

Saeed²,

Bediwy³

et al. 2022

World J Clin Pediatr

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Milk is related to many gastrointestinal disorders from the cradle to the grave due to the many milk ingredients that can trigger gastrointestinal discomfort and disorders. Cow’s milk protein allergy (CMPA) is the most common food allergy, especially in infancy and childhood, which may persist into adulthood. There are three main types of CMPA; immunoglobulin E (IgE)-mediated CMPA, non-IgE-mediated CMPA, and mixed type. CMPA appears before the first birthday in almost all cases. Symptoms may start even during the neonatal period and can be severe enough to simulate neonatal sepsis. CMPA (often non-IgE mediated) can present with symptoms of gastroesophageal reflux, eosinophilic esophagitis, hemorrhagic gastritis, food protein-induced protein-losing enteropathy, and food protein-induced enterocolitis syndrome. Most CMPAs are benign and outgrown during childhood. CMPA is not as common in adults as in children, but when present, it is usually severe with a protracted course. Lactose intolerance is a prevalent condition characterized by the development of many symptoms related to the consumption of foods containing lactose. Lactose intolerance has four typical types: Developmental, congenital, primary, and secondary. Lactose intolerance and CMPA may be the underlying pathophysiologic mechanisms for many functional gastrointestinal disorders in children and adults. They are also common in inflammatory bowel diseases. Milk consumption may have preventive or promoter effects on cancer development. Milk may also become a source of microbial infection in humans, causing a wide array of diseases, and may help increase the prevalence of antimicrobial resistance. This editorial summarizes the common milk-related disorders and their symptoms from childhood to adulthood.

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“…Surgical intervention may be necessary in extreme cases if complications such as bleeding or perforation occur. Peptic ulcers can recover and recurrence can be avoided with the right care and lifestyle changes [11]. On the other hand, to avoid complications and guarantee efficient treatment of the illness, early detection and fast medical attention are essential.…”

Section: Introduction 11 Peptic Ulcermentioning

confidence: 99%

Alleviating Ulcer Burdens Examining the Potential of Albizia Odoratissima Bark Extract as a Therapeutic Agent in Mice

Sultana,

Basha,

Teja

et al. 2024

UPJOZ

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Ulcerative stomach disease continues to be a prevalent gastrointestinal illness associated with high worldwide morbidity and medical costs. While nonsteroidal anti-inflammatory drugs (NSAIDs) and Helicobacter pylori infection are well-known risk factors for the development of peptic ulcers, recent evidence suggests a complex interaction between host factors and the gut microbiota in ulcer etiology. This study provides a comprehensive review of recent research investigating the relationship between the genesis and progression of peptic ulcers and dysbiosis of the gut microbiota. The study highlights several natural compounds, such as flavonoids, polyphenols, alkaloids, and polysaccharides, that have demonstrated anti-ulcer activity in experimental models and clinical trials. Mechanistic understanding clarifies the many pathways, including antibacterial, anti-inflammatory, and antioxidant ones, through which these drugs perform their medicinal effects. It is interesting to note that many natural compounds focus on many pathogenic procedures that aid in the development and spread of ulcers, resulting in multifactorial effects. Albizia odoratissima is a member of the Fabaceae family and has been used traditionally in many folk medicines due to its medicinal characteristics. This study used experimental models of stomach ulceration to investigate potential anti-ulcer properties of methanolic bark extract from Albizia odoratissima (MAO). The anti-ulcer qualities of MAO were evaluated in rats using models of stomach ulceration brought on by HCL. Many parameters were assessed when different doses of MAO were administered orally, including the ulcer index, mucosal injury to the stomach, mucin content, and antioxidant enzyme levels. Additionally, a histological analysis was carried out to evaluate the possible protective qualities of MAO against harm to the stomach mucosa.

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Pathophysiological status and nutritional therapy of peptic ulcer: An update

Cited by 13 publications

References 1 publication

Phytosterols in rice bran and their health benefits

Phytosterols in rice bran and their health benefits

Cow’s milk-induced gastrointestinal disorders: From infancy to adulthood

Alleviating Ulcer Burdens Examining the Potential of Albizia Odoratissima Bark Extract as a Therapeutic Agent in Mice

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