Pathologic change in soft tissues associated with radiographically ‘normal’ third molar impactions

Glosser, J.W.; Campbell, John H.

doi:10.1054/bjom.1999.0061

Cited by 99 publications

(105 citation statements)

References 6 publications

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“…The results of this study showed that 52% of samples exhibited squamous metaplasia indistinguishable from the histological changes found in dentigerous cyst and 26% samples exhibited chronic nonspecific inflammatory tissue. This finding is consistent with previous reports (Rakprasitkul, 2001;Baykul et al, 2005), however shows a higher incidence that has been reported in other studies related with impacted third molars (Glosser and Campbell, 1999;Adelsperger et al, 2000). We found a correlation between the incidence of cystic change in follicular tissues and age.…”

Section: Discussionsupporting

confidence: 94%

Ki-67 expression in pericoronal tissues of impacted mandibular third molars

Sümer¹,

Yıldız²,

Sümer

et al. 2012

jecm

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Section: Discussionsupporting

confidence: 94%

Ki-67 expression in pericoronal tissues of impacted mandibular third molars

Sümer¹,

Yıldız²,

Sümer

et al. 2012

jecm

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“…Although several authors have reported that the risk of the development of cysts and tumors around third molars is extremely low (Güven et al, 2000;Kostopoulou et al, 2000;Stephens et al, 1989), others observed a high incidence of pathological changes in the DF, especially associated with the dentigerous cyst (DC) (Baykul et al, 2005;Daley & Wysocki, 1995;Glosser & Campbell, 1999). However, the discrepancy in the incidence rates of pathological changes in the DF is due to lack of standardization in the methods of these studies that used different parameters for radiographic and histological analysis of the cases.…”

Section: Discussionmentioning

confidence: 99%

Immunohistochemical Analysis of Human Homologue of Drosophila Patched (PTCH) in Dental Follicles of Impacted Third Molars

et al. 2012

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SUMMARY:This study investigated the immunodetection of PTCH in epithelial components of dental follicles associated with impacted third molars without radiographic signs of pathosis. One hundred and five specimens of dental follicles associated with impacted third molars with incomplete rhizogenesis (between Nolla's stage 6 and 9) were surgically removed from 56 patients. Epithelial cell proliferation was determined by using immunohistochemical labeling. Statistical analysis was performed using Fisher exact test and a level of significance of 5%. Of the 105 dental follicles collected, 3 were PTCH-positive. The specimens with squamous metaplasia and epithelial hyperplasia had higher rates of positivity for PTCH, as well as those with active remnants of odontogenic epithelium. This study suggests that the odontogenic cells of the dental follicle might be proliferating during the rhizogenesis, while the squamous metaplasia and hyperplasia of the epithelial lining and proliferative odontogenic epithelial rests show the differentiation potential of dental follicles.

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“…12 A pesar de esto, algunos autores afirman que la incidencia de quistes dentígeros asociados con terceros molares incluídos es mayor que lo estimado a partir de los estudios radiológicos aisladamente. 11,13 …”

Section: Discussionunclassified

“…12 In spite of all this, some authors claim that the incidence of dentigerous cysts associated with impacted third molars is greater than has been assumed from radiological studies alone. 11,13 It would be desirable for detailed studies to be carried out with the aim of establishing reference values regarding the size of radiolucent pericoronal images of impacted third molars, and the relationship with an increase in the probability of the cysts being, or becoming, a histologically diagnosed dentigerous cyst. This would allow an aggressive therapeutic approach to be adopted in cases with a high probability of cystic formation, and the resulting deleterious effects could be avoided or diminished.…”

Section: Conclusionesmentioning

confidence: 99%

Actitud terapéutica ante sacos foliculares de terceros molares incluídos

González-García

Hernández

Moreno

et al. 2005

Rev Esp Cirug Oral y Maxilofac

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Resumen: El quiste dentígero o folicular es un quiste odontogénico del desarrollo. Está revestido por el epitelio del folículo dentario, y suele estar en relación con un diente permanente incluído. Presentamos el caso clíni-co de un paciente en el que se observa la aparición de un quiste dentíge-ro a partir del saco folicular de un tercer molar incluído no exodonciado, y lo comparamos con la evolución de un cordal incluído y su saco folicular contralaterales en los que se realizó la exodoncia. El tratamiento definitivo del quiste dentígero asociado a un tercer molar incluído es quirúr-gico, con la exodoncia de la pieza y enucleación del quiste. Los sacos foliculares mayores de 2 mm asociados a terceros molares incluídos evolucionan en numerosas ocasiones a quistes foliculares. Está indicada la exodoncia de dichos cordales para evitar la evolución a quiste dentígero.Palabras clave: Quiste dentígero; Folículo dental; Tercer molar; Diente incluído. RecibidoRev Esp Cir Oral y Maxilofac 2005;27,2 (marzo-abril):80-84 © 2005 ergon Rev Esp Cir Oral y Maxilofac 2005;27,2 (marzo-abril):80-84 © 2005 ergon 81 R. González García y cols. IntroducciónEl quiste dentígero o folicular es un quiste odontogénico del desarrollo. Es el segundo en frecuencia tras el quiste radicular, y está revestido por el epitelio del folículo dentario. 1 Frecuentemente se presenta en relación con un diente permanente incluído, con más frecuencia el tercer molar inferior. 2 Lo habitual es que sea central o coronario y asintomático.Las indicaciones para la exodoncia de terceros molares incluídos son en muchos casos controvertidas. 3 No hay un acuerdo general sobre la exodoncia del cordal asintomático. Es necesario considerar las posibles complicaciones de una exodoncia al plantear la indicación de cirugía.La presencia de una lesión quística asociada a tercer molar inferior es indicativa de exodoncia y quistectomía. Sin embargo, cuando la formación quística no es evidente, y en su lugar aparece una imagen radiolúcida compatible con el saco folicular de la pieza incluí-da, la indicación de exodoncia profiláctica se hace más problemá-tica, sobre todo si se considera la nada inususal evolución espontánea de un saco folicular a quiste dentígero. Caso clínicoPaciente varón de 28 años que acude a nuestro Servicio presentando dolor hemimandíbular izquierdo y fiebre. No presenta antecedentes patológicos de interés. La exploración física no refleja ningún signo específico, pero sí dolor a la palpación de los tejidos pericoronarios del tercer molar inferior izquierdo. Se realiza analítica de Urgencias observando un leve aumento del número de leucocitos, sin otra alteración destacable. En la ortopantomografía (OPG) se visualizan ambos terceros molares incluídos, en posición mesioangular, con sendos sacos foliculares, el derecho de mayor tamaño (Fig. 1). Con la sospecha de posible infección de causa odontógena (pericoronaritis) se instaura tratamiento antibiótico, con resolución completa del cuadro. Se recomienda exodoncia de ambos cordales inferiores. El estudi...

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Pathologic change in soft tissues associated with radiographically ‘normal’ third molar impactions

Cited by 99 publications

References 6 publications

Ki-67 expression in pericoronal tissues of impacted mandibular third molars

Ki-67 expression in pericoronal tissues of impacted mandibular third molars

Immunohistochemical Analysis of Human Homologue of Drosophila Patched (PTCH) in Dental Follicles of Impacted Third Molars

Actitud terapéutica ante sacos foliculares de terceros molares incluídos

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